World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
42992
World Ranking
1635
National Ranking
914

Medicine

D-Index
98
Citations
42981
World Ranking
8819
National Ranking
4544

Overview

Yongwon Choi is affiliated with the University of Pennsylvania in the United States and conducts research primarily in the fields of biochemistry, genetics, molecular biology, and medicine. Their work encompasses molecular biology, oncology, immunology, orthopedics, sports medicine, and cancer research, reflecting a diverse focus on biological and medical sciences.

The main topics of Yongwon Choi's research include:

  • Bone Metabolism and Diseases
  • Bone health and treatments
  • Wnt/β-catenin signaling in development and cancer
  • Bone and Joint Diseases
  • NF-κB Signaling Pathways
  • Cytokine Signaling Pathways and Interactions
  • Immune Cell Function and Interaction

Yongwon Choi has contributed to a number of recent scientific publications spanning from 2020 to 2024. Some of the notable papers include:

  • "Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss," 2020, Journal of Clinical Investigation
  • "RANKL biology," 2022, Bone
  • "Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts," 2021, Nature Communications
  • "Unraveling the intricacies of osteoclast differentiation and maturation: insight into novel therapeutic strategies for bone-destructive diseases," 2024, Experimental & Molecular Medicine
  • "Regulation of T cell-associated tissues and T cell activation by RANKL-RANK-OPG," 2021, Journal of Bone and Mineral Metabolism

Frequent coauthors in Yongwon Choi's research include Hyunsoo Kim, Noriko Takegahara, Matthew C. Walsh, Lutian Yao, and Ling Qin. These collaborations are evident across various publications and represent recurring partnerships in their scientific efforts.

Yongwon Choi's work is commonly published in journals such as Bone Research, International Journal of Molecular Sciences, The Journal of Immunology, Cells, and bioRxiv (Cold Spring Harbor Laboratory). This distribution highlights the regular engagement with journals focused on bone biology, molecular science, and immunology.

Best Publications

  • TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

    A. Phillip West;Igor E. Brodsky;Igor E. Brodsky;Christoph Rahner;Dong Kyun Woo

  • Enhancing CD8 T-cell memory by modulating fatty acid metabolism.

    Erika L. Pearce;Matthew C. Walsh;Pedro J. Cejas;Gretchen M. Harms

  • Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

    Yongwon Choi;Brian Kotzin;Lynne Herron;Jill Callahan

  • TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells*

    Brian R. Wong;Jaerang Rho;Joseph Arron;Elizabeth Robinson

  • An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

    Gérard Eberl;Gérard Eberl;Shana Marmon;Mary-Jean Sunshine;Paul D Rennert

  • TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

    Brian R. Wong;Régis Josien;Soo Young Lee;Birthe Sauter

  • Bone versus immune system

    Joseph R. Arron;Yongwon Choi

  • Vβ-specific stimulation of human T cells by staphylococcal toxins

    John Kappler;Brian Kotzin;Lynne Herron;Erwin W. Gelfand

  • TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis.

    Allison R. Pettit;Hong Ji;Dietrich von Stechow;Ralph Müller;Ralph Müller

  • TRANCE Is Necessary and Sufficient for Osteoblast-mediated Activation of Bone Resorption in Osteoclasts

    Karen Fuller;Brian Wong;Simon Fox;Yongwon Choi

  • Distinct molecular mechanism for initiating TRAF6 signalling.

    Hong Ye;Joseph R. Arron;Joseph R. Arron;Betty Lamothe;Maurizio Cirilli

  • OSTEOIMMUNOLOGY: Interplay Between the Immune System and Bone Metabolism

    Matthew C. Walsh;Nacksung Kim;Yuho Kadono;Jaerang Rho

  • TRANCE, a TNF Family Member, Activates Akt/PKB through a Signaling Complex Involving TRAF6 and c-Src

    Brian R Wong;Daniel Besser;Nacksung Kim;Joseph R Arron

  • Osteoimmunology: interactions of the bone and immune system.

    Joseph Lorenzo;Mark Horowitz;Yongwon Choi

  • Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond.

    Matthew C. Walsh;Yongwon Choi

  • Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression

    Roger N. Pearse;Emilia M. Sordillo;Shmuel Yaccoby;Brian R. Wong

  • Evidence for a Role of a Tumor Necrosis Factor-α (TNF-α)-converting Enzyme-like Protease in Shedding of TRANCE, a TNF Family Member Involved in Osteoclastogenesis and Dendritic Cell Survival

    Lawrence Lum;Brian R. Wong;Régis Josien;J. David Becherer

  • TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival

    Soo Young Lee;Amy Reichlin;Angela Santana;Angela Santana;Karen A Sokol

  • v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.

    Seoung Hoon Lee;Jaerang Rho;Jaerang Rho;Daewon Jeong;Daewon Jeong;Daewon Jeong;Jai Yoon Sul

  • Osteoimmunology: Interplay Between the Immune System and Bone

    Matthew C. Walsh;Nacksung Kim;Yuho Kadono;Jaerang Rho

Frequent Co-Authors

Nacksung Kim
Nacksung Kim Chonnam National University
Hyun-Soo Kim
Hyun-Soo Kim University of Pennsylvania
John W. Kappler
John W. Kappler National Jewish Health
Takashi Kobayashi
Takashi Kobayashi Oita University
Philippa Marrack
Philippa Marrack National Jewish Health
Laurence A. Turka
Laurence A. Turka Harvard University
Régis Josien
Régis Josien Grenoble Alpes University
Hiroshi Takayanagi
Hiroshi Takayanagi University of Tokyo
Charles D. Surh
Charles D. Surh Pohang University of Science and Technology

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