World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
121
Citations
68304
World Ranking
598
National Ranking
383

Chemistry

D-Index
121
Citations
68022
World Ranking
468
National Ranking
200

Brian K. Shoichet publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Brian K. Shoichet sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 535 publications — 90th percentile

90% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Brian K. Shoichet D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Brian K. Shoichet sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 121 D-Index — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Brian K. Shoichet is affiliated with the University of California, San Francisco in the United States. Their research spans multiple disciplines primarily within biochemistry, genetics, and molecular biology. A significant number of their publications focus on molecular biology, computational theory and mathematics, organic chemistry, infectious diseases, and cellular and molecular neuroscience.

Their work covers a range of specialized topics, including:

  • Computational Drug Discovery Methods
  • Receptor Mechanisms and Signaling
  • Protein Structure and Dynamics
  • SARS-CoV-2 and COVID-19 Research
  • Pharmacological Receptor Mechanisms and Effects
  • Chemical Synthesis and Analysis
  • Click Chemistry and Applications

Brian K. Shoichet has contributed to several recent scientific papers that highlight their involvement in studies related to SARS-CoV-2 as well as computational methods in drug discovery and receptor biology. Notable papers include:

  • The Global Phosphorylation Landscape of SARS-CoV-2 Infection (2020), published in Cell
  • A practical guide to large-scale docking (2021), published in Nature Protocols
  • A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing (2020), published in bioRxiv (Cold Spring Harbor Laboratory)
  • Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor (2020), published in Cell
  • Efficient Exploration of Chemical Space with Docking and Deep Learning (2021), published in Journal of Chemical Theory and Computation

The scientist frequently collaborates with several coauthors who have contributed to many joint publications, including John J. Irwin, Bryan L. Roth, Yurii S. Moroz, Stefan Gahbauer, and Xi-Ping Huang.

Their publications are often found in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Journal of Medicinal Chemistry
  • Science
  • Nature Chemical Biology

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • ZINC - A Free Database of Commercially Available Compounds for Virtual Screening

    John J. Irwin;Brian K. Shoichet

  • Relating protein pharmacology by ligand chemistry

    Michael J. Keiser;Bryan L. Roth;Bryan L. Roth;Blaine N. Armbruster;Paul R Ernsberger

  • Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking

    Michael M. Mysinger;Michael Carchia;John. J. Irwin;Brian K. Shoichet

  • Predicting new molecular targets for known drugs

    Michael J. Keiser;Vincent Setola;John J. Irwin;Christian Laggner

  • Virtual screening of chemical libraries.

    Brian K. Shoichet

  • Benchmarking sets for molecular docking.

    Niu Huang;Brian K. Shoichet;John J. Irwin

  • Automated docking with grid-based energy evaluation

    Elaine C. Meng;Brian K. Shoichet;Irwin D. Kuntz

  • A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

    Susan Lynne McGovern;Emilia Caselli;Emilia Caselli;Nikolaus Grigorieff;Brian K. Shoichet

  • The Global Phosphorylation Landscape of SARS-CoV-2 Infection.

    Mehdi Bouhaddou;Danish Memon;Bjoern Meyer;Kris M. White

  • Structure-based discovery of opioid analgesics with reduced side effects

    Aashish Manglik;Henry Lin;Dipendra K. Aryal;John D. McCorvy

  • Large-scale prediction and testing of drug activity on side-effect targets

    Eugen Lounkine;Michael J. Keiser;Steven Whitebread;Dmitri Mikhailov

  • Ultra-large library docking for discovering new chemotypes

    Jiankun Lyu;Sheng Wang;Trent E. Balius;Isha Singh

  • A relationship between protein stability and protein function.

    Brian K. Shoichet;Walter A. Baase;Ryota Kuroki;Brian W. Matthews

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • Prediction of protein-ligand interactions. Docking and scoring: successes and gaps.

    Andrew R Leach;Brian K Shoichet;Catherine E Peishoff

  • A specific mechanism of nonspecific inhibition.

    Susan Lynne McGovern;Brian T. Helfand;Brian Feng;Brian K. Shoichet

  • Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

    David E. Gordon;Joseph Hiatt;Mehdi Bouhaddou;Veronica V. Rezelj

  • Molecular Docking and High-Throughput Screening for Novel Inhibitors of Protein Tyrosine Phosphatase-1B

    Thompson N. Doman;Susan L. McGovern;Bryan J. Witherbee;Thomas P. Kasten

  • Lead discovery using molecular docking

    Brian K. Shoichet;Susan Lynne McGovern;Binqing Wei;John J. Irwin

Frequent Co-Authors

Bryan L. Roth
Bryan L. Roth University of North Carolina at Chapel Hill
Andrej Sali
Andrej Sali University of California, San Francisco
Frank M. Raushel
Frank M. Raushel Texas A&M University
Ken A. Dill
Ken A. Dill Stony Brook University
Xi Ping Huang
Xi Ping Huang University of North Carolina at Chapel Hill
Brian K. Kobilka
Brian K. Kobilka Stanford University
Irwin D. Kuntz
Irwin D. Kuntz University of California, San Francisco
Molly S. Shoichet
Molly S. Shoichet University of Toronto
Laszlo Urban
Laszlo Urban Novartis (Switzerland)
Richard Bonnet
Richard Bonnet University of Clermont Auvergne

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