World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
19548
World Ranking
5076
National Ranking
2430

Research.com Recognitions

  • 2004 - Hellman Fellow

Overview

Jay T. Groves is affiliated with the University of California, Berkeley in the United States. Their research spans multiple domains within life sciences, with a focus on biochemistry, genetics, and molecular biology, as well as immunology and microbiology and medicine.

Their work has been published extensively in several research venues. Frequent publication outlets include:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • eLife
  • Communications Biology

Key areas of study in their research encompass molecular biology, immunology, oncology, cell biology, and radiology, nuclear medicine, and imaging. Specifically, the subfields they contribute to the most are:

  • Molecular Biology
  • Immunology
  • Oncology
  • Cell Biology
  • Radiology, Nuclear Medicine and Imaging

Main topics covered in Jay T. Groves's publications include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Protein Kinase Regulation and GTPase Signaling
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research
  • RNA Research and Splicing
  • Receptor Mechanisms and Signaling

The following are some of their recent scientific papers, detailing the research focus and venue of publication:

  • "A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane," 2022, Proceedings of the National Academy of Sciences
  • "Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions," 2020, Biophysical Journal
  • "Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation," 2020, eLife
  • "How the T cell signaling network processes information to discriminate between self and agonist ligands," 2020, Proceedings of the National Academy of Sciences
  • "Raf promotes dimerization of the Ras G-domain with increased allosteric connections," 2021, Proceedings of the National Academy of Sciences

Jay T. Groves has collaborated frequently with other researchers in the field. Notable co-authors include:

  • Kiera B. Wilhelm
  • Darren B. McAffee
  • John Kuriyan
  • Shumpei Morita
  • Mark K. O'Dair

In 2004, Jay T. Groves received the Hellman Fellow award. This recognition is part of their professional record within the scientific community.

Best Publications

  • Micropatterning fluid lipid bilayers on solid supports.

    Jay T. Groves;Nick Ulman;Steven G. Boxer

  • TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

    Björn F Lillemeier;Manuel A Mörtelmaier;Martin B Forstner;Martin B Forstner;Johannes B Huppa

  • Altered TCR signaling from geometrically repatterned immunological synapses.

    Kaspar D. Mossman;Gabriele Campi;Jay T. Groves;Jay T. Groves;Michael L. Dustin

  • Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor.

    Nicholas F. Endres;Rahul Das;Rahul Das;Adam W. Smith;Adam W. Smith;Anton Arkhipov

  • mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding

    M. Delarue;G.P. Brittingham;S. Pfeffer;I.V. Surovtsev;I.V. Surovtsev

  • Micropattern formation in supported lipid membranes.

    Jay T. Groves;Steven G. Boxer

  • Restriction of Receptor Movement Alters Cellular Response: Physical Force Sensing by EphA2

    Khalid Salaita;Pradeep M. Nair;Pradeep M. Nair;Rebecca S. Petit;Rebecca S. Petit;Richard M. Neve

  • Synaptic pattern formation during cellular recognition

    S. Y. Qi;Jay T. Groves;Arup K. Chakraborty

  • Architecture and Function of Membrane Proteins in Planar Supported Bilayers: A Study with Photosynthetic Reaction Centers†

    Joshua Salafsky;Jay T. Groves;Steven G. Boxer

  • Supported planar bilayers in studies on immune cell adhesion and communication.

    Jay T. Groves;Michael L. Dustin

  • Structural characterization of horseradish peroxidase using EXAFS spectroscopy: evidence for Fe=O ligation in compounds I and II

    James E. Penner-Hahn;Kim. Smith Eble;Thomas J. McMurry;Mark. Renner

  • Engineering of a synthetic electron conduit in living cells

    Heather M. Jensen;Aaron E. Albers;Konstantin R. Malley;Yuri Y. Londer

  • Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

    Leah V. Sibener;Ricardo A. Fernandes;Elizabeth M. Kolawole;Catherine B. Carbone

  • Membrane-dependent signal integration by the Ras activator Son of sevenless

    Jodi Gureasko;William J Galush;Sean Boykevisch;Holger Sondermann;Holger Sondermann

  • Curvature-Modulated Phase Separation in Lipid Bilayer Membranes

    Raghuveer Parthasarathy;Cheng-Han Yu;Jay T. Groves

  • A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.

    William Y. C. Huang;Steven Alvarez;Yasushi Kondo;Yasushi Kondo;Young Kwang Lee

  • Molecular mechanisms in signal transduction at the membrane

    Jay T Groves;John Kuriyan

  • A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

    Luke H. Chao;Margaret M. Stratton;Il-Hyung Lee;Il-Hyung Lee;Oren S. Rosenberg

  • Detection of molecular interactions at membrane surfaces through colloid phase transitions

    Michael M. Baksh;Michael M. Baksh;Michal Jaros;Jay T. Groves;Jay T. Groves

  • Erratum: TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation (Nature Immunology (2010) 11 (90-96))

    Björn F. Lillemeier;Manuel A. Mörtelmaier;Martin B. Forstner;Johannes B. Huppa

Frequent Co-Authors

John Kuriyan
John Kuriyan Vanderbilt University
Steven G. Boxer
Steven G. Boxer Stanford University
Michael L. Dustin
Michael L. Dustin University of Oxford
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Lars Iversen
Lars Iversen Aarhus University Hospital
Howard Schulman
Howard Schulman Stanford University
Michael P. Sheetz
Michael P. Sheetz The University of Texas Medical Branch at Galveston
Arthur Weiss
Arthur Weiss University of California, San Francisco
Nam-Joon Cho
Nam-Joon Cho Nanyang Technological University

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