World's Best Scientists 2026 revealed!
Vishva M. Dixit

Vishva M. Dixit

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Best Scientists
2025
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Best Scientists

D-Index
168
Citations
143690
World Ranking
929
National Ranking
551

Biology and Biochemistry

D-Index
172
Citations
150054
World Ranking
80
National Ranking
62

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2013 - Member of the National Academy of Sciences
  • 2012 - Member of the National Academy of Medicine (NAM)
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Vishva M. Dixit is affiliated with Genentech in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research spans several subfields including molecular biology, immunology, epidemiology, cell biology, and pulmonary and respiratory medicine.

The main topics of their work include inflammasome and immune disorders, cell death mechanisms and regulation, immune response and inflammation, ubiquitin and proteasome pathways, interferon and immune responses, autophagy in disease and therapy, and heme oxygenase-1 and carbon monoxide.

Dixit has published in numerous scientific venues, with the most frequent being:

  • Nature
  • Cell
  • Cell Death and Differentiation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science

Recent papers authored by or involving Dixit include:

  • "NINJ1 mediates plasma membrane rupture during lytic cell death" (2021, Nature)
  • "Cell death" (2024, Cell)
  • "Dying cells fan the flames of inflammation" (2021, Science)
  • "Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection" (2021, Cell Host & Microbe)
  • "Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia" (2020, Cell)

Frequent co-authors collaborating with Dixit include:

  • Kim Newton
  • Joshua D. Webster
  • Nobuhiko Kayagaki
  • Rohit Reja
  • Christopher M. Rose

The scientist has received several honors recognizing their contributions to science, including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2020
  • Member of the National Academy of Sciences, 2013
  • Member of the National Academy of Medicine (NAM), 2012
  • Fellow of the American Academy of Arts and Sciences, 2011
  • Member of the Association of American Physicians

Best Publications

  • Death receptors: signaling and modulation

    Avi Ashkenazi;Vishva M. Dixit

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

    Marta Muzio;Arul M. Chinnaiyan;Frank C. Kischkel;Karen O'Rourke

  • Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

    Nobuhiko Kayagaki;Irma B. Stowe;Bettina L. Lee;Karen O’Rourke

  • Cryopyrin activates the inflammasome in response to toxins and ATP

    Sanjeev Mariathasan;David S. Weiss;Kim Newton;Jacqueline McBride

  • FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

    Arul M. Chinnaiyan;Karen O'Rourke;Muneesh Tewari;Vishva M. Dixit

  • Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway REQUIREMENT FOR Flk-1/KDR ACTIVATION

    Hans Peter Gerber;Amy McMurtrey;Joe Kowalski;Minhong Yan

  • Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

    Muneesh Tewari;Long T Quan;Karen O'Rourke;Serge Desnoyers

  • Inflammasomes: mechanism of assembly, regulation and signalling

    Petr Broz;Vishva M. Dixit

  • CASPASES : INTRACELLULAR SIGNALING BY PROTEOLYSIS

    Guy S Salvesen;Vishva M Dixit

  • Non-canonical inflammasome activation targets caspase-11

    Nobuhiko Kayagaki;Søren Warming;Mohamed Lamkanfi;Lieselotte Vande Walle

  • Mechanisms and Functions of Inflammasomes

    Mohamed Lamkanfi;Vishva M. Dixit

  • The receptor for the cytotoxic ligand TRAIL

    Guohua Pan;Karen O'Rourke;Arul M. Chinnaiyan;Reiner Gentz

  • De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

    Ingrid E. Wertz;Karen M. O'Rourke;Honglin Zhou;Michael Eby

  • Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.

    Sanjeev Mariathasan;Kim Newton;Denise M. Monack;Domagoj Vucic

  • An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

    Guohua Pan;Jian Ni;Jian Ni;Ying Fei Wei;Ying Fei Wei;Guo Liang Yu;Guo Liang Yu

  • Signaling in Innate Immunity and Inflammation

    Kim Newton;Vishva M. Dixit

  • Apoptosis control by death and decoy receptors

    Avi Ashkenazi;Vishva M Dixit

  • Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

    Nobuhiko Kayagaki;Michael T. Wong;Irma B. Stowe;Sree Ranjani Ramani

  • An Induced Proximity Model for Caspase-8 Activation

    Marta Muzio;Brent R. Stockwell;Henning R. Stennicke;Guy S. Salvesen

Frequent Co-Authors

Kim Newton
Kim Newton Genentech
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Wyne P. Lee
Wyne P. Lee Genentech
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
James Varani
James Varani University of Michigan–Ann Arbor
Mohamed Lamkanfi
Mohamed Lamkanfi Ghent University

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