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Biology and Biochemistry

D-Index
62
Citations
13515
World Ranking
10816
National Ranking
831

Overview

Suzanne M. Watt is affiliated with the University of Oxford in the United Kingdom. Their research spans the disciplines of medicine and biochemistry, genetics, and molecular biology, with a focus on hematology, molecular biology, immunology, genetics, and cell biology as key subfields.

The main topics within their body of work include hematopoietic stem cell transplantation, acute myeloid leukemia research, immune cell function and interaction, single-cell and spatial transcriptomics, RNA research and splicing, RNA modifications and cancer, and protein degradation and inhibitors.

Frequent coauthors in their research collaborations include Irene Roberts, Hua Peng, Joanna Hester, George Adigbli, and Fadi Issa.

The scientist has published in several notable venues, with frequent contributions to Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, the International Journal of Molecular Sciences, Leukemia, Blood, and npj Regenerative Medicine.

Recent papers authored or coauthored by Suzanne M. Watt demonstrate a focus on cellular and molecular mechanisms in hematopoiesis and leukemia. These include:

  • SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications, 2020, Leukemia
  • The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes, 2020, Blood
  • The stem cell revolution: on the role of CD164 as a human stem cell marker, 2021, npj Regenerative Medicine
  • Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo, 2021, Frontiers in Immunology
  • The long and winding road: homeostatic and disordered haematopoietic microenvironmental niches: a narrative review., 2022, PubMed

Best Publications

  • Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment

    Myrtle Y. Gordon;Graham P. Riley;Suzanne M. Watt;Melvyn F. Greaves

  • Lineage promiscuity in hemopoietic differentiation and leukemia.

    M.F. Greaves;L.C. Chan;A.J.W. Furley;S.M. Watt

  • Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review.

    Enca Martin-Rendon;Enca Martin-Rendon;Susan J. Brunskill;Chris J. Hyde;Simon J. Stanworth

  • The Human AC133 Hematopoietic Stem Cell Antigen Is also Expressed in Epithelial Cells and Targeted to Plasma Membrane Protrusions

    Denis Corbeil;Katja Röper;Andrea Hellwig;Manuela Tavian

  • Redefined nomenclature for members of the carcinoembryonic antigen family.

    N. Beauchemin;P. Draber;G. Dveksler;P. Gold

  • Carcinoembryonic antigens (CD66) on epithelial cells and neutrophils are receptors for Opa proteins of pathogenic neisseriae.

    Mumtaz Virji;Katherine Makepeace;David J. P. Ferguson;Suzanne M. Watt

  • The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae.

    Mumtaz Virji;Suzanne M. Watt;Stephanie Barker;Katherine Makepeace

  • Siglecs: a family of sialic-acid binding lectins.

    P R Crocker;E A Clark;M Filbin;S Gordon

  • The angiogenic properties of mesenchymal stem/stromal cells and their therapeutic potential

    Suzanne M. Watt;Suzanne M. Watt;Francesca Gullo;Francesca Gullo;Mark van der Garde;Mark van der Garde;Mark van der Garde;Daniel Markeson;Daniel Markeson;Daniel Markeson

  • Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1.

    C.D. Buckley;R. Doyonnas;J.P. Newton;S.D. Blystone

  • 5-AZACYTIDINE-TREATED HUMAN MESENCHYMAL STEM/PROGENITOR CELLS DERIVED FROM UMBILICAL CORD, CORD BLOOD AND BONE MARROW DO NOT GENERATE CARDIOMYOCYTES IN VITRO AT HIGH FREQUENCIES

    E. Martin-Rendon;D. Sweeney;F. Lu;F. Lu;F. Lu;J. Girdlestone;J. Girdlestone

  • Critical determinants of host receptor targeting by Neisseria meningitidis and Neisseria gonorrhoeae: identification of Opa adhesiotopes on the N-domain of CD66 molecules.

    Mumtaz Virji;Debbie Evans;Andrea Hadfield;Fritz Grunert

  • Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy.

    Michalis Papadakis;Gina Hadley;Maria Xilouri;Lisa C Hoyte

  • Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo

    Climent Casals-Pascual;Oscar Kai;Joyce O. P. Cheung;Senani Williams

  • Transcriptional Profiling of Human Cord Blood CD133+ and Cultured Bone Marrow Mesenchymal Stem Cells in Response to Hypoxia

    Enca Martin‐Rendon;Enca Martin‐Rendon;Sarah J.M. Hale;Dacey Ryan;Dilair Baban

  • Distribution and epitope analysis of the cell membrane glycoprotein (HPCA-1) associated with human hemopoietic progenitor cells.

    S M Watt;K Karhi;K Gatter;A J Furley

  • The heparin binding PECAM-1 adhesion molecule is expressed by CD34+ hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes

    Suzanne M. Watt;Jill Williamson;Helen Genevier;Jon Fawcett

  • PECAM-1: Its Expression and Function as a Cell Adhesion Molecule on Hemopoietic and Endothelial Cells

    Suzanne M. Watt;Steve E. Gschmeissner;Paul A. Bates

  • A Comparison of Methods for Quantifying Angiogenesis in the Matrigel Assay In Vitro

    Cheen Peen Khoo;Kingsley Micklem;Suzanne M. Watt

  • Stem cell plasticity

    Enca Martin-Rendon;Suzanne M. Watt;Suzanne M. Watt

Frequent Co-Authors

adrian l harris
adrian l harris University of Oxford
Irene Roberts
Irene Roberts University of Oxford
David J. Roberts
David J. Roberts University of Oxford
Herman Waldmann
Herman Waldmann University of Oxford
Kieran Clarke
Kieran Clarke University of Oxford
Andrew C.W. Zannettino
Andrew C.W. Zannettino University of Adelaide
Keith M. Channon
Keith M. Channon University of Oxford
Jaap Jan Zwaginga
Jaap Jan Zwaginga Leiden University Medical Center
Thomas A. Milne
Thomas A. Milne University of Oxford
Jean-Pierre Levesque
Jean-Pierre Levesque University of Queensland

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