D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 9,727 121 World Ranking 6545 National Ranking 3034

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His main research concerns Cell biology, Internal medicine, Endocrinology, Phosphodiesterase and Angiotensin II. His Kinase and Signal transduction study in the realm of Cell biology interacts with subjects such as Vascular smooth muscle. Chen Yan works mostly in the field of Kinase, limiting it down to concerns involving Endothelial stem cell and, occasionally, Protein kinase B.

Within one scientific family, he focuses on topics pertaining to Cyclic nucleotide under Internal medicine, and may sometimes address concerns connected to Calmodulin and Hippocampus. His work in Phosphodiesterase addresses subjects such as Olfactory epithelium, which are connected to disciplines such as Messenger RNA, Enzyme, Electrophysiology and Molecular cloning. The study incorporates disciplines such as Myocyte and Cyclophilin A in addition to Angiotensin II.

His most cited work include:

  • Cyclic GMP Phosphodiesterases and Regulation of Smooth Muscle Function (438 citations)
  • Cyclophilin A Is a Secreted Growth Factor Induced by Oxidative Stress (321 citations)
  • Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. (266 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Internal medicine, Endocrinology, Signal transduction and Angiotensin II. Chen Yan undertakes interdisciplinary study in the fields of Cell biology and Vascular smooth muscle through his works. His Internal medicine research incorporates themes from Apoptosis and Downregulation and upregulation.

The concepts of his Endocrinology study are interwoven with issues in Phosphodiesterase, Phosphodiesterase 3 and Heart failure. His studies deal with areas such as Protein kinase A, Pharmacology and Cyclic nucleotide as well as Phosphodiesterase. His Signal transduction research is multidisciplinary, incorporating elements of Proinflammatory cytokine and Cancer research.

He most often published in these fields:

  • Cell biology (44.79%)
  • Internal medicine (36.46%)
  • Endocrinology (35.42%)

What were the highlights of his more recent work (between 2017-2021)?

  • Pharmacology (8.33%)
  • Heart failure (9.90%)
  • Pathological (3.12%)

In recent papers he was focusing on the following fields of study:

Chen Yan mainly investigates Pharmacology, Heart failure, Pathological, Cell biology and Vinpocetine. His Pharmacology research is multidisciplinary, incorporating perspectives in Tumor necrosis factor alpha, Proinflammatory cytokine, Aorta and Degenerative disease. His Heart failure research integrates issues from PDE1, Cyclic nucleotide phosphodiesterases, Contractility and Nucleotide.

He focuses mostly in the field of Pathological, narrowing it down to topics relating to Cyclic nucleotide phosphodiesterase and, in certain cases, Bioinformatics, Second messenger system, Intracellular, Cause of death and Cardiac hypertrophy. His study in the field of CAMP signaling is also linked to topics like Adenosine A2 Receptor. His studies in Vinpocetine integrate themes in fields like Pathogenesis, Inflammation, Middle ear, Otitis and MAPK/ERK pathway.

Between 2017 and 2021, his most popular works were:

  • Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients. (32 citations)
  • An update on vinpocetine: New discoveries and clinical implications. (28 citations)
  • Multiprotein Complex With TRPC (Transient Receptor Potential-Canonical) Channel, PDE1C (Phosphodiesterase 1C), and A2R (Adenosine A2 Receptor) Plays a Critical Role in Regulating Cardiomyocyte cAMP and Survival. (26 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His main research concerns Speech recognition, Spoofing attack, Neuroscience, Heart failure and Pharmacology. His study in the field of Voice command device also crosses realms of S Voice, Interaction method and Microphone. He has included themes like Key, Reliability and Biometrics in his Spoofing attack study.

