World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
71
Citations
20517
World Ranking
2184
National Ranking
989

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Laura P.W. Ranum is affiliated with the University of Florida in the United States. Their research primarily spans several interconnected fields, including Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine. Within these disciplines, the scientist focuses on subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Neurology, Genetics, and Cell Biology.

The main topics of their research cover Genetic Neurodegenerative Diseases, RNA Research and Splicing, Mitochondrial Function and Pathology, Amyotrophic Lateral Sclerosis Research, RNA Regulation and Disease, Prion Diseases and Protein Misfolding, and Neurological Disorders and Treatments.

Their recent scientific publications include:

  • Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice, 2020, Proceedings of the National Academy of Sciences
  • Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice, 2022, Neuron
  • Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs, 2020, Neuron
  • CCG•CGG interruptions in high-penetrance SCA8 families increase RAN translation and protein toxicity, 2021, EMBO Molecular Medicine
  • The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG•CAGG repeats, 2021, Human Molecular Genetics

Laura P.W. Ranum has collaborated frequently with several coauthors, including Tao Zu, Shu Guo, Lien Nguyen, Mónica Báñez-Coronel, and John D. Cleary.

Their research output appears predominantly in the following publication venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • Proceedings of the National Academy of Sciences
  • Human Molecular Genetics
  • EMBO Molecular Medicine

The scientist was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2016.

Best Publications

  • Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.

    Harry T. Orr;Ming yi Chung;Sandro Banfi;Thomas J. Kwiatkowski

  • Myotonic Dystrophy Type 2 Caused by a CCTG Expansion in Intron 1 of ZNF9

    Christina L. Liquori;Kenneth Ricker;Melinda L. Moseley;Jennifer F. Jacobsen

  • Non-ATG–initiated translation directed by microsatellite expansions

    Tao Zu;Brian Gibbens;Noelle S. Doty;Mário Gomes-Pereira

  • RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia

    Tao Zu;Yuanjing Liu;Monica Bañez-Coronel;Tammy Reid

  • An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8)

    Michael D. Koob;Melinda L. Moseley;Lawrence J. Schut;Kellie A. Benzow

  • Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I

    Ming Yi Chung;Laura P.W. Ranum;Lisa A. Duvick;Antonio Servadio

  • RNA-mediated neuromuscular disorders.

    Laura P W Ranum;Thomas A Cooper

  • Myotonic dystrophy type 2 Molecular, diagnostic and clinical spectrum

    J W Day;Kenneth Ricker;J F Jacobsen;L J Rasmussen

  • Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8

    Melinda L Moseley;Tao Zu;Yoshio Ikeda;Wangcai Gao

  • Spectrin mutations cause spinocerebellar ataxia type 5

    Yoshio Ikeda;Katherine A Dick;Marcy R Weatherspoon;Dan Gincel

  • Spinocerebellar ataxia type 5 in a family descended from the grandparents of President Lincoln maps to chromosome 11.

    Laura P.W. Ranum;Lawrence J. Schut;Julie K. Lundgren;Harry T. Orr

  • C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD

    Yuanjing Liu;Amrutha Pattamatta;Tao Zu;Tammy Reid

  • RAN Translation in Huntington Disease

    Monica Bañez-Coronel;Fatma Ayhan;Alex D. Tarabochia;Tao Zu

  • Genetic mapping of a second myotonic dystrophy locus

    Laura P. W. Ranum;Paul F. Rasmussen;Kellie A. Benzow;Michael D. Koob

  • Mutant Huntingtin Disrupts the Nuclear Pore Complex

    Jonathan C. Grima;J. Gavin Daigle;Nicolas Arbez;Kathleen C. Cunningham

  • RNA gain-of-function in spinocerebellar ataxia type 8.

    Randy S. Daughters;Daniel L. Tuttle;Wangcai Gao;Yoshio Ikeda

  • Isolation and characterization of the nitrate reductase structural gene of Chlamydomonas reinhardtii.

    Emilio Fernandez;Rogene Schnell;Laura P. W. Ranum;Susanne C. Hussey

  • Correlating phenotype and genotype in the periodic paralyses

    T. M. Miller;M. R. Dias da Silva;H. A. Miller;H. Kwiecinski

  • New nomenclature and DNA testing guidelines for myotonic dystrophy type 1 (DM1)

    T. Ashizawa;I. Gonzales;N. Ohsawa;R. H. Singer

  • Myotonic Dystrophy: RNA Pathogenesis Comes into Focus

    Laura P.W. Ranum;John W. Day

Frequent Co-Authors

Harry T. Orr
Harry T. Orr University of Minnesota
Maurice S. Swanson
Maurice S. Swanson University of Florida
Thomas D. Bird
Thomas D. Bird University of Washington
Huda Y. Zoghbi
Huda Y. Zoghbi Baylor College of Medicine
Benedikt Schoser
Benedikt Schoser Ludwig-Maximilians-Universität München
Tetsuo Ashizawa
Tetsuo Ashizawa Houston Methodist
Shoji Tsuji
Shoji Tsuji University of Tokyo
Juan C. Troncoso
Juan C. Troncoso Johns Hopkins University School of Medicine
Olaf Riess
Olaf Riess University of Tübingen
Alexis Brice
Alexis Brice Institut du Cerveau

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you are interested in Genetics but want to explore related career options in healthcare, there are many flexible and affordable online degrees available. For those looking at entry-level roles, a low cost medical coding and billing online program offers a fast route into the administrative side of healthcare, allowing you to play a vital role in hospitals and clinics.

Nursing is always in demand, and several easy nursing colleges to get into can help you quickly begin a hands-on healthcare career. If you’re interested in leadership or management, there are options for a healthcare administration degrees that can be completed faster through accelerated programs.

Those seeking to balance affordability and flexibility might consider health administration degrees online, which allow learning at your own pace while preparing for roles in hospital oversight, data management, and public health.

Whichever you choose, these programs can complement a background in genetics and open diverse career pathways within the healthcare sector.

Best Scientists Citing Laura P.W. Ranum

Trending Scientists

Recently Published Articles