Nobuyuki Udagawa

Overview

Best Publications

• Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

  Hisataka Yasuda;Nobuyuki Shima;Nobuaki Nakagawa;Kyoji Yamaguchi

  5728
  Citations

• Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.

  T. Suda;N. Takahashi;N. Udagawa;E. Jimi

  2908
  Citations

• IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

  Shigeru Kotake;Nobuyuki Udagawa;Naoyuki Takahashi;Kenichiro Matsuzaki

  2111
  Citations

• Tumor Necrosis Factor α Stimulates Osteoclast Differentiation by a Mechanism Independent of the Odf/Rankl–Rank Interaction

  Kanichiro Kobayashi;Naoyuki Takahashi;Eijiro Jimi;Nobuyuki Udagawa

  1590
  Citations

• Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

  N Udagawa;N Takahashi;T Akatsu;H Tanaka

  1391
  Citations

• Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

  T Tamura;N Udagawa;N Takahashi;C Miyaura

  1247
  Citations

• OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION

  N Takahashi;T Akatsu;N Udagawa;T Sasaki

  1194
  Citations

• A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function.

  Naoyuki Takahashi;Nobuyuki Udagawa;Tatsuo Suda

  696
  Citations

• Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors.

  S Tanaka;N Takahashi;N Udagawa;T Tamura

  680
  Citations

• Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

  Shigeru Kotake;Kazuto Sato;Kang Jung Kim;Naoyuki Takahashi

  679
  Citations

• Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients.

  Shigeru Kotake;Nobuyuki Udagawa;Masayuki Hakoda;Makio Mogi

  606
  Citations

• Osteoclast Differentiation Factor Acts as a Multifunctional Regulator in Murine Osteoclast Differentiation and Function

  Eijiro Jimi;Shuichi Akiyama;Taro Tsurukai;Nobuo Okahashi

  586
  Citations

• The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells.

  Nobuyuki Udagawa;Naoyuki Takahashi;Takuhiko Akatsu;Takahisa Sasaki

  566
  Citations

• Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation.

  N Udagawa;N J Horwood;J Elliott;A Mackay

  549
  Citations

• Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

  Kazuhiro Maeda;Yasuhiro Kobayashi;Nobuyuki Udagawa;Shunsuke Uehara

  538
  Citations

• Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function.

  Nobuyuki Udagawa;Naoyuki Takahashi;Hisataka Yasuda;Atsuko Mizuno

  533
  Citations

• Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor

  N. Udagawa;N. Takahashi;Eijiro Jimi;K. Matsuzaki

  515
  Citations

• Modulation of osteoclast differentiation by local factors

  T. Suda;N. Udagawa;I. Nakamura;C. Miyaura

  495
  Citations

• Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.

  Kenichiro Matsuzaki;Nobuyuki Udagawa;Naoyuki Takahashi;Kyoji Yamaguchi

  481
  Citations

• Coupling of bone resorption and formation by RANKL reverse signalling

  Yuki Ikebuchi;Shigeki Aoki;Masashi Honma;Madoka Hayashi

  457
  Citations