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Biology and Biochemistry

D-Index
70
Citations
14457
World Ranking
7152
National Ranking
3281

Overview

Jun Ichi Abe is a researcher affiliated with The University of Texas MD Anderson Cancer Center in the United States, with a focus on fields spanning medicine, immunology, and molecular biology. Their scholarly output integrates various subfields including immunology, molecular biology, surgery, oncology, and cell biology.

The primary themes of Jun Ichi Abe's research include several aspects of immune function and pathology:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Kawasaki Disease and Coronary Complications
  • Immune Cells in Cancer
  • IL-33, ST2, and ILC Pathways
  • Streptococcal Infections and Treatments
  • Angiogenesis and VEGF in Cancer

Jun Ichi Abe has contributed to a range of scientific publications over recent years, some notable works include:

  • Revision of diagnostic guidelines for Kawasaki disease (6th revised edition), 2020, Pediatrics International
  • The Dual Role of High Endothelial Venules in Cancer Progression versus Immunity, 2020, Trends in Cancer
  • Multitier mechanics control stromal adaptations in the swelling lymph node, 2022, Nature Immunology
  • A divergent RWP-RK transcription factor determines mating type in heterothallic Closterium, 2022, New Phytologist
  • IL-1β and IL-17A are involved in IVIG resistance through activation of C/EBPβ and δ in a coronary artery model of Kawasaki disease, 2020, Allergy

The frequent co-authors collaborating with Jun Ichi Abe reflect a network of repeated scientific partnerships, including:

  • Jens V. Stein
  • Juliana Barreto de Albuquerque
  • Petra Pfenninger
  • Barbara Drašler
  • Bedia Begüm Karakoçak

In terms of publication venues, Jun Ichi Abe has disseminated research primarily through:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Immunology
  • Frontiers in Immunology
  • Pediatrics International
  • Trends in Cancer

The blend of medical and molecular biology approaches underpins Jun Ichi Abe's work, addressing fundamental mechanisms of immune cell behavior, disease pathogenesis, and cancer immunology. Their research contributes across both clinical and laboratory domains with a focus on diseases such as Kawasaki disease and cancer progression mediated by immune mechanisms.

Best Publications

  • Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase.

    Jun Ichi Abe;Masatoshi Kusuhara;Richard J. Ulevitch;Bradford C. Berk

  • Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms.

    Kimio Satoh;Patrizia Nigro;Tetsuya Matoba;Michael R. O'Dell

  • c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (BMK1)

    Jun Ichi Abe;Masafumi Takahashi;Mari Ishida;Jiing Dwan Lee

  • Reactive oxygen species as mediators of signal transduction in cardiovascular disease.

    Jun Ichi Abe;Bradford C. Berk

  • Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species

    Masanori Yoshizumi;Jun Ichi Abe;Judith Haendeler;Qunhua Huang

  • p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1.

    Eiichi Takáhashi;Jun Ichi Abe;Byron Gallis;Ruedi Aebersold

  • Endothelial Atheroprotective and Anti-inflammatory Mechanisms

    Bradford C. Berk;Jun Ichi Abe;Wang Min;James Surapisitchat

  • Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity

    Patrizia Nigro;Jun Ichi Abe;Bradford C. Berk

  • Fyn and JAK2 mediate Ras activation by reactive oxygen species.

    Jun Ichi Abe;Bradford C. Berk

  • Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism

    Kye Im Jeon;Xiangbin Xu;Toru Aizawa;Jae Hyang Lim

  • STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity.

    Yun Mao;Yun Mao;Yun Mao;Wei Luo;Wei Luo;Wei Luo;Lin Zhang;Lin Zhang;Weiwei Wu

  • Insulin-Like Growth Factor-1 Enhances Inflammatory Responses in Endothelial Cells: Role of Gab1 and MEKK3 in TNF-α–Induced c-Jun and NF-κB Activation and Adhesion Molecule Expression

    Wenyi Che;Nicole Lerner-Marmarosh;Qunhua Huang;Masaki Osawa

  • Cyclophilin A Mediates Vascular Remodeling by Promoting Inflammation and Vascular Smooth Muscle Cell Proliferation

    Kimio Satoh;Tetsuya Matoba;Jun Suzuki;Michael R. O'Dell

  • Functional Role of Phosphodiesterase 3 in Cardiomyocyte Apoptosis Implication in Heart Failure

    Bo Ding;Jun Ichi Abe;Heng Wei;Qunhua Huang

  • Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E–deficient mice

    Patrizia Nigro;Kimio Satoh;Kimio Satoh;Michael R. O'Dell;Nwe Nwe Soe

  • Radiation-Induced Endothelial Vascular Injury: A Review of Possible Mechanisms

    Bhanu Prasad Venkatesulu;Lakshmi Shree Mahadevan;Maureen L. Aliru;Xi Yang

  • Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains.

    Chen Yan;Honglin Luo;Jiing Dwan Lee;Jun ichi Abe

  • Role of Ca2+/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy

    Clint L. Miller;Masayoshi Oikawa;Yujun Cai;Andrew P. Wojtovich

  • Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras.

    Jun-ichi Abe;Masanori Okuda;Qunhua Huang;Masanori Yoshizumi

  • Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch.

    Yasuchika Takeishi;Qunhua Huang;Jun ichi Abe;Michael Glassman

Frequent Co-Authors

Bradford C. Berk
Bradford C. Berk University of Rochester
Chen Yan
Chen Yan University of Rochester
Keigi Fujiwara
Keigi Fujiwara The University of Texas MD Anderson Cancer Center
Jack Taunton
Jack Taunton University of California, San Francisco
Eugene B. Chang
Eugene B. Chang University of Chicago
Sunil Krishnan
Sunil Krishnan The University of Texas MD Anderson Cancer Center
Edward T.H. Yeh
Edward T.H. Yeh University of Missouri
Jian-Dong Li
Jian-Dong Li Georgia State University
Carlos A. Molina
Carlos A. Molina Montclair State University
James F. Martin
James F. Martin Baylor College of Medicine

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