World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
25940
World Ranking
6523
National Ranking
3035

Research.com Recognitions

  • 2003 - Fellow of Alfred P. Sloan Foundation

Overview

Jack Taunton is affiliated with the University of California, San Francisco in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Orthopedics and Sports Medicine, Organic Chemistry, Radiology, Nuclear Medicine and Imaging, and Cardiology and Cardiovascular Medicine.

The scientist's work contributes to several main topics, including:

  • Sports injuries and prevention
  • RNA and protein synthesis mechanisms
  • Click Chemistry and Applications
  • Sports Performance and Training
  • Monoclonal and Polyclonal Antibodies Research
  • RNA modifications and cancer
  • Peptidase Inhibition and Analysis

Jack Taunton has published frequently in various scientific venues. Their most common publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Chemical Biology
  • Journal of the American Chemical Society
  • Nature
  • Journal of Clinical Medicine

Among their recent papers are:

  • A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking, 2020, Journal of the American Chemical Society
  • Reversible lysine-targeted probes reveal residence time-based kinase selectivity, 2022, Nature Chemical Biology
  • mRNA decoding in human is kinetically and structurally distinct from bacteria, 2023, Nature
  • Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90, 2020, Journal of the American Chemical Society

The scientist has collaborated repeatedly with a group of frequent co-authors, including:

  • Darren E. R. Warburton
  • Gregory B. Craven
  • Jordan D. Carelli
  • Hao-Yuan Wang
  • Yanfei Guan

In 2003, Jack Taunton was recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p.

    Jack Taunton;Christian A. Hassig;Stuart L. Schreiber

  • Phase separation of signaling molecules promotes T cell receptor signal transduction

    Xiaolei Su;Xiaolei Su;Jonathon A. Ditlev;Jonathon A. Ditlev;Enfu Hui;Enfu Hui;Wenmin Xing;Wenmin Xing

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation

    Philippe P. Roux;David Shahbazian;Hieu Vu;Marina K. Holz

  • Structural bioinformatics-based design of selective, irreversible kinase inhibitors.

    Michael S. Cohen;Chao Zhang;Kevan M. Shokat;Jack Taunton

  • The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

    David Shahbazian;Philippe P Roux;Virginie Mieulet;Michael S Cohen

  • High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

    Fuqiang Chen;Shondra M Pruett-Miller;Yuping Huang;Monika Gjoka

  • Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

    Iana M Serafimova;Miles A Pufall;Miles A Pufall;Shyam Krishnan;Katarzyna Duda

  • Actin-Dependent Propulsion of Endosomes and Lysosomes by Recruitment of N-Wasp✪

    Jack Taunton;Brian A. Rowning;Margaret L. Coughlin;Michael Wu

  • Prolonged and tunable residence time using reversible covalent kinase inhibitors

    J Michael Bradshaw;Jesse M McFarland;Ville O Paavilainen;Angelina Bisconte

  • Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

    Priya S. Shah;Nichole Link;Gwendolyn M. Jang;Gwendolyn M. Jang;Phillip P. Sharp

  • Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

    Manojkumar A. Puthenveedu;Benjamin Lauffer;Paul Temkin;Rachel Vistein

  • Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes

    Qian Zhao;Xiaohu Ouyang;Xiaobo Wan;Ketan S. Gajiwala

  • Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway.

    Sang Wook Kang;Neena S. Rane;Soo Jung Kim;Jennifer L. Garrison

  • Cotranslocational Degradation Protects the Stressed Endoplasmic Reticulum from Protein Overload

    Seiichi Oyadomari;Chi Yun;Edward A. Fisher;Nicola Kreglinger

  • Covalent docking of large libraries for the discovery of chemical probes

    Nir London;Rand M Miller;Shyam Krishnan;Kenji Uchida

  • Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis.

    Shyam Krishnan;Rand M. Miller;Boxue Tian;R. Dyche Mullins

  • RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.

    Ulrik Doehn;Camilla Hauge;Scott R. Frank;Claus J. Jensen

  • Synthesis of Natural and Modified Trapoxins, Useful Reagents for Exploring Histone Deacetylase Function

    Jack Taunton;Jon L. Collins;Stuart L. Schreiber

Frequent Co-Authors

Ramanujan S. Hegde
Ramanujan S. Hegde MRC Laboratory of Molecular Biology
Jun Ichi Abe
Jun Ichi Abe The University of Texas MD Anderson Cancer Center
Keigi Fujiwara
Keigi Fujiwara The University of Texas MD Anderson Cancer Center
Venki Ramakrishnan
Venki Ramakrishnan MRC Laboratory of Molecular Biology
Brian K. Shoichet
Brian K. Shoichet University of California, San Francisco
Fadlo R. Khuri
Fadlo R. Khuri American University of Beirut
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Michael P. Doyle
Michael P. Doyle The University of Texas at San Antonio
Dong M. Shin
Dong M. Shin Emory University
Alma L. Burlingame
Alma L. Burlingame University of California, San Francisco

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