His scientific interests lie mostly in Cell biology, Internal medicine, Endocrinology, Chondrocyte and Cartilage. His Internal medicine research incorporates elements of Ossification, Chondrogenesis, Bone morphogenetic protein and Osteoblast. The study incorporates disciplines such as Genetically modified mouse and Core binding factor in addition to Chondrogenesis.
Motomi Enomoto-Iwamoto has researched Endocrinology in several fields, including Complementary DNA, Receptor, Growth factor and Peptide. His Chondrocyte research incorporates themes from Type I collagen, Extracellular matrix, Endochondral ossification and Alkaline phosphatase. His Cartilage study integrates concerns from other disciplines, such as Intramembranous ossification and Pathology.
Cell biology, Chondrocyte, Internal medicine, Endocrinology and Cartilage are his primary areas of study. The Cell biology study which covers Endochondral ossification that intersects with Intramembranous ossification. His Chondrocyte research integrates issues from Type I collagen, Extracellular matrix, RUNX2 and Cellular differentiation.
Motomi Enomoto-Iwamoto has included themes like Hereditary multiple exostoses, Ossification and Indian hedgehog in his Internal medicine study. His Endocrinology research is multidisciplinary, incorporating perspectives in Phenotype, Osteoblast, Receptor, Bone morphogenetic protein and Retinoic acid. His Cartilage research includes themes of Catenin and Pathology.
Motomi Enomoto-Iwamoto spends much of his time researching Cell biology, Cartilage, Extracellular matrix, Aggrecan and Chondrocyte. Progenitor cell, Chondrogenesis and Wnt signaling pathway are among the areas of Cell biology where Motomi Enomoto-Iwamoto concentrates his study. His work deals with themes such as Matrix, Mesenchymal stem cell and Stem cell, which intersect with Cartilage.
The Extracellular matrix study combines topics in areas such as Agonist, Retinoic acid receptor gamma and Gene expression. His Chondrocyte study combines topics in areas such as Mechanotransduction, Internal medicine and Endocrinology. His primary area of study in Internal medicine is in the field of Type I collagen.
Motomi Enomoto-Iwamoto mostly deals with Cell biology, Meniscus, Aggrecan, Fibril and Cartilage. His work on Cell biology deals in particular with Chondrogenesis and Wnt signaling pathway. The various areas that Motomi Enomoto-Iwamoto examines in his Meniscus study include Immunohistochemistry, Pathology, Sclerostin and Reduction.
His Ossification center study in the realm of Cartilage interacts with subjects such as Vascular endothelial growth factor. His work on Mechanotransduction is being expanded to include thematically relevant topics such as Chondrocyte. His Chondrocyte research is multidisciplinary, relying on both Endocrinology, Dwarfism, Osteogenesis imperfecta, Osteoblast and Unfolded protein response.
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Cbfa1 is a positive regulatory factor in chondrocyte maturation.
Hirayuki Enomoto;Motomi Enomoto-Iwamoto;Masahiro Iwamoto;Shintaro Nomura.
Journal of Biological Chemistry (2000)
Skeletal Malformations Caused by Overexpression of Cbfa1 or Its Dominant Negative Form in Chondrocytes
Chisato Ueta;Masahiro Iwamoto;Naoko Kanatani;Carolina Yoshida.
Journal of Cell Biology (2001)
Developmental Regulation of Wnt/β-Catenin Signals Is Required for Growth Plate Assembly, Cartilage Integrity, and Endochondral Ossification
Yoshihiro Tamamura;Tomohiro Otani;Naoko Kanatani;Eiki Koyama.
Journal of Biological Chemistry (2005)
A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis.
Eiki Koyama;Yoshihiro Shibukawa;Motohiko Nagayama;Hiroki Sugito.
Developmental Biology (2008)
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists
Kengo Shimono;Wei En Tung;Wei En Tung;Christine MacOlino;Amber Hsu Tsai Chi.
Nature Medicine (2011)
BMP SIGNALING DURING BONE PATTERN DETERMINATION IN THE DEVELOPING LIMB
Y. Kawakami;T. Ishikawa;M. Shimabara;N. Tanda.
Development (1996)
The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis.
Motomi Enomoto-Iwamoto;Jirouta Kitagaki;Eiki Koyama;Yoshihiro Tamamura.
Developmental Biology (2002)
Wnt/ β -catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration
Takahito Yuasa;Tomohiro Otani;Tatsuya Koike;Masahiro Iwamoto.
Laboratory Investigation (2008)
Bone Morphogenetic Protein Signaling Is Required for Maintenance of Differentiated Phenotype, Control of Proliferation, and Hypertrophy in Chondrocytes
Motomi Enomoto-Iwamoto;Masahiro Iwamoto;Yoshiki Mukudai;Yasuhiko Kawakami.
Journal of Cell Biology (1998)
Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb.
Kimitoshi Yagami;Jo-Young Suh;Motomi Enomoto-Iwamoto;Eiki Koyama.
Journal of Cell Biology (1999)
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