World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
45
Citations
8241
World Ranking
16357
National Ranking
4074

Spiros Liras publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Spiros Liras sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 114 publications — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Spiros Liras D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Spiros Liras sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 45 D-Index — 10th percentile

10% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Spiros Liras is affiliated with the University of California, San Francisco in the United States. Their work spans multiple fields of study including Medicine, Biochemistry, Genetics and Molecular Biology, as well as Materials Science. Within these broader disciplines, Liras has contributed to subfields such as Materials Chemistry, Genetics, Cell Biology, Hematology, and Epidemiology.

The primary topics of research addressed by Liras include Hemoglobinopathies and Related Disorders, Hemoglobin Structure and Function, Iron Metabolism and Disorders, Liver Disease Diagnosis and Treatment, Drug Transport and Resistance Mechanisms, Peroxisome Proliferator-Activated Receptors, and Crystallization and Solubility Studies.

Recent publications by Spiros Liras are:

  • PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease, 2020, Journal of Medicinal Chemistry
  • Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting, 2020, Journal of Medicinal Chemistry
  • CCDC 1002286: Experimental Crystal Structure Determination, 2023, The Cambridge Structural Database

Liras frequently publishes in venues such as the Journal of Medicinal Chemistry and The Cambridge Structural Database.

Collaborations form an important part of Liras's research output. Frequent coauthors include Shawn Cabral, Robert L. Dow, Benjamin A. Thuma, David J. Edmonds, and David A. Griffith, each having coauthored multiple works with Liras.

Best Publications

  • The Future of Peptide‐based Drugs

    David J. Craik;David P. Fairlie;Spiros Liras;David Price

  • On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

    Tina R White;Chad M Renzelman;Arthur C Rand;Taha Rezai;Taha Rezai

  • Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia

    Patrick R. Verhoest;Douglas S. Chapin;Michael Corman;Kari Fonseca

  • Enantioselective Intramolecular Cyclopropanations of Allylic and Homoallylic Diazoacetates and Diazoacetamides Using Chiral Dirhodium(II) Carboxamide Catalysts

    Michael P. Doyle;Richard E. Austin;A. Scott Bailey;Michael P. Dwyer

  • Comparative α‐Helicity of Cyclic Pentapeptides in Water

    Aline D. de Araujo;Huy N. Hoang;W. Mei Kok;Frederik Diness;Frederik Diness

  • Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients

    Conan K. Wang;Susan E. Northfield;Barbara Colless;Stephanie Chaousis

  • Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing.

    Romain Rouet;Benjamin A. Thuma;Marc D. Roy;Nathanael G. Lintner

  • Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus.

    Jeffrey A. Pfefferkorn;Angel Guzman-Perez;John Litchfield;Robert Aiello

  • Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.

    Cameron R. Pye;William M. Hewitt;Joshua Schwochert;Terra D. Haddad

  • A Mild Method for the Preparation of 1,3,4-Oxadiazoles: Triflic Anhydride Promoted Cyclization of Diacylhydrazines

    Spiros Liras;Martin P. Allen;Barb E. Segelstein

  • Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable

    Daniel S. Nielsen;Huy N. Hoang;Rink-Jan Lohman;Timothy A. Hill

  • Probing the Physicochemical Boundaries of Cell Permeability and Oral Bioavailability in Lipophilic Macrocycles Inspired by Natural Products

    Andrew T. Bockus;Katrina W. Lexa;Cameron R. Pye;Amit S. Kalgutkar

  • Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.

    Thomas A. Chappie;John M. Humphrey;Martin P. Allen;Kimberly G. Estep

  • Use of 3D properties to characterize beyond rule-of-5 property space for passive permeation.

    Cristiano R. W. Guimarães;Alan M. Mathiowetz;Marina Shalaeva;Gilles Goetz

  • Peptidic macrocyclization via palladium-catalyzed chemoselective indole C-2 arylation.

    Huijun Dong;Chris Limberakis;Spiros Liras;David Price

  • Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance

    Arthur C. Rand;Siegfried S. F. Leung;Heather Eng;Charles J. Rotter

  • Fmoc-based Synthesis of Disulfide-Rich Cyclic Peptides

    Olivier Cheneval;Christina I. Schroeder;Thomas Durek;Phillip Walsh

  • Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

    Nathanael G. Lintner;Kim F. McClure;Donna Petersen;Allyn T. Londregan

  • ENANTIO- AND DIASTEREOSELECTIVITY IN THE INTRAMOLECULAR CYCLOPROPANATION OF SECONDARY ALLYLIC DIAZOACETATES

    Stephen F. Martin;Mark R. Spaller;Spiros Liras;Benoit Hartmann

  • Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor

    Carlos A. Sanhueza;Carlos A. Sanhueza;Michael M. Baksh;Michael M. Baksh;Benjamin Thuma;Marc D. Roy

  • Applications of Vinylogous Mannich Reactions. Total Syntheses of the Ergot Alkaloids Rugulovasines A and B and Setoclavine

    Spiros Liras;Christopher L. Lynch;Andrew M. Fryer;Binh T. Vu

Frequent Co-Authors

David Price
David Price University of Aberdeen
Stephen F. Martin
Stephen F. Martin The University of Texas at Austin
David J. Craik
David J. Craik University of Queensland
David P. Fairlie
David P. Fairlie University of Queensland
Amit S. Kalgutkar
Amit S. Kalgutkar Pfizer (United States)
Jamie H. D. Cate
Jamie H. D. Cate University of California, Berkeley
Matthew P. Jacobson
Matthew P. Jacobson University of California, San Francisco
Jeffrey A. Pfefferkorn
Jeffrey A. Pfefferkorn Pfizer (United States)
Michael P. Doyle
Michael P. Doyle The University of Texas at San Antonio
Jennifer A. Doudna
Jennifer A. Doudna University of California, Berkeley

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