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Philippe Herbomel

Philippe Herbomel

D-Index & Metrics

Biology and Biochemistry

D-Index
40
Citations
11382
World Ranking
19575
National Ranking
952

Overview

Philippe Herbomel is affiliated with the Institut Pasteur in France and specializes in fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Their research career encompasses extensive work in cell biology, immunology, molecular biology, physiology, and hematology.

Their scientific output includes a focus on zebrafish biomedical research applications, immune cells in cancer, hematopoietic stem cell transplantation, epigenetics and DNA methylation, erythrocyte function and pathophysiology, ATP synthase and ATPases research, and adenosine and purinergic signaling.

Herbomel's recent research publications include:

  • The different roles of V-ATPase a subunits in phagocytosis/endocytosis and autophagy, 2024, Autophagy
  • Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis, 2023, Nature Communications
  • The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity, 2020, Journal of Cell Science
  • Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells, 2021, Oncogene
  • A dual involvement of Protocadherin 18a in stromal cell development guides the formation of a functional hematopoietic niche, 2022, Development

Frequent collaborators include Doris Lou Demy, Anne-Lou Touret, Emi Murayama, Catherine Vivier, and Anne Schmidt.

Herbomel has published notably in venues such as bioRxiv (Cold Spring Harbor Laboratory), Development, Autophagy, Nature Communications, and Journal of Cell Science, with the highest number of publications appearing in bioRxiv. These outlets reflect the interdisciplinary nature and biomedical emphasis of their work.

Their research integrates molecular and cellular approaches to investigate immune cell function, hematopoiesis, and the molecular mechanisms underpinning cellular processes in model organisms like zebrafish. This approach positions their work at the intersection of cell biology, immunology, and hematology with applications to understanding disease mechanisms and stem cell biology.

Best Publications

  • Blood stem cells emerge from aortic endothelium by a novel type of cell transition

    Karima Kissa;Philippe Herbomel

  • Ontogeny and behaviour of early macrophages in the zebrafish embryo

    Philippe Herbomel;Bernard Thisse;Christine Thisse

  • Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

    Philippe Herbomel;Brigitte Bourachot;Moshe Yaniv

  • Zebrafish Early Macrophages Colonize Cephalic Mesenchyme and Developing Brain, Retina, and Epidermis through a M-CSF Receptor-Dependent Invasive Process

    Philippe Herbomel;Bernard Thisse;Christine Thisse

  • Real-time visualization of Mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos

    J.Muse Davis;Hilary Clay;Jessica L. Lewis;Nafisa Ghori

  • Tracing Hematopoietic Precursor Migration to Successive Hematopoietic Organs during Zebrafish Development

    Emi Murayama;Karima Kissa;Agustin Zapata;Elodie Mordelet

  • Origins and unconventional behavior of neutrophils in developing zebrafish

    Dorothée Le Guyader;Michael J. Redd;Emma Colucci-Guyon;Emi Murayama

  • Factors involved in control of tissue-specific expression of albumin gene

    Silvia Cereghini;Michel Raymondjean;Alejandro Garcia Carranca;Philippe Herbomel

  • The zebrafish as a model organism to study development of the immune system.

    David Traver;Philippe Herbomel;E Elizabeth Patton;Ryan D Murphey

  • The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains.

    Dina Aggad;Martine Mazel;Pierre Boudinot;Knud Erik Mogensen

  • Identification of the Zebrafish IFN Receptor: Implications for the Origin of the Vertebrate IFN System

    Jean-Pierre Levraud;Pierre Boudinot;Ingrid Colin;Abdenour Benmansour

  • Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo.

    Frederik J. Verweij;Frederik J. Verweij;Celine Revenu;Guillaume Arras;Florent Dingli

  • Live imaging of emerging hematopoietic stem cells and early thymus colonization.

    Karima Kissa;Emi Murayama;Agustin Zapata;Alfonso Cortés

  • Tissue-specific expression is conferred by a sequence from the 5' end of the rat albumin gene.

    M.O. Ott;L. Sperling;P. Herbomel;M. Yaniv

  • The Zebrafish as a New Model for the In Vivo Study of Shigella flexneri Interaction with Phagocytes and Bacterial Autophagy

    Serge Mostowy;Laurent Boucontet;Laurent Boucontet;Maria J. Mazon Moya;Andrea Sirianni

  • Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish.

    Nuno R Palha;Florence Guivel-Benhassine;Florence Guivel-Benhassine;Valérie Briolat;Valérie Briolat;Georges Lutfalla;Georges Lutfalla

  • A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish

    Lieke M van der Aa;Lieke M van der Aa;Jean-Pierre Levraud;Malika Yahmi;Emilie Lauret

  • Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients.

    Milka Sarris;Milka Sarris;Jean-Baptiste Masson;Jean-Baptiste Masson;Damien Maurin;Lieke M. Van der Aa;Lieke M. Van der Aa

  • Otolith matrix proteins OMP-1 and Otolin-1 are necessary for normal otolith growth and their correct anchoring onto the sensory maculae.

    Emi Murayama;Philippe Herbomel;Atsushi Kawakami;Hiroyuki Takeda

  • Origins and unconventional behavior of neutrophils in developing zebrafish. Commentary

    Mitchell S. Cairo;Dorothée Le Guyader;Michael J. Redd;Emma Colucci-Guyon

Frequent Co-Authors

Jean-Pierre Levraud
Jean-Pierre Levraud Institut Pasteur
Pierre Boudinot
Pierre Boudinot Versailles Saint-Quentin-en-Yvelines University
Agustín G. Zapata
Agustín G. Zapata Complutense University of Madrid
Georges Lutfalla
Georges Lutfalla University of Montpellier
Moshe Yaniv
Moshe Yaniv Institut Pasteur
Pascale Cossart
Pascale Cossart Institut Pasteur
Jeroen den Hertog
Jeroen den Hertog Hubrecht Institute for Developmental Biology and Stem Cell Research
Olivier Schwartz
Olivier Schwartz Université Paris Cité
Marc Lecuit
Marc Lecuit Institut Pasteur
Graça Raposo
Graça Raposo Institut Curie

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