Michael K. Rosen

Research.com Recognitions

• 2020 - Member of the National Academy of Sciences

Overview

Best Publications

• Biomolecular condensates: organizers of cellular biochemistry

  Salman F Banani;Hyun-Ok Kate Lee;Anthony Hyman;Michael K Rosen

  4805
  Citations

• Phase transitions in the assembly of multivalent signalling proteins

  Pilong Li;Sudeep Banjade;Hui Chun Cheng;Soyeon Kim

  2651
  Citations

• Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

  Yuan Lin;David S.W. Protter;Michael K. Rosen;Michael K. Rosen;Michael K. Rosen;Roy Parker;Roy Parker;Roy Parker

  1496
  Citations

• Phase separation of signaling molecules promotes T cell receptor signal transduction

  Xiaolei Su;Xiaolei Su;Jonathon A. Ditlev;Jonathon A. Ditlev;Enfu Hui;Enfu Hui;Wenmin Xing;Wenmin Xing

  1273
  Citations

• Compositional Control of Phase-Separated Cellular Bodies

  Salman F. Banani;Allyson M. Rice;William B. Peeples;Yuan Lin

  1133
  Citations

• Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.

  Annette S. Kim;Lazaros T. Kakalis;Norzehan Abdul-Manan;Grace A. Liu

  950
  Citations

• Organization of Chromatin by Intrinsic and Regulated Phase Separation

  Bryan A. Gibson;Lynda K. Doolittle;Maximillian W.G. Schneider;Liv E. Jensen

  880
  Citations

• Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein

  Chi W. Pak;Martyna Kosno;Alex S. Holehouse;Shae B. Padrick

  717
  Citations

• Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins.

  Tyler S Harmon;Alex S Holehouse;Michael K Rosen;Rohit V Pappu

  633
  Citations

• A framework for understanding the functions of biomolecular condensates across scales.

  Andrew S. Lyon;William B. Peeples;Michael K. Rosen

  630
  Citations

• Phase transitions of multivalent proteins can promote clustering of membrane receptors

  Sudeep Banjade;Michael K Rosen

  553
  Citations

• Structure and control of the actin regulatory WAVE complex

  Zhucheng Chen;Dominika Borek;Shae B. Padrick;Timothy S. Gomez

  534
  Citations

• Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

  Koenraad Devriendt;Annette S. Kim;Gert Mathijs;Suzanna G M Frints

  483
  Citations

• Structural Basis for Relief of Autoinhibition of the Dbl Homology Domain of Proto-Oncogene Vav by Tyrosine Phosphorylation

  Behzad Aghazadeh;William E. Lowry;Xin Yun Huang;Michael K. Rosen;Michael K. Rosen

  476
  Citations

• Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

  Takanori Otomo;Diana R. Tomchick;Chinatsu Otomo;Sanjay C. Panchal

  468
  Citations

• Solution structure of the SH3 domain of Src and identification of its ligand-binding site

  Hongtao Yu;Michael K. Rosen;Tae Bum Shin;Cynthia Seidel-Dugan

  448
  Citations

• Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.

  Norzehan Abdul-Manan;Behzad Aghazadeh;Behzad Aghazadeh;Grace A. Liu;Ananya Majumdar

  435
  Citations

• Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

  Lindsay B. Case;Lindsay B. Case;Xu Zhang;Jonathon A. Ditlev;Jonathon A. Ditlev;Michael K. Rosen;Michael K. Rosen

  414
  Citations

• Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.

  Stephen W. Michnick;Michael K. Rosen;Thomas J. Wandless;Martin Karplus

  381
  Citations

• Selective Methyl Group Protonation of Perdeuterated Proteins

  Michael K. Rosen;Michael K. Rosen;Kevin H. Gardner;Randall C. Willis;Wendy E. Parris

  373
  Citations