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Joseph R. Arron

Joseph R. Arron

D-Index & Metrics

Immunology

D-Index
56
Citations
19094
World Ranking
3668
National Ranking
1692

Overview

Joseph R. Arron is affiliated with Genentech in the United States and has contributed extensively to the field of Medicine, with a particular focus on Pulmonary and Respiratory Medicine, Physiology, Immunology, Molecular Biology, and Pathology and Forensic Medicine. Their body of work spans research in asthma, respiratory diseases, interstitial lung diseases including idiopathic pulmonary fibrosis, IL-33/ST2/ILC pathways, neonatal respiratory health, systemic sclerosis, and chronic obstructive pulmonary disease (COPD).

The scientist has published multiple papers in high-impact journals, with recent publications including:

  • Cross-tissue organization of the fibroblast lineage, 2021, Nature
  • Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs, 2020, American Journal of Respiratory and Critical Care Medicine
  • Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial, 2020, The Lancet Respiratory Medicine
  • TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis, 2021, Science Translational Medicine
  • Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis, 2020, Cell Reports Medicine

Their research covers major topics including:

  • Asthma and respiratory diseases
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • IL-33, ST2, and ILC Pathways
  • Respiratory and Cough-Related Research
  • Neonatal Respiratory Health Research
  • Systemic Sclerosis and Related Diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research

Frequent co-authors in their work are:

  • David F. Choy (17 co-authored papers)
  • Peter Bradding (14 co-authored papers)
  • Rekha Chaudhuri (9 co-authored papers)
  • Adel Mansur (9 co-authored papers)
  • Cécile Holweg (9 co-authored papers)

Joseph R. Arron's publications have appeared repeatedly in several prominent scientific venues, including:

  • Science Translational Medicine
  • Journal of Allergy and Clinical Immunology
  • Allergy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Respiratory and Critical Care Medicine

Best Publications

  • T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

    Prescott G. Woodruff;Barmak Modrek;David F. Choy;Guiquan Jia

  • Lebrikizumab Treatment in Adults with Asthma

    Jonathan Corren;Robert F. Lemanske;Nicola A. Hanania;Phillip E. Korenblat

  • TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells*

    Brian R. Wong;Jaerang Rho;Joseph Arron;Elizabeth Robinson

  • Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study.

    Nicola A. Hanania;Sally Wenzel;Karin Rosén;Hsin-Ju Hsieh

  • Cross-tissue organization of the fibroblast lineage.

    Matthew B. Buechler;Rachana N. Pradhan;Akshay T. Krishnamurty;Christian Cox

  • Distinct molecular mechanism for initiating TRAF6 signalling.

    Hong Ye;Joseph R. Arron;Joseph R. Arron;Betty Lamothe;Maurizio Cirilli

  • TRANCE, a TNF Family Member, Activates Akt/PKB through a Signaling Complex Involving TRAF6 and c-Src

    Brian R Wong;Daniel Besser;Nacksung Kim;Joseph R Arron

  • Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.

    Guiquan Jia;Richard W. Erickson;David F. Choy;Sofia Mosesova

  • Dendritic Cell Development and Survival Require Distinct NF-κB Subunits

    Fateh Ouaaz;Joseph Arron;Ye Zheng;Yongwon Choi

  • The airway microbiome in patients with severe asthma: Associations with disease features and severity

    Yvonne J. Huang;Snehal Nariya;Jeffrey M. Harris;Susan V. Lynch

  • TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma

    David F. Choy;Kevin M. Hart;Lee A. Borthwick;Aarti Shikotra

  • The role of periostin in tissue remodeling across health and disease.

    Simon J. Conway;Kenji Izuhara;Yasusei Kudo;Judith Litvin

  • TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

    Hao Wu;Joseph R. Arron

  • Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma

    Aarti Shikotra;David F. Choy;Chandra M. Ohri;Emma Doran

  • Airway Epithelial miRNA Expression Is Altered in Asthma

    Owen D. Solberg;Edwin Justin Ostrin;Michael I. Love;Jeffrey C. Peng

  • A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production

    Laura J Simpson;Sana Patel;Nirav R Bhakta;David F Choy

  • Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids

    Michael Noonan;Phillip Korenblat;Sofia Mosesova;Heleen Scheerens

  • Roles of Periostin in Respiratory Disorders

    Kenji Izuhara;Simon J. Conway;Bethany B. Moore;Hisako Matsumoto

  • Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways

    David F. Choy;Barmak Modrek;Alexander R. Abbas;Sarah Kummerfeld

  • Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling

    Joseph R. Arron;Yael Pewzner-Jung;Matthew C. Walsh;Takashi Kobayashi

Frequent Co-Authors

Prescott G. Woodruff
Prescott G. Woodruff University of California, San Francisco
John V. Fahy
John V. Fahy University of California, San Francisco
Peter Bradding
Peter Bradding University of Leicester
Liam G. Heaney
Liam G. Heaney Queen's University Belfast
Paul J. Wolters
Paul J. Wolters University of California, San Francisco
Zora Modrusan
Zora Modrusan Genentech
Yongwon Choi
Yongwon Choi University of Pennsylvania
Harold R. Collard
Harold R. Collard University of California, San Francisco
Ratko Djukanovic
Ratko Djukanovic University of Southampton
Christopher E. Brightling
Christopher E. Brightling University of Leicester

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