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Best Scientists
2025

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Best Scientists

D-Index
175
Citations
126279
World Ranking
715
National Ranking
440

Medicine

D-Index
175
Citations
129049
World Ranking
428
National Ranking
257

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Edward G. Lakatta is affiliated with the National Institutes of Health in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed extensively to subfields including cardiology and cardiovascular medicine, molecular biology, cellular and molecular neuroscience, physiology, and cognitive neuroscience.

The primary focus of their work lies in cardiovascular health and disease, with particular emphasis on cardiac electrophysiology and arrhythmias, ion channel regulation and function, receptor mechanisms and signaling, cardiovascular health and disease prevention, neuroscience and neural engineering, cardiac fibrosis and remodeling, and heart rate variability and autonomic control.

Notable recent publications by Edward G. Lakatta include:

  • Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits, 2024, Nature Genetics
  • Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction, 2020, Circulation Research
  • The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular Disease, 2020, JAMA Cardiology
  • Synchronized Cardiac Impulses Emerge From Heterogeneous Local Calcium Signals Within and Among Cells of Pacemaker Tissue, 2020, JACC. Clinical electrophysiology
  • A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice, 2021, eLife

Edward G. Lakatta has collaborated frequently with several researchers, including:

  • Christopher H. Morrell
  • Victor A. Maltsev
  • Kirill V. Tarasov
  • Mingyi Wang
  • Ross A. McDevitt

Their work has been published predominantly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • The FASEB Journal
  • GeroScience
  • Alzheimer's & Dementia

Among recognized distinctions, Edward G. Lakatta is a member of the Association of American Physicians.

Best Publications

  • Resveratrol improves health and survival of mice on a high-calorie diet

    Joseph A. Baur;Kevin J. Pearson;Nathaniel O Price;Hamish A. Jamieson

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises Part I: Aging Arteries: A “Set Up” for Vascular Disease

    Edward G. Lakatta;Daniel Levy

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

    Angelo Scuteri;Serena Sanna;Wei-Min Chen;Manuela Uda

  • Newly identified loci that influence lipid concentrations and risk of coronary artery disease

    Cristen J. Willer;Serena Sanna;Anne U. Jackson;Angelo Scuteri

  • Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects

    Yoav Ben-Shlomo;Melissa Spears;Chris Boustred;Margaret May

  • Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part II: The Aging Heart in Health: Links to Heart Disease

    Edward G. Lakatta;Daniel Levy

  • Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults.

    Kim Sutton-Tyrrell;Samer S. Najjar;Robert M. Boudreau;Lakshmi Venkitachalam

  • Common variants at 30 loci contribute to polygenic dyslipidemia.

    Sekar Kathiresan;Sekar Kathiresan;Sekar Kathiresan;Cristen J. Willer;Gina M. Peloso;Serkalem Demissie

  • Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises. Part III: Cellular and molecular clues to heart and arterial aging

    Edward G. Lakatta

  • Effects of age and aerobic capacity on arterial stiffness in healthy adults.

    P. V. Vaitkevicius;J. L. Fleg;J. H. Engel;F. C. O'connor

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness: A Scientific Statement From the American Heart Association

    Raymond R. Townsend;Ian B. Wilkinson;Ernesto L. Schiffrin;Alberto P. Avolio

  • Accelerated Longitudinal Decline of Aerobic Capacity in Healthy Older Adults

    Jerome L. Fleg;Christopher H. Morrell;Christopher H. Morrell;Angelo G. Bos;Larry J. Brant

  • Cardiovascular regulatory mechanisms in advanced age.

    E G Lakatta

  • Normal Human Aging: The Baltimore Longitudinal Study on Aging

    Nathan W. Shock;Richard C. Greulich;Paul T Costa;Reubin Andres

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Luigi Ferrucci
Luigi Ferrucci National Institutes of Health
Rui-Ping Xiao
Rui-Ping Xiao Peking University
Jerome L. Fleg
Jerome L. Fleg National Institutes of Health
David Schlessinger
David Schlessinger National Institutes of Health
Bruce M. Psaty
Bruce M. Psaty University of Washington
Gary Gerstenblith
Gary Gerstenblith Johns Hopkins University
Heping Cheng
Heping Cheng Peking University
Maurizio C. Capogrossi
Maurizio C. Capogrossi Johns Hopkins University
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor

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