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Tatjana Sauka-Spengler

Tatjana Sauka-Spengler

D-Index & Metrics

Genetics

D-Index
48
Citations
11491
World Ranking
4042
National Ranking
461

Overview

Tatjana Sauka-Spengler is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a strong emphasis on developmental biology and gene regulation, genomics, and cancer research.

The most frequent topics of their work include:

  • Congenital heart defects research
  • Single-cell and spatial transcriptomics
  • Genomics and chromatin dynamics
  • Developmental biology and gene regulation
  • MicroRNA in disease regulation
  • CRISPR and genetic engineering
  • Cancer-related molecular mechanisms research

Their contributions are documented in several significant journals and publication venues, particularly:

  • bioRxiv (Cold Spring Harbor Laboratory) with 12 publications
  • STAR Protocols with 4 publications
  • Nature Communications with 3 publications
  • eLife with 3 publications
  • Nature Genetics with 2 publications

Notable recent papers authored include:

  • "Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair," 2020, Nature Communications
  • "The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells," 2020, Cancer Cell
  • "Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder," 2020, Cell Stem Cell
  • "Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements," 2022, Nature Genetics
  • "Functional Heterogeneity within the Developing Zebrafish Epicardium," 2020, Developmental Cell

Frequent coauthors in their collaborative research efforts include:

  • Ruth M. Williams
  • Sarah Mayes
  • Paul R. Riley
  • Zhiyuan Hu
  • Martyna Lukoseviciute

Their prolific work in molecular biology and genetics encompasses single-cell sequencing techniques and experimental studies relevant to tissue regeneration, cancer biology, and developmental disorders. The research also addresses molecular mechanisms involved in congenital heart defects and chromatin regulation, reflecting a multidisciplinary approach integrating cutting-edge genomics and transcriptomics.

Best Publications

  • The amphioxus genome and the evolution of the chordate karyotype

    Nicholas H. Putnam;Thomas Butts;David E. K. Ferrier;Rebecca F. Furlong

  • A gene regulatory network orchestrates neural crest formation.

    Tatjana Sauka-Spengler;Marianne Bronner-Fraser

  • The African coelacanth genome provides insights into tetrapod evolution

    Chris T. Amemiya;Chris T. Amemiya;Jessica Alfoldi;Alison P. Lee;Shaohua Fan

  • Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution

    Jeramiah J. Smith;Shigehiro Kuraku;Carson Holt;Tatjana Sauka-Spengler

  • Genetic dissection of the α-globin super-enhancer in vivo

    Deborah Hay;Jim R. Hughes;Christian Babbs;James O.J. Davies

  • The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution.

    Jeramiah J. Smith;Nataliya Timoshevskaya;Chengxi Ye;Carson Holt

  • Assembling neural crest regulatory circuits into a gene regulatory network.

    Paola Betancur;Marianne Bronner-Fraser;Tatjana Sauka-Spengler

  • Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair

    Filipa C. Simões;Thomas J. Cahill;Amy Kenyon;Daria Gavriouchkina;Daria Gavriouchkina

  • Ancient evolutionary origin of the neural crest gene regulatory network.

    Tatjana Sauka-Spengler;Daniel Meulemans;Matthew Jones;Marianne Bronner-Fraser

  • Active DNA demethylation at enhancers during the vertebrate phylotypic period

    Ozren Bogdanović;Ozren Bogdanović;Ozren Bogdanović;Arne H Smits;Elisa de la Calle Mustienes;Juan J Tena

  • Mapping a multiplexed zoo of mRNA expression

    Harry M. T. Choi;Colby R. Calvert;Naeem Husain;David Huss

  • Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.

    Paola Falletta;Luis Sanchez-del-Campo;Jagat Chauhan;Maike Effern

  • Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest

    Paola Betancur;Marianne Bronner-Fraser;Tatjana Sauka-Spengler

  • The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells

    Zhiyuan Hu;Mara Artibani;Abdulkhaliq Alsaadi;Nina Wietek;Nina Wietek

  • Gain‐ and Loss‐of‐Function Approaches in the Chick Embryo

    Tatjana Sauka-Spengler;Meyer Barembaum

  • Dynamic and Differential Regulation of Stem Cell Factor FoxD3 in the Neural Crest Is Encrypted in the Genome

    Marcos S. Simões-Costa;Sonja J. McKeown;Joanne Tan-Cabugao;Tatjana Sauka-Spengler

  • Induction of the neural crest state: Control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions

    Maneeshi S. Prasad;Tatjana Sauka-Spengler;Carole LaBonne

  • Histone Demethylase JmjD2A Regulates Neural Crest Specification

    Pablo Hernan Strobl-Mazzulla;Tatjana Sauka-Spengler;Marianne Bronner-Fraser

  • Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder

    Hannah K. Long;Marco Osterwalder;Ian C. Welsh;Karissa Hansen

  • Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network

    Marcos Simões-Costa;Joanne Tan-Cabugao;Igor Antoshechkin;Tatjana Sauka-Spengler

Frequent Co-Authors

Marianne Bronner-Fraser
Marianne Bronner-Fraser California Institute of Technology
Chris T. Amemiya
Chris T. Amemiya University of California, Merced
J. Joshua Smith
J. Joshua Smith Memorial Sloan Kettering Cancer Center
Paul R. Riley
Paul R. Riley University of Oxford
James Hughes
James Hughes Emory University
Vincenzo Cerundolo
Vincenzo Cerundolo University of Oxford
Volker Tresp
Volker Tresp Ludwig-Maximilians-Universität München
Mark Yandell
Mark Yandell University of Utah
Greg Elgar
Greg Elgar Genomics England
Douglas R. Higgs
Douglas R. Higgs University of Oxford

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