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Immunology

D-Index
84
Citations
29776
World Ranking
1349
National Ranking
113

Overview

Peter Bradding is affiliated with the University of Leicester in the United Kingdom, contributing extensively to the field of Medicine with a particular focus on Pulmonary and Respiratory Medicine.

Their research covers various interconnected subfields including Physiology, Immunology, Immunology and Allergy, and Pediatrics, Perinatology and Child Health. These areas support investigations into respiratory diseases and immune responses related to asthma and other pulmonary conditions.

The main topics of their work include:

  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research
  • Inhalation and Respiratory Drug Delivery
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • IL-33, ST2, and ILC Pathways
  • Mast cells and histamine
  • Pharmaceutical studies and practices

Peter Bradding has authored and co-authored numerous scientific papers in reputable journals. Selected recent publications include:

  • "Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial," 2020, The Lancet Respiratory Medicine
  • "ACE2, TMPRSS2, and furin gene expression in the airways of people with asthma-implications for COVID-19," 2020, Journal of Allergy and Clinical Immunology
  • "Exacerbation Profile and Risk Factors in a Type-2-Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes," 2022, American Journal of Respiratory and Critical Care Medicine
  • "Airway hyperresponsiveness in asthma: The role of the epithelium," 2024, Journal of Allergy and Clinical Immunology
  • "Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma," 2021, American Journal of Respiratory and Critical Care Medicine

Frequent co-authors in their research collaborations include Liam G. Heaney, Rekha Chaudhuri, Joseph R. Arron, Adel Mansur, and Ian Pavord. These collaborations have been significant in advancing studies around asthma and respiratory medicine.

The publication venues where Peter Bradding frequently publishes are:

  • The Journal of Allergy and Clinical Immunology In Practice
  • Allergy
  • American Journal of Respiratory and Critical Care Medicine
  • Journal of Allergy and Clinical Immunology
  • European Respiratory Journal

Best Publications

  • Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

    Pranabashis Haldar;Christopher E. Brightling;Beverley Hargadon;Sumit Gupta

  • Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial.

    Ruth H Green;Christopher E Brightling;Susan McKenna;Beverley Hargadon

  • Mast-Cell Infiltration of Airway Smooth Muscle in Asthma

    Christopher E. Brightling;Peter Bradding;Fiona A. Symon;Stephen T. Holgate

  • Evidence of a role of tumor necrosis factor alpha in refractory asthma.

    Mike A. Berry;Beverley Hargadon;Maria Shelley;Debbie Parker

  • Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines.

    P Bradding;J A Roberts;K M Britten;S Montefort

  • The role of the mast cell in the pathophysiology of asthma.

    Peter Bradding;Andrew F. Walls;Stephen T. Holgate

  • Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.

    Guiquan Jia;Richard W. Erickson;David F. Choy;Sofia Mosesova

  • Interleukin 4 is localized to and released by human mast cells

    P Bradding;I H Feather;P H Howarth;R Mueller

  • Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma

    Mike Berry;Angela Morgan;Dominick E Shaw;Deborah Parker

  • TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma

    David F. Choy;Kevin M. Hart;Lee A. Borthwick;Aarti Shikotra

  • Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease

    C E Brightling;S McKenna;B Hargadon;S Birring

  • Macrophage and Mast-Cell Invasion of Tumor Cell Islets Confers a Marked Survival Advantage in Non–Small-Cell Lung Cancer

    Tomas J. Welsh;Ruth H. Green;Donna Richardson;David A. Waller

  • Heterogeneity of human mast cells based on cytokine content.

    P Bradding;Y Okayama;P H Howarth;M K Church

  • Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma

    Aarti Shikotra;David F. Choy;Chandra M. Ohri;Emma Doran

  • The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle

    Christopher E. Brightling;Alaina J. Ammit;Davinder Kaur;Judith L. Black

  • Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival.

    C M Ohri;A Shikotra;R H Green;D A Waller

  • Leukotriene antagonists and synthesis inhibitors: New directions in asthma therapy

    Stephen T. Holgate;Peter Bradding;Anthony P. Sampson

  • Comparison of airway immunopathology of eosinophilic bronchitis and asthma

    C E Brightling;F A Symon;S S Birring;P Bradding

  • Increased sputum and bronchial biopsy IL-13 expression in severe asthma

    Shironjit K. Saha;Mike A. Berry;Deborah Parker;Salman Siddiqui

  • The relationship between clinical outcomes and medication adherence in difficult-to-control asthma

    Anna C Murphy;Amandine Proeschal;Christopher E Brightling;Andrew J Wardlaw

  • IgE Sensitization to Aspergillus fumigatus Is Associated with Reduced Lung Function in Asthma

    Abbie Fairs;Joshua Agbetile;Beverley Hargadon;Michelle Bourne

Frequent Co-Authors

Christopher E. Brightling
Christopher E. Brightling University of Leicester
Andrew J. Wardlaw
Andrew J. Wardlaw University of Leicester
Ian D. Pavord
Ian D. Pavord University of Oxford
Yassine Amrani
Yassine Amrani University of Leicester
Liam G. Heaney
Liam G. Heaney Queen's University Belfast
Peter H. Howarth
Peter H. Howarth University of Southampton
Carol Feghali-Bostwick
Carol Feghali-Bostwick Medical University of South Carolina
Heike Wulff
Heike Wulff University of California, Davis
Stephen T. Holgate
Stephen T. Holgate University of Southampton

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