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Biology and Biochemistry

D-Index
67
Citations
13883
World Ranking
8327
National Ranking
3759

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert I. Handin is affiliated with Brigham and Women's Hospital in the United States. Their research spans several fields, centering primarily on Medicine and extending into Biochemistry, Genetics and Molecular Biology. The scientist's work includes subfields such as Hematology, Genetics, Physiology, Cell Biology, and Molecular Biology.

They have contributed notably to topics including Hemophilia Treatment and Research, Platelet Disorders and Treatments, Coagulation, Bradykinin, Polyphosphates, and Angioedema, as well as Erythrocyte Function and Pathophysiology, Cellular Transport and Secretion, Ion Channel Regulation and Function, and Chronic Myeloid Leukemia Treatments.

Some recent papers authored or co-authored by Robert I. Handin are:

  • Emicizumab for the treatment of acquired hemophilia A: Retrospective review of a single-institution experience, 2022, Haemophilia
  • Dysregulated myosin in Hermansky-Pudlak syndrome lung fibroblasts is associated with increased cell motility, 2022, Respiratory Research
  • Treatment of Acquired Hemophilia a with Rituximab and Emicizumab, 2020, Blood

Their frequent co-authors include Evan C. Chen, William J. Gibson, Paula Temoczko, Nathan T. Connell, and Aric Parnes, each with multiple collaborations.

Robert I. Handin's publications often appear in journals such as Haemophilia, Respiratory Research, and Blood. These venues align with their research focus on hematologic disorders and related physiological processes.

Among the professional recognitions, Robert I. Handin is a member of the Association of American Physicians.

Best Publications

  • Tracing Hematopoietic Precursor Migration to Successive Hematopoietic Organs during Zebrafish Development

    Emi Murayama;Karima Kissa;Agustin Zapata;Elodie Mordelet

  • Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization

    David Ginsburg;David Ginsburg;Robert I. Handin;Robert I. Handin;David T. Bonthron;Timothy A. Donlon;Timothy A. Donlon

  • Analysis of thrombocyte development in CD41-GFP transgenic zebrafish.

    Hui Feng Lin;David Traver;David Traver;Hao Zhu;Kimberly Dooley;Kimberly Dooley

  • von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

    Michael H. Kroll;Terese S. Harris;Joel L. Moake;Robert I. Handin

  • Blood: Principles and Practice of Hematology

    Robert I. Handin;Samuel E. Lux;Thomas P. Stossel

  • Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib.

    Jonas Emsley;Miguel Cruz;Robert Handin;Robert Liddington

  • Purification and binding properties of human platelet factor four.

    Robert I. Handin;Howard J. Cohen

  • Characterization of a new megakaryocytic cell line: the Dami cell.

    Sheryl M. Greenberg;David S. Rosenthal;Tammy A. Greeley;Ramana Tantravahi

  • Identification of adult nephron progenitors capable of kidney regeneration in zebrafish

    Cuong Q. Diep;Dongdong Ma;Rahul C. Deo;Teresa M. Holm

  • Structure of pre-pro-von Willebrand factor and its expression in heterologous cells

    David T. Bonthron;David T. Bonthron;David T. Bonthron;Robert I. Handin;Randal J. Kaufman;Louise C. Wasley

  • Enhancement of platelet function by superoxide anion.

    Robert I. Handin;Richard Karabin;Grace J. Boxer

  • Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions

    Burt Adelman;Alan D. Michelson;Joseph Loscalzo;Joshua Greenberg

  • Circulating platelet products in unstable angina pectoris.

    M Sobel;E W Salzman;G C Davies;R I Handin

  • The propeptide of von Willebrand Factor independently mediates the assembly of von Willebrand multimers

    Robert J. Wise;Robert J. Wise;Debra D. Pittman;Robert I. Handin;Randal J. Kaufman

  • Composition of the von Willebrand factor storage organelle (Weibel-Palade body) isolated from cultured human umbilical vein endothelial cells.

    B M Ewenstein;M J Warhol;R I Handin;J S Pober

  • Inhibition of platelet function by organic nitrate vasodilators.

    AI Schafer;RW Alexander;RI Handin

  • Interaction of the von Willebrand Factor (vWF) with Collagen LOCALIZATION OF THE PRIMARY COLLAGEN-BINDING SITE BY ANALYSIS OF RECOMBINANT vWF A DOMAIN POLYPEPTIDES

    Miguel A. Cruz;Huabing Yuan;Joseph R. Lee;Robert J. Wise

  • Identification of platelet receptors for prostaglandin I2 and D2.

    A I Schafer;B Cooper;D O'Hara;R I Handin

  • Platelet membrane glycoprotein IIIa contains target antigens that bind anti-platelet antibodies in immune thrombocytopenias.

    D S Beardsley;J E Spiegel;M M Jacobs;R I Handin

  • Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Commentary

    Pudur Jagadeeswaran;Hui-Feng Lin;David Traver;Hao Zhu

Frequent Co-Authors

Andrew I. Schafer
Andrew I. Schafer Cornell University
Joseph Loscalzo
Joseph Loscalzo Harvard Medical School
Alan D. Michelson
Alan D. Michelson Harvard University
Leonard I. Zon
Leonard I. Zon Harvard University
Michael A. Gimbrone
Michael A. Gimbrone Brigham and Women's Hospital
Stuart H. Orkin
Stuart H. Orkin Harvard University
Nikhil C. Munshi
Nikhil C. Munshi Harvard University
Barry H. Paw
Barry H. Paw Brigham and Women's Hospital
David T. Bonthron
David T. Bonthron University of Leeds
David Traver
David Traver University of California, San Diego

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