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Philippe Herbomel

Philippe Herbomel

Institut Pasteur
France

Overview

What is he best known for?

The fields of study he is best known for:

Gene
DNA
Genetics

Philippe Herbomel mostly deals with Zebrafish, Cell biology, Gene, Genetics and Haematopoiesis. He performs multidisciplinary study in Zebrafish and Model system in his work. His study in the fields of Mesenchyme and Progenitor cell under the domain of Cell biology overlaps with other disciplines such as Context.

In his research, Common gamma chain is intimately related to Receptor, which falls under the overarching field of Gene. His research in the fields of Subfamily, Protein family and Phylogenetic tree overlaps with other disciplines such as Exon shuffling. His biological study deals with issues like Cellular differentiation, which deal with fields such as In situ hybridization, Blood islands and Mesoderm.

His most cited work include:

Blood stem cells emerge from aortic endothelium by a novel type of cell transition (658 citations)
Ontogeny and behaviour of early macrophages in the zebrafish embryo (606 citations)
Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma (578 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Zebrafish, Cell biology, Haematopoiesis, Stem cell and Immunology. His Zebrafish study integrates concerns from other disciplines, such as Innate immune system, Cell type, In vivo and Microbiology. In general Cell biology study, his work on Progenitor cell and Mesenchyme often relates to the realm of Population, thereby connecting several areas of interest.

The Haematopoiesis study combines topics in areas such as Blood vessel, Blood flow and Cellular differentiation. His studies deal with areas such as Cancer research, Live cell imaging, Blood cell, White blood cell and Developmental biology as well as Stem cell. Philippe Herbomel combines subjects such as Regulation of gene expression, Stromal cell, Transcriptional regulation and Virology with his study of Immunology.

He most often published in these fields:

Zebrafish (128.57%)
Cell biology (86.81%)
Haematopoiesis (35.16%)

What were the highlights of his more recent work (between 2017-2021)?

Cell biology (86.81%)
Zebrafish (128.57%)
Haematopoiesis (35.16%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Zebrafish, Haematopoiesis, Stem cell and Population. Philippe Herbomel has included themes like Antigen, Lineage, Cell type and In vivo in his Cell biology study. His Zebrafish study combines topics from a wide range of disciplines, such as Innate immune system and Superinfection.

His Innate immune system research incorporates elements of Bacteria, Virus, Interleukin 10 and Microbiology. The study incorporates disciplines such as Progenitor cell and PI3K/AKT/mTOR pathway, PTEN in addition to Haematopoiesis. His research in Stem cell intersects with topics in Blood vessel, Blood flow, Blood cell, White blood cell and Developmental biology.

Between 2017 and 2021, his most popular works were:

Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo. (92 citations)
A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death. (11 citations)
A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death. (11 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

Philippe Herbomel;Brigitte Bourachot;Moshe Yaniv.
Cell (1984)

1077 Citations

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

Karima Kissa;Philippe Herbomel.
Nature (2010)

1035 Citations

Ontogeny and behaviour of early macrophages in the zebrafish embryo

Philippe Herbomel;Bernard Thisse;Christine Thisse.
Development (1999)

997 Citations

Zebrafish Early Macrophages Colonize Cephalic Mesenchyme and Developing Brain, Retina, and Epidermis through a M-CSF Receptor-Dependent Invasive Process

Philippe Herbomel;Bernard Thisse;Christine Thisse.
Developmental Biology (2001)

656 Citations

Real-time visualization of Mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos

J.Muse Davis;Hilary Clay;Jessica L. Lewis;Nafisa Ghori.
Immunity (2002)

628 Citations

Tracing Hematopoietic Precursor Migration to Successive Hematopoietic Organs during Zebrafish Development

Emi Murayama;Karima Kissa;Agustin Zapata;Elodie Mordelet.
Immunity (2006)

512 Citations

Factors involved in control of tissue-specific expression of albumin gene

Silvia Cereghini;Michel Raymondjean;Alejandro Garcia Carranca;Philippe Herbomel.
Cell (1987)

434 Citations

Origins and unconventional behavior of neutrophils in developing zebrafish

Dorothée Le Guyader;Michael J. Redd;Emma Colucci-Guyon;Emi Murayama.
Blood (2008)

359 Citations

The zebrafish as a model organism to study development of the immune system.

David Traver;Philippe Herbomel;E Elizabeth Patton;Ryan D Murphey.
Advances in Immunology (2003)

299 Citations

Identification of the Zebrafish IFN Receptor: Implications for the Origin of the Vertebrate IFN System

Jean-Pierre Levraud;Pierre Boudinot;Ingrid Colin;Abdenour Benmansour.
Journal of Immunology (2007)

260 Citations

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Frequent Co-Authors

External Links

Personal Website for Philippe Herbomel