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D-Index & Metrics

Molecular Biology

D-Index
64
Citations
13675
World Ranking
1752
National Ranking
139

Overview

Roger Patient is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions in molecular biology, cancer research, cell biology, cardiology and cardiovascular medicine, and immunology.

The scientist's work covers several significant research topics, including congenital heart defects research, zebrafish biomedical research applications, cancer-related molecular mechanisms research, epigenetics and DNA methylation, microRNA in disease regulation, cardiac fibrosis and remodeling, and immune cell function and interaction.

Roger Patient has published research in various peer-reviewed journals. Some notable papers include:

  • Functional Heterogeneity within the Developing Zebrafish Epicardium, 2020, Developmental Cell
  • Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration, 2020, Development
  • Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis, 2020, Communications Biology
  • LSD1 promotes the egress of hematopoietic stem and progenitor cells into the bloodstream during the endothelial-to-hematopoietic transition, 2023, Developmental Biology
  • Three-Dimensional Visualization of Blood and Lymphatic Vessels in the Adult Zebrafish Heart by Chemical Clearing, 2022, Methods in molecular biology

The frequent coauthors collaborating with Roger Patient include Paul R. Riley, Florian Bonkhofer, Michael Weinberger, Filipa C. Simões, and Tatjana Sauka-Spengler.

Roger Patient's publications often appear in journals such as Developmental Cell, Development, Communications Biology, Developmental Biology, and Methods in molecular biology. Their research engages deeply with zebrafish models, particularly in contexts of cardiovascular development and regeneration, hematopoiesis, and epigenetic regulation.

Best Publications

  • The GATA family (vertebrates and invertebrates).

    Roger K Patient;James D McGhee

  • The transcription factor GATA6 is essential for early extraembryonic development.

    Manoussos Koutsourakis;An Langeveld;Roger Patient;Rosa Beddington

  • Gata5 is required for the development of the heart and endoderm in zebrafish

    Jeremy F. Reiter;Jonathan Alexander;Adam Rodaway;Deborah Yelon

  • The SCL gene specifies haemangioblast development from early mesoderm

    M. Gering;A.R.F. Rodaway;B. Göttgens;R.K. Patient

  • Hedgehog Signaling Is Required for Adult Blood Stem Cell Formation in Zebrafish Embryos

    Martin Gering;Roger Patient

  • Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos.

    Louise A Brown;Adam R.F Rodaway;Thomas F Schilling;Trevor Jowett

  • A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

    Massimo Masiero;Filipa Costa Simões;Hee Dong Han;Cameron Snell

  • Distinct origins of adult and embryonic blood in Xenopus.

    Aldo Ciau-Uitz;Maggie Walmsley;Roger Patient

  • Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.

    Berthold Göttgens;Aristotelis Nastos;Sarah Kinston;Sandie Piltz

  • The roles of GATA-4, -5 and -6 in vertebrate heart development.

    Tessa Peterkin;Abigail Gibson;Matthew Loose;Roger Patient

  • Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification.

    Gemma Swiers;Roger Patient;Matthew Loose

  • Mesendoderm. an ancient germ layer

    Adam Rodaway;Roger Patient

  • Scl is required for dorsal aorta as well as blood formation in zebrafish embryos.

    Lucy J. Patterson;Martin Gering;Roger Patient

  • Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene.

    David R. Greaves;Roger K. Patient;David M.J. Lilley

  • Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.

    Hannah K Long;David Sims;Andreas Heger;Neil P Blackledge

  • Fli1 acts at the top of the transcriptional network driving blood and endothelial development.

    Feng Liu;Maggie Walmsley;Adam Rodaway;Roger Patient

  • The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish

    Lucy J. Patterson;Martin Gering;Craig E. Eckfeldt;Anthony R. Green

  • The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis.

    Gemma Bridge;Rui Monteiro;Stephen Henderson;Victoria Emuss

  • A genetic regulatory network for Xenopus mesendoderm formation.

    Matthew Loose;Roger Patient

  • Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1.

    Martin Gering;Yoshihiro Yamada;Terence H. Rabbitts;Roger K. Patient

Frequent Co-Authors

Tariq Enver
Tariq Enver University College London
Berthold Göttgens
Berthold Göttgens University of Cambridge
Paresh Vyas
Paresh Vyas University of Oxford
Sten Eirik W. Jacobsen
Sten Eirik W. Jacobsen University of Oxford
Claus Nerlov
Claus Nerlov University of Oxford
Paul R. Riley
Paul R. Riley University of Oxford
Anthony R. Green
Anthony R. Green University of Cambridge
Tatjana Sauka-Spengler
Tatjana Sauka-Spengler University of Oxford
Rickard Sandberg
Rickard Sandberg Karolinska Institute
Duncan T. Odom
Duncan T. Odom University of Cambridge

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