His scientific interests lie mostly in Cell biology, Apoptosis, Immunology, Osteoclast and Molecular biology. His Cell biology research is multidisciplinary, incorporating perspectives in Caspase 3, Cellular differentiation, APAF1 and T-cell receptor. His Immunology research is multidisciplinary, relying on both Osteoprotegerin and Signal transduction.
His Osteoprotegerin research integrates issues from Periodontitis, Lymphocyte and Osteoimmunology, RANKL. His study in Osteoclast is interdisciplinary in nature, drawing from both Endocrinology, Bone remodeling and CD8. His studies in Molecular biology integrate themes in fields like Complementation, Cytotoxic T cell, Nuclear protein, NFATC Transcription Factors and Transcription.
His main research concerns Cell biology, Immunology, Molecular biology, Notch signaling pathway and Cancer research. His Cell biology study combines topics in areas such as Apoptosis, Ubiquitin ligase, Cellular differentiation and Cell growth. His study looks at the relationship between Immunology and topics such as In vivo, which overlap with In vitro and Immune system.
In his study, NFATC Transcription Factors, Nuclear protein, Complementation and Lymphocyte proliferation is inextricably linked to Transcription, which falls within the broad field of Molecular biology. His work deals with themes such as Osteoprotegerin, RANKL, RANK Ligand and Downregulation and upregulation, which intersect with Cancer research. He combines subjects such as Endocrinology, Bone remodeling, Lymphocyte and Osteoimmunology with his study of RANK Ligand.
Young-Yun Kong mainly investigates Cell biology, Internal medicine, Stem cell, Hormone and Endocrinology. His research integrates issues of Apoptosis and Autocrine signalling in his study of Cell biology. His work on Senescence as part of general Internal medicine study is frequently connected to Hypothalamic–pituitary–gonadal axis, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His Stem cell research is multidisciplinary, incorporating elements of Anatomy, LRP6, Bioinformatics and LRP5. His Hormone research includes elements of Progenitor cell and Genetically modified mouse. His Endocrinology study incorporates themes from Juvenile, Satellite, Regeneration and Adult stem cell.
Young-Yun Kong spends much of his time researching Cell growth, Carcinogenesis, Stem cell, Cell biology and Phosphorylation. His biological study spans a wide range of topics, including Reactive oxygen species and Knockout mouse. His Carcinogenesis research includes themes of Wnt signaling pathway, LRP5, Angiogenesis, Autocrine signalling and Apoptosis.
His Stem cell research incorporates elements of Hormone, Internal medicine, Regeneration, LRP6 and Satellite. His biological study focuses on Signal transduction. Young-Yun Kong has researched Phosphorylation in several fields, including Cancer research, ISG15, Acetylation, Gene and Promoter.
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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
Young-Yun Kong;Hiroki Yoshida;Ildiko Sarosi;Hong-Lin Tan.
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
Young-Yun Kong;Ulrich Feige;Iidiko Sarosi;Brad Bolon.
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
Nicholas Joza;Nicholas Joza;Santos A. Susin;Eric Daugas;William L. Stanford.
DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Atsushi Hirao;Young-Yun Kong;Shuhei Matsuoka;Andrew Wakeham.
Apaf1 is required for mitochondrial pathways of apoptosis and brain development.
Hiroki Yoshida;Hiroki Yoshida;Young-Yun Kong;Young-Yun Kong;Ritsuko Yoshida;Ritsuko Yoshida;Andrew J Elia;Andrew J Elia.
Regulation of cancer cell migration and bone metastasis by RANKL
D. Holstead Jones;Tomoki Nakashima;Otto H. Sanchez;Otto H. Sanchez;Ivona Kozieradzki;Ivona Kozieradzki.
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development.
Jimmie E Fata;Jimmie E Fata;Young-Yun Kong;Young-Yun Kong;Ji Li;Takehiko Sasaki.
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
Kurt Wolfgang Bachmaier;Connie Krawczyk;Ivona Kozieradzki;Young Yun Kong.
Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection
Yen-Tung A. Teng;Hai Nguyen;Xuijuan Gao;Young-Yun Kong.
Journal of Clinical Investigation (2000)
Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor.
K.-D. Fischer;Y.-Y. Kong;H. Nishina;K. Tedford.
Current Biology (1998)
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