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Biology and Biochemistry

D-Index
76
Citations
26656
World Ranking
4961
National Ranking
2383

Overview

J. Joshua Smith is a researcher affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their work primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with notable contributions in Molecular Biology, Genetics, Plant Science, Nature and Landscape Conservation, and Cancer Research.

Their research frequently addresses topics including:

  • Genomics and Phylogenetic Studies
  • Genetic diversity and population structure
  • Chromosomal and Genetic Variations
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Genetic and phenotypic traits in livestock
  • Fish Ecology and Management Studies
  • Aquaculture disease management and microbiota

J. Joshua Smith has published extensively, with notable recent papers such as:

  • "The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci", 2021, Proceedings of the National Academy of Sciences
  • "The hagfish genome and the evolution of vertebrates", 2024, Nature
  • "Early satellite cell communication creates a permissive environment for long-term muscle growth", 2021, iScience
  • "Programmed DNA Elimination in Vertebrates", 2020, Annual Review of Animal Biosciences
  • "Genomic islands of divergence infer a phenotypic landscape in Pacific lamprey", 2020, Molecular Ecology

Their publications have appeared in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Nature Ecology & Evolution
  • Data in Brief
  • Zenodo (CERN European Organization for Nuclear Research)

J. Joshua Smith's research collaborations include multiple co-authors with whom they have frequently published. These collaborators include:

  • Nataliya Timoshevskaya
  • S. Randal Voss
  • Vladimir A. Timoshevskiy
  • Ferdinand Marlétaz
  • Elise Parey

Best Publications

  • Nomograms in oncology: more than meets the eye

    Vinod P Balachandran;Mithat Gonen;J Joshua Smith;Ronald P DeMatteo

  • Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

    Jill C. Milne;Philip D. Lambert;Simon Schenk;David P. Carney

  • A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

    Sarah K Knutson;Tim J Wigle;Natalie M Warholic;Christopher J Sneeringer

  • The African coelacanth genome provides insights into tetrapod evolution

    Chris T. Amemiya;Chris T. Amemiya;Jessica Alfoldi;Alison P. Lee;Shaohua Fan

  • Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution

    Jeramiah J. Smith;Shigehiro Kuraku;Carson Holt;Tatjana Sauka-Spengler

  • Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer

    J. Joshua Smith;Natasha G. Deane;Fei Wu;Nipun B. Merchant

  • The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

    Ingo Braasch;Andrew R Gehrke;Jeramiah J Smith;Kazuhiko Kawasaki

  • Selective Inhibition of EZH2 by EPZ-6438 Leads to Potent Antitumor Activity in EZH2-Mutant Non-Hodgkin Lymphoma

    Sarah K. Knutson;Satoshi Kawano;Yukinori Minoshima;Natalie M. Warholic

  • Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.

    Andrea Cercek;Campbell S.D. Roxburgh;Campbell S.D. Roxburgh;Paul Strombom;J. Joshua Smith

  • A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

    Elayne Chan-Penebre;Kristy G Kuplast;Christina R Majer;P Ann Boriack-Sjodin

  • SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

    Takeshi Yoshizaki;Jill C. Milne;Takeshi Imamura;Simon Schenk

  • Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy

    J. Joshua Smith;Paul Strombom;Oliver S. Chow;Campbell S. Roxburgh;Campbell S. Roxburgh

  • A rectal cancer organoid platform to study individual responses to chemoradiation.

    Karuna Ganesh;Chao Wu;Kevin P. O’Rourke;Bryan C. Szeglin

  • Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP

    Amy K. Walker;Fajun Yang;Fajun Yang;Karen Jiang;Jun Yuan Ji;Jun Yuan Ji

  • Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management

    J. Joshua Smith;Oliver S. Chow;Marc J. Gollub;Garrett M. Nash

  • The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution.

    Jeramiah J. Smith;Nataliya Timoshevskaya;Chengxi Ye;Carson Holt

  • Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors.

    Cristina Valero;Mark Lee;Douglas Hoen;Kate Weiss

  • Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

    Justin M Balko;Rebecca S Cook;David B Vaught;María G Kuba

  • Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

    Jesse J Smith;Renée Deehan Kenney;David J Gagne;Brian P Frushour

  • Rapid spread of invasive genes into a threatened native species

    Benjamin M. Fitzpatrick;Jarrett R. Johnson;D. Kevin Kump;Jeramiah J. Smith

Frequent Co-Authors

Julio Garcia-Aguilar
Julio Garcia-Aguilar Memorial Sloan Kettering Cancer Center
Martin R. Weiser
Martin R. Weiser Memorial Sloan Kettering Cancer Center
Philip B. Paty
Philip B. Paty Memorial Sloan Kettering Cancer Center
Jose G. Guillem
Jose G. Guillem University of North Carolina at Chapel Hill
Jinru Shia
Jinru Shia Memorial Sloan Kettering Cancer Center
Xi Chen
Xi Chen University of California, Davis
Robert A. Copeland
Robert A. Copeland Accent Therapeutics (United States)
Chris T. Amemiya
Chris T. Amemiya University of California, Merced
Leonard Saltz
Leonard Saltz Memorial Sloan Kettering Cancer Center
Mithat Gonen
Mithat Gonen Memorial Sloan Kettering Cancer Center

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