Michael J. Zuscik

Overview

Best Publications

• Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

  Mei Zhu;Dezhi Tang;Dezhi Tang;Qiuqian Wu;Suyang Hao

  569
  Citations

• Inhibition of β-Catenin Signaling in Articular Chondrocytes Results in Articular Cartilage Destruction

  Mei Zhu;Mo Chen;Michael Zuscik;Qiuqian Wu

  314
  Citations

• Regulation of chondrogenesis and chondrocyte differentiation by stress

  Michael J. Zuscik;Matthew J Hilton;Xinping Zhang;Di Chen

  304
  Citations

• Targeting the gut microbiome to treat the osteoarthritis of obesity

  Eric M. Schott;Christopher W. Farnsworth;Alex Grier;Jacquelyn A. Lillis

  218
  Citations

• RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development

  Yufeng Dong;Alana M. Jesse;Anat Kohn;Lea M. Gunnell

  198
  Citations

• Reduced COX-2 expression in aged mice is associated with impaired fracture healing.

  Amish A Naik;Chao Xie;Michael J. Zuscik;Paul Kingsley

  194
  Citations

• Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis

  Erik R. Sampson;Matthew J. Hilton;Ye Tian;Di Chen

  192
  Citations

• Smad3‐Deficient Chondrocytes Have Enhanced BMP Signaling and Accelerated Differentiation

  Tian Fang Li;Michael Darowish;Michael J. Zuscik;Di Chen

  173
  Citations

• High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury

  Robert A Mooney;Erik R Sampson;Jaclyn Lerea;Randy N Rosier

  171
  Citations

• Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency.

  Jonathan J. Carmouche;J. Edward Puzas;Xinping Zhang;Prarop Tiyapatanaputi

  169
  Citations

• Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-β delays hypertrophy and PGE2 inhibits terminal differentiation

  Xinping Zhang;Navid Ziran;J.Jeffery Goater;Edward M Schwarz

  163
  Citations

• Overexpression of the α 1B -adrenergic receptor causes apoptotic neurodegeneration: Multiple system atrophy

  Michael J. Zuscik;Scott Sands;Sean A. Ross;David J J Waugh

  146
  Citations

• Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis.

  Hicham Drissi;Michael Zuscik;Randy Rosier;Regis O’Keefe

  144
  Citations

• ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.

  Donghui Zhang;Edward M Schwarz;Randy N Rosier;Michael J Zuscik

  142
  Citations

• Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.

  Qiuqian Wu;Kyung-Ok Kim;Erik R. Sampson;Di Chen

  142
  Citations

• Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2

  Michihiko Usui;Lianping Xing;Hicham Drissi;Michael Zuscik

  136
  Citations

• Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway

  Tian-Fang Li;Yufeng Dong;Andreia M Ionescu;Randy N Rosier

  127
  Citations

• High-Fat Diet Causes Bone Loss in Young Mice by Promoting Osteoclastogenesis Through Alteration of the Bone Marrow Environment

  Lei Shu;Eric Beier;Tzong Sheu;Hengwei Zhang

  123
  Citations

• Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.

  Matthew L. Brown;Kiminori Yukata;Christopher W. Farnsworth;Ding Geng Chen

  122
  Citations

• Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue.

  Meina Wang;Dezhi Tang;Dezhi Tang;Bing Shu;Bing Shu;Baoli Wang;Baoli Wang

  121
  Citations