Diana R. Tomchick

What is she best known for?

The fields of study she is best known for:

• Enzyme
• Gene
• Amino acid

Her primary areas of study are Cell biology, Protein structure, Biochemistry, Stereochemistry and Biophysics. She has researched Cell biology in several fields, including Mad2, Mitotic checkpoint complex, CDC20 and Mad2 Proteins. Her Protein structure research is multidisciplinary, incorporating perspectives in Clathrin, Peptide sequence, Actin, Ankyrin repeat and Binding site.

Her work on Demethylase, Ankyrin and Arabidopsis as part of general Biochemistry research is often related to Histone methylation and L1 family, thus linking different fields of science. Her Stereochemistry research incorporates themes from Oxidoreductase, Amidophosphoribosyltransferase, Penicillin amidase, Cysteine and Nucleophile. In general Biophysics, her work in Molecular motor and Myosin is often linked to MYL2, Smooth Muscle Myosins and Meromyosin linking many areas of study.

Her most cited work include:

• Three-dimensional structure of myosin subfragment-1: a molecular motor (1744 citations)
• Three-dimensional structure of myosin subfragment-1: a molecular motor (1744 citations)
• A protein catalytic framework with an N-terminal nucleophile is capable of self-activation (530 citations)

What are the main themes of her work throughout her whole career to date?

Diana R. Tomchick mostly deals with Biochemistry, Cell biology, Biophysics, Protein structure and Stereochemistry. Diana R. Tomchick connects Biochemistry with Treponema in her research. Her Cell biology study combines topics from a wide range of disciplines, such as Spindle checkpoint and Mad2.

Her Biophysics study incorporates themes from Membrane, Synaptotagmins and Synaptotagmin 1. Her Protein structure research incorporates elements of Histidine kinase, Peptide sequence, Molecular biology and Actin. As part of the same scientific family, Diana R. Tomchick usually focuses on Stereochemistry, concentrating on Decarboxylation and intersecting with Cofactor.

She most often published in these fields:

• Biochemistry (41.61%)
• Cell biology (27.95%)
• Biophysics (23.60%)

What were the highlights of her more recent work (between 2017-2021)?

• Cell biology (27.95%)
• Biophysics (23.60%)
• Effector (7.45%)

In recent papers she was focusing on the following fields of study:

Diana R. Tomchick focuses on Cell biology, Biophysics, Effector, Biochemistry and Pore complex. Many of her studies on Cell biology apply to Protein AMPylation as well. Her Cryo-electron microscopy study in the realm of Biophysics connects with subjects such as High resolution.

The concepts of her Effector study are interwoven with issues in Transport protein, Protein subunit and Protein kinase A. Diana R. Tomchick works mostly in the field of Protein kinase A, limiting it down to topics relating to Kinase activity and, in certain cases, Structural biology, Protein phosphorylation, Allosteric regulation and Peptide sequence. Her work on Enzyme structure, Binding site and Heterotetramer is typically connected to Deoxyhypusine synthase and Eukaryotic initiation factor as part of general Biochemistry study, connecting several disciplines of science.

Between 2017 and 2021, her most popular works were:

• Protein AMPylation by an Evolutionarily Conserved Pseudokinase. (73 citations)
• Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases (52 citations)
• Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes. (49 citations)

In her most recent research, the most cited papers focused on:

• Enzyme
• Gene
• Amino acid

Her scientific interests lie mostly in Cell biology, Point mutation, Chaperone, Biochemistry and Membrane. Her work on Protein kinase A, Phosphorylation and Kinase as part of general Cell biology study is frequently linked to Karyopherin, bridging the gap between disciplines. Her Point mutation research includes elements of Drug resistance and Dihydroorotate dehydrogenase.

Her work on EIF5A, Trypanosoma brucei and Heterotetramer as part of general Biochemistry study is frequently connected to Hypusine and Deoxyhypusine synthase, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. Her Membrane research integrates issues from Dodecameric protein, Biophysics, Cryo-electron microscopy and Protein family. Her research integrates issues of Cholesterol and Intracellular in her study of Biophysics.