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Microbiology

D-Index
59
Citations
14342
World Ranking
3242
National Ranking
1282

Overview

Michael V. Norgard is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans multiple fields of study, including Medicine and Immunology and Microbiology, with a focus on several subfields such as Physiology, Virology, Hematology, Epidemiology, and Oncology.

The main topics of their work encompass:

  • Syphilis Diagnosis and Treatment
  • HIV Research and Treatment
  • Blood groups and transfusion
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Peptidase Inhibition and Analysis
  • Protein Structure and Dynamics
  • Mass Spectrometry Techniques and Applications

Their recent publications include:

  • "Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum," 2020, mBio
  • "Using modern approaches to sedimentation velocity to detect conformational changes in proteins," 2020, European Biophysics Journal
  • "Inhibition of bacterial FMN transferase: A potential avenue for countering antimicrobial resistance," 2021, Protein Science
  • "Biophysical and biochemical studies support TP0094 as a phosphotransacetylase in an acetogenic energy-conservation pathway in Treponema pallidum," 2023, PLoS ONE
  • "An rfuABCD-Like Operon and Its Relationship to Riboflavin Utilization and Mammalian Infectivity by Borrelia burgdorferi," 2021, Infection and Immunity

Frequent coauthors in their work include:

  • Ranjit K. Deka
  • Wei Z. Liu
  • Chad A. Brautigam
  • Akanksha Deka
  • Shih-Chia Tso

Michael V. Norgard has contributed to publications in the following venues:

  • mBio
  • Protein Science
  • PLoS ONE
  • European Biophysics Journal
  • Infection and Immunity

Best Publications

  • Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.

    Hans D. Brightbill;Daniel H. Libraty;Stephan R. Krutzik;Ruey Bing Yang

  • Induction of Direct Antimicrobial Activity Through Mammalian Toll-Like Receptors

    Sybille Thoma-Uszynski;Steffen Stenger;Osamu Takeuchi;Maria Teresa Ochoa

  • The Lyme disease agent exploits a tick protein to infect the mammalian host

    Nandhini Ramamoorthi;Sukanya Narasimhan;Utpal Pal;Fukai Bao

  • Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2.

    Cheryl J. Hertz;Sylvia M. Kiertscher;Paul J. Godowski;Deborah A. Bouis

  • DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete

    Andrew T. Revel;Adel M. Talaat;Michael V. Norgard

  • Activation and regulation of Toll-like receptors 2 and 1 in human leprosy.

    Stephan R. Krutzik;Maria Teresa Ochoa;Peter A. Sieling;Satoshi Uematsu

  • OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

    Utpal Pal;Xiaofeng Yang;Manchuan Chen;Linda K. Bockenstedt

  • Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN–RpoS regulatory pathway

    Anette Hübner;Xiaofeng Yang;Dena M. Nolen;Taissia G. Popova

  • Essential Role for OspA/B in the Life Cycle of the Lyme Disease Spirochete

    Xiaofeng F. Yang;Utpal Pal;Sophie M. Alani;Erol Fikrig

  • Treponema pallidum , the syphilis spirochete: making a living as a stealth pathogen

    Justin D. Radolf;Ranjit K. Deka;Arvind Anand;David Šmajs

  • Activation of Toll-Like Receptor 2 on Human Dendritic Cells Triggers Induction of IL-12, But Not IL-10

    Sybille Thoma-Uszynski;Sylvia M. Kiertscher;Maria Teresa Ochoa;Deborah A. Bouis

  • Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi.

    Xiaofeng Yang;Martin S. Goldberg;Taissia G. Popova;George B. Schoeler

  • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide

    Timothy J. Sellati;Deborah A. Bouis;Richard L. Kitchens;Richard P. Darveau;Richard P. Darveau

  • A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state.

    Darrin R. Akins;Kenneth W. Bourell;Melissa J. Caimano;Michael V. Norgard

  • TREPONEMA PALLIDUM AND BORRELIA BURGDORFERI LIPOPROTEINS AND SYNTHETIC LIPOPEPTIDES ACTIVATE MONOCYTES/MACROPHAGES

    J. D. Radolf;L. L. Arndt;D. R. Akins;L. L. Curetty

  • The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi

    Xiaofeng F. Yang;Sophie M. Alani;Michael V. Norgard

  • Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone.

    Yong-Hwan Lee;Ranjit K. Deka;Michael V. Norgard;Justin D. Radolf

  • Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue.

    Darrin R. Akins;Stephen F. Porcella;Taissia G. Popova;Dmitriy Shevchenko

  • Central nervous system infection in congenital syphilis

    Ian C. Michelow;George D. Wendel;Michael V. Norgard;Fiker Zeray

  • Transcriptional interplay among the regulators Rrp2, RpoN and RpoS in Borrelia burgdorferi.

    Zhiming Ouyang;Jon S. Blevins;Michael V. Norgard

Frequent Co-Authors

Chad A. Brautigam
Chad A. Brautigam The University of Texas Southwestern Medical Center
Justin D. Radolf
Justin D. Radolf University of Connecticut Health Center
Diana R. Tomchick
Diana R. Tomchick The University of Texas Southwestern Medical Center
Mischa Machius
Mischa Machius The University of Texas Southwestern Medical Center
Utpal Pal
Utpal Pal University of Maryland, College Park
Melissa J. Caimano
Melissa J. Caimano University of Connecticut Health Center
Robert L. Modlin
Robert L. Modlin University of California, Los Angeles
Erol Fikrig
Erol Fikrig Yale University
James A. Richardson
James A. Richardson The University of Texas Southwestern Medical Center

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