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Zora Modrusan

Zora Modrusan

D-Index & Metrics

Biology and Biochemistry

D-Index
105
Citations
48186
World Ranking
1182
National Ranking
703

Overview

Zora Modrusan is affiliated with Genentech in the United States and has a significant research output in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work encompasses multiple subfields including Molecular Biology, Immunology, Oncology, Pulmonary and Respiratory Medicine, and Cell Biology.

Their research covers a range of topics such as Single-cell and spatial transcriptomics, Immune cells in cancer, Cancer Immunotherapy and Biomarkers, Cancer Genomics and Diagnostics, Immune Cell Function and Interaction, CAR-T cell therapy research, and Endoplasmic Reticulum Stress and Disease.

Recent notable papers authored or coauthored by Modrusan include:

  • Cross-tissue organization of the fibroblast lineage (2021) published in Nature
  • Peripheral T cell expansion predicts tumour infiltration and clinical response (2020) published in Nature
  • NINJ1 mediates plasma membrane rupture during lytic cell death (2021) published in Nature
  • High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade (2020) published in Nature Medicine
  • Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation (2020) published in Cell Reports

The scientist frequently collaborates with a network of coauthors including Ira Mellman, Yeqing Angela Yang, Merone Roose-Girma, Scott E. Martin, and Thomas D. Wu. These collaborations have resulted in multiple joint publications.

Zora Modrusan's research has been published in various scientific venues, with a high frequency of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Reports
  • Nature
  • Cell Reports Medicine

Best Publications

  • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

    Heidi S. Phillips;Samir Kharbanda;Ruihuan Chen;William F. Forrest

  • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

    Yan Zheng;Patricia A Valdez;Dimitry M Danilenko;Yan Hu

  • Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

    Mahesh Yadav;Suchit Jhunjhunwala;Qui T. Phung;Patrick Lupardus

  • Diverse somatic mutation patterns and pathway alterations in human cancers

    Zhengyan Kan;Bijay S. Jaiswal;Jeremy Stinson;Vasantharajan Janakiraman

  • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

    Charles M Rudin;Steffen Durinck;Eric W Stawiski;John T Poirier

  • Recurrent R-spondin fusions in colon cancer

    Somasekar Seshagiri;Eric W. Stawiski;Steffen Durinck;Zora Modrusan

  • Cross-tissue organization of the fibroblast lineage.

    Matthew B. Buechler;Rachana N. Pradhan;Akshay T. Krishnamurty;Christian Cox

  • Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

    Raphael Bueno;Eric W Stawiski;Leonard D Goldstein;Steffen Durinck

  • Peripheral T cell expansion predicts tumour infiltration and clinical response

    Thomas D. Wu;Shravan Madireddi;Patricia E. de Almeida;Romain Banchereau

  • Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

    Marcin Kowanetz;Xiumin Wu;John Lee;Martha Tan

  • A hierarchy of self-renewing tumor-initiating cell types in glioblastoma

    Ruihuan Chen;Merry C. Nishimura;Stephanie M. Bumbaca;Samir Kharbanda

  • A comprehensive transcriptional portrait of human cancer cell lines

    Christiaan Klijn;Steffen Durinck;Eric W Stawiski;Peter M Haverty

  • PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment.

    Yongping Crawford;Ian Kasman;Lanlan Yu;Cuiling Zhong

  • Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients.

    Robert L. Yauch;Thomas Januario;David A. Eberhard;Guy Cavet

  • The mutation spectrum revealed by paired genome sequences from a lung cancer patient

    William Lee;Zhaoshi Jiang;Jinfeng Liu;Peter M. Haverty

  • The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

    Susan M. Sa;Patricia A. Valdez;Jianfeng Wu;Kenneth Jung

  • A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

    Felipe de Sousa e Melo;Antonina V. Kurtova;Jonathan M. Harnoss;Noelyn Kljavin

  • Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

    H S Günther;N O Schmidt;H S Phillips;D Kemming

  • Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

    Claudia X. Dominguez;Sören Müller;Shilpa Keerthivasan;Hartmut Koeppen

  • Abstract LB-331: Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

    Somasekar Seshagiri;Eric Stawiski;Leonard Goldstein;Steffen Durinck

Frequent Co-Authors

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