Charles A. Thornton

Overview

Best Publications

• Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

  Jill W. Miller;Carl R. Urbinati;Patana Teng-umnuay;Myrna G. Stenberg

  1050
  Citations

• A muscleblind knockout model for myotonic dystrophy.

  Rahul N. Kanadia;Karen A. Johnstone;Ami Mankodi;Codrin Lungu

  825
  Citations

• Expanded CUG Repeats Trigger Aberrant Splicing of ClC-1 Chloride Channel Pre-mRNA and Hyperexcitability of Skeletal Muscle in Myotonic Dystrophy

  Ami Mankodi;Masanori P. Takahashi;Hong Jiang;Carol L. Beck

  811
  Citations

• Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

  Hong Jiang;Ami Mankodi;Maurice S. Swanson;Richard T. Moxley

  570
  Citations

• Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

  Xiaoyan Lin;Jill W. Miller;Ami Mankodi;Rahul N. Kanadia

  569
  Citations

• Targeting nuclear RNA for in vivo correction of myotonic dystrophy

  Thurman M. Wheeler;Andrew J. Leger;Sanjay K. Pandey;A. Robert MacLeod

  546
  Citations

• Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2

  Ami Mankodi;Carl R. Urbinati;Qiu-Ping Yuan;Richard T Moxley

  505
  Citations

• Gene expression profile of aging in human muscle

  Stephen Welle;Andrew I Brooks;Joseph M Delehanty;Nancy Needler

  497
  Citations

• Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA

  Thurman M. Wheeler;Krzysztof Sobczak;John D. Lueck;Robert J. Osborne

  429
  Citations

• Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.

  Rahul N. Kanadia;Jihae Shin;Yuan Yuan;Stuart G. Beattie

  404
  Citations

• Myofibrillar protein synthesis in young and old men

  S. Welle;C. Thornton;R. Jozefowicz;M. Statt

  392
  Citations

• Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy

  Hongqing Du;Melissa S Cline;Robert J Osborne;Daniel L Tuttle

  374
  Citations

• Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.

  Susan A. M. Mulders;Walther J. A. A. van den Broek;Thurman M. Wheeler;Huib J. E. Croes

  371
  Citations

• Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes

  Charles A. Thornton;Keith Johnson;Richard T. Moxley

  363
  Citations

• Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy.

  J. R. Mendell;R. J. Barohn;M. L. Freimer;J. T. Kissel

  355
  Citations

• Effect of age on muscle hypertrophy induced by resistance training

  Stephen Welle;Saara Totterman;Charles Thornton

  307
  Citations

• Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

  Thurman M. Wheeler;John D. Lueck;Maurice S. Swanson;Robert T. Dirksen

  306
  Citations

• Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene

  Charles A. Thornton;James P. Wymer;Zachary Simmons;Carolyn McClain

  303
  Citations

• Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

  Ranjan Batra;Konstantinos Charizanis;Mini Manchanda;Apoorva Mohan

  300
  Citations

• RNA-dominant diseases

  Robert J. Osborne;Charles A. Thornton

  298
  Citations