World's Best Scientists 2026 revealed!
Arup K. Chakraborty

Arup K. Chakraborty

D-Index & Metrics

Chemistry

D-Index
69
Citations
21237
World Ranking
6100
National Ranking
1857

Biology and Biochemistry

D-Index
75
Citations
24866
World Ranking
5240
National Ranking
2493

Research.com Recognitions

  • 2018 - Fellow of John Simon Guggenheim Memorial Foundation
  • 2016 - Member of the National Academy of Sciences
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2007 - Fellow of the American Academy of Arts and Sciences
  • 2004 - Member of the National Academy of Engineering For the application of theoretical chemistry to practical problems, including immune system recognition, polymer interfaces, sensor technology, and catalysis.

Overview

Arup K. Chakraborty is affiliated with MIT in the United States and specializes in research spanning Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Their work has contributed to multiple subfields including Molecular Biology, Immunology, Infectious Diseases, Epidemiology, and Radiology, Nuclear Medicine, and Imaging.

The scientist's research covers a range of topics, notably:

  • Vaccines and immunoinformatics approaches
  • T-cell and B-cell Immunology
  • SARS-CoV-2 and COVID-19 Research
  • RNA Research and Splicing
  • Monoclonal and Polyclonal Antibodies Research
  • Immunotherapy and Immune Responses
  • RNA and protein synthesis mechanisms

Among their recent papers are:

  • "RNA-Mediated Feedback Control of Transcriptional Condensates" (2020), published in Cell
  • "Partitioning of cancer therapeutics in nuclear condensates" (2020), published in Science
  • "RNA in formation and regulation of transcriptional condensates" (2021), published in RNA
  • "An integrated flood risk assessment approach based on coupled hydrological-hydraulic modeling and bottom-up hazard vulnerability analysis" (2021), published in Environmental Modelling & Software
  • "Defining and Manipulating B Cell Immunodominance Hierarchies to Elicit Broadly Neutralizing Antibody Responses against Influenza Virus" (2020), published in Cell Systems

Their frequent co-authors include:

  • Mehran Kardar
  • Deepti Kannan
  • Pradeep Natarajan
  • Eric Wang
  • Krishna Shrinivas

Publication venues where they have contributed the most frequently are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Cell
  • Cell Reports

The scientist has been recognized by several awards including:

  • Fellow of John Simon Guggenheim Memorial Foundation (2018)
  • Member of the National Academy of Sciences (2016)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2008)
  • Fellow of the American Academy of Arts and Sciences (2007)
  • Member of the National Academy of Engineering (2004) for the application of theoretical chemistry to practical problems including immune system recognition, polymer interfaces, sensor technology, and catalysis

Best Publications

  • Advances in methods and algorithms in a modern quantum chemistry program package

    Yihan Shao;Laszlo Fusti Molnar;Yousung Jung;Jörg Kussmann

  • Coactivator condensation at super-enhancers links phase separation and gene control

    Benjamin R. Sabari;Alessandra Dall’Agnese;Ann Boija;Isaac A. Klein;Isaac A. Klein

  • A Phase Separation Model for Transcriptional Control.

    Denes Hnisz;Krishna Shrinivas;Richard A. Young;Arup K. Chakraborty

  • Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

    Dan H. Barouch;James B. Whitney;Brian Moldt;Florian Klein

  • Origin of nanomechanical cantilever motion generated from biomolecular interactions.

    Guanghua Wu;Haifeng Ji;Karolyn Hansen;Thomas Thundat

  • The immunological synapse balances T cell receptor signaling and degradation.

    Kyeong-Hee Lee;Kyeong-Hee Lee;Aaron R. Dinner;Chun Tu;Gabriele Campi

  • RNA-Mediated Feedback Control of Transcriptional Condensates.

    Jonathan E. Henninger;Ozgur Oksuz;Krishna Shrinivas;Krishna Shrinivas;Ido Sagi

  • T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

    Sarah E Henrickson;Thorsten R Mempel;Irina B Mazo;Bai Liu

  • Partitioning of Cancer Therapeutics in Nuclear Condensates

    Isaac A. Klein;Isaac A. Klein;Ann Boija;Lena K. Afeyan;Susana Wilson Hawken

  • Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

    Hugo Mouquet;Johannes F. Scheid;Johannes F. Scheid;Markus J. Zoller;Michelle Krogsgaard

  • Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells

    Jayajit Das;Mary Ho;Julie Zikherman;Christopher Govern

  • Insights into the initiation of TCR signaling

    Arup K Chakraborty;Arthur Weiss

  • A growing string method for determining transition states: Comparison to the nudged elastic band and string methods

    Baron G Peters;Andreas Heyden;Alexis T. Bell;Arup Chakraborty

  • Synaptic pattern formation during cellular recognition

    S. Y. Qi;Jay T. Groves;Arup K. Chakraborty

  • Enhancer features that drive formation of transcriptional condensates

    Krishna Shrinivas;Benjamin R. Sabari;Eliot L. Coffey;Isaac A. Klein

  • Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

    Hok Hei Tam;Mariane B. Melo;Myungsun Kang;Jeisa M. Pelet

  • Enhanced clearance of HIV-1–infected cells by broadly neutralizing antibodies against HIV-1 in vivo

    Ching-Lan Lu;Ching-Lan Lu;Dariusz K. Murakowski;Stylianos Bournazos;Till Schoofs

  • Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

    Andrej Košmrlj;Andrej Košmrlj;Elizabeth L. Read;Elizabeth L. Read;Ying Qi;Todd M. Allen

  • Understanding the Structure and Function of the Immunological Synapse

    Michael L. Dustin;Arup K. Chakraborty;Andrey S. Shaw

  • CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse.

    Qi-Jing Li;Aaron R Dinner;Aaron R Dinner;Shuyan Qi;Darrell J Irvine;Darrell J Irvine

Frequent Co-Authors

Alexis T. Bell
Alexis T. Bell University of California, Berkeley
Bruce D. Walker
Bruce D. Walker Harvard University
Arthur Weiss
Arthur Weiss University of California, San Francisco
Nitash P. Balsara
Nitash P. Balsara University of California, Berkeley
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Maxim N. Artyomov
Maxim N. Artyomov Washington University in St. Louis
Jay T. Groves
Jay T. Groves University of California, Berkeley
Eugene I. Shakhnovich
Eugene I. Shakhnovich Harvard University

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