D-Index & Metrics

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 43 Citations 6,649 90 World Ranking 13650 National Ranking 3651

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Organic chemistry
  • Amino acid

His main research concerns Stereochemistry, Cyclic peptide, Peptide, Bioavailability and Allylic rearrangement. His Stereochemistry research integrates issues from PDE10A, Mannich reaction, Chemical synthesis and Enzyme inhibitor. His biological study spans a wide range of topics, including Combinatorial chemistry and Thio-.

In his research, Structure–activity relationship is intimately related to Membrane permeability, which falls under the overarching field of Bioavailability. His Structure–activity relationship research is multidisciplinary, relying on both Molecular mass and Small molecule. As part of one scientific family, Spiros Liras deals mainly with the area of Allylic rearrangement, narrowing it down to issues related to the Intramolecular force, and often Enantiomer.

His most cited work include:

  • The Future of Peptide‐based Drugs (966 citations)
  • On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds (215 citations)
  • Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia (173 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Stereochemistry, Combinatorial chemistry, Organic chemistry, Peptide and Pharmacology. The study incorporates disciplines such as Allylic rearrangement, Cyclopropanation, Receptor, GABAA receptor and Opioid receptor in addition to Stereochemistry. His Combinatorial chemistry research is multidisciplinary, incorporating elements of Selectivity and Total synthesis.

His studies deal with areas such as Amino acid, Structure–activity relationship and Bioavailability as well as Peptide. His Bioavailability study incorporates themes from Drug and Membrane permeability. His work on Small molecule as part of general Biochemistry research is often related to Proprotein convertase, thus linking different fields of science.

He most often published in these fields:

  • Stereochemistry (39.55%)
  • Combinatorial chemistry (15.67%)
  • Organic chemistry (14.93%)

What were the highlights of his more recent work (between 2013-2021)?

  • Peptide (13.43%)
  • Biochemistry (11.94%)
  • Cyclic peptide (9.70%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Peptide, Biochemistry, Cyclic peptide, Stereochemistry and Combinatorial chemistry. He has researched Peptide in several fields, including Amino acid, Structure–activity relationship, Amine gas treating and Agonist. His work in the fields of Biochemistry, such as Small molecule, overlaps with other areas such as Proprotein convertase and PDE1.

His studies in Cyclic peptide integrate themes in fields like Molecular dynamics, Permeability, Amide, Nuclear magnetic resonance spectroscopy and Membrane permeability. His Amide study combines topics in areas such as Bioavailability and Hydrogen bond. His research in the fields of Circular dichroism overlaps with other disciplines such as N methylation.

Between 2013 and 2021, his most popular works were:

  • Comparative α‐Helicity of Cyclic Pentapeptides in Water (99 citations)
  • Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable (88 citations)
  • Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients (79 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Organic chemistry
  • Amino acid

Spiros Liras mostly deals with Cyclic peptide, Peptide, Combinatorial chemistry, Membrane permeability and Amide. His Cyclic peptide study frequently links to adjacent areas such as Stereochemistry. Peptide is a subfield of Biochemistry that Spiros Liras explores.

The Combinatorial chemistry study combines topics in areas such as Nuclear magnetic resonance spectroscopy, Drug discovery and Solid-Phase Synthesis Techniques, Peptide synthesis. The various areas that Spiros Liras examines in his Membrane permeability study include Synthetic membrane and Permeability. His study on Amide also encompasses disciplines like

  • Bioavailability, which have a strong connection to Organic chemistry,
  • Solvent and related Derivative.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

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