His research integrates issues of Stroke and Dementia, Disease in his study of Neuroscience. He interconnects Nucleotide, Cyclic nucleotide phosphodiesterases, Cause of death and Cyclic nucleotide phosphodiesterase in the investigation of issues within Heart failure. His Pharmacology study combines topics from a wide range of disciplines, such as Pathological, Pathogenesis, Inflammation, IκBα and Cerebral circulation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cyclic GMP Phosphodiesterases and Regulation of Smooth Muscle Function

Sergei D. Rybalkin;Chen Yan;Karin E. Bornfeldt;Joseph A. Beavo.
Circulation Research (2003)

679 Citations

Cyclophilin A Is a Secreted Growth Factor Induced by Oxidative Stress

Zheng-Gen Jin;Matthew G. Melaragno;Duan-Fang Liao;Chen Yan.
Circulation Research (2000)

451 Citations

Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms.

Kimio Satoh;Patrizia Nigro;Tetsuya Matoba;Michael R. O'Dell.
Nature Medicine (2009)

406 Citations

DolphinAttack: Inaudible Voice Commands

Guoming Zhang;Chen Yan;Xiaoyu Ji;Tianchen Zhang.
computer and communications security (2017)

391 Citations

Fluid shear stress inhibits TNF-α activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members

James Surapisitchat;Ryan J. Hoefen;Xinchun Pi;Masanori Yoshizumi.
Proceedings of the National Academy of Sciences of the United States of America (2001)

297 Citations

Endothelial Atheroprotective and Anti-inflammatory Mechanisms

Bradford C. Berk;Jun Ichi Abe;Wang Min;James Surapisitchat.
Annals of the New York Academy of Sciences (2008)

291 Citations

Upregulation of Phosphodiesterase 1A1 Expression Is Associated With the Development of Nitrate Tolerance

Dongsoo Kim;Sergei D. Rybalkin;Xinchun Pi;Yining Wang.
Circulation (2001)

253 Citations

Differential Regulation of Mitogen-Activated Protein Kinases ERK1/2 and ERK5 by Neurotrophins, Neuronal Activity, and cAMP in Neurons

Jane E. Cavanaugh;James Ham;Michal Hetman;Steve Poser.
The Journal of Neuroscience (2001)

249 Citations

Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons

Chen Yan;A. Z. Zhao;J. K. Bentley;K. Loughney.
Proceedings of the National Academy of Sciences of the United States of America (1995)

247 Citations

Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium

Chen Yan;Masafumi Takahashi;Masanori Okuda;Jiing-Dwan Lee.
Journal of Biological Chemistry (1999)

246 Citations

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Best Scientists Citing Chen Yan

Bradford C. Berk

Bradford C. Berk

University of Rochester

Publications: 75

Jun Ichi Abe

Jun Ichi Abe

The University of Texas MD Anderson Cancer Center

Publications: 38

Hiroaki Shimokawa

Hiroaki Shimokawa

Tohoku University

Publications: 36

Joseph A. Beavo

Joseph A. Beavo

University of Washington

Publications: 35

Jian-Dong Li

Jian-Dong Li

Georgia State University

Publications: 28

David A. Kass

David A. Kass

Johns Hopkins University School of Medicine

Publications: 26

Viacheslav O. Nikolaev

Viacheslav O. Nikolaev

Universität Hamburg

Publications: 25

Vincent C. Manganiello

Vincent C. Manganiello

National Institutes of Health

Publications: 21

Daniel R. Storm

Daniel R. Storm

University of Washington

Publications: 21

Hanjoong Jo

Hanjoong Jo

Georgia Institute of Technology

Publications: 17

Emilio Hirsch

Emilio Hirsch

University of Turin

Publications: 17

Michael Bukrinsky

Michael Bukrinsky

George Washington University

Publications: 16

Richard T. Premont

Richard T. Premont

University Hospitals of Cleveland

Publications: 15

Jong-Sup Bae

Jong-Sup Bae

Kyungpook National University

Publications: 15

Sharron H. Francis

Sharron H. Francis

Vanderbilt University

Publications: 15

Qingbo Xu

Qingbo Xu

Queen Mary University of London

Publications: 14

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