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Immunology

D-Index
56
Citations
9862
World Ranking
3752
National Ranking
258

Overview

Halvard Bonig is affiliated with Goethe University Frankfurt in Germany and has contributed extensively to the field of medicine, with a particular focus on oncology, immunology, hematology, genetics, and molecular biology. Their research primarily revolves around CAR-T cell therapy, hematopoietic stem cell transplantation, immune cell function and interaction, virus-based gene therapy, acute myeloid leukemia, T-cell and B-cell immunology, and mesenchymal stem cell research.

The scientist has published in a variety of specialized venues, with frequent contributions appearing in:

  • Blood
  • Journal of Translational Medicine
  • Bone Marrow Transplantation
  • Cells
  • Klinische Pädiatrie

Halvard Bonig's recent publications include:

  • Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA), 2021, Annals of Oncology
  • CARAMBA: a first-in-human clinical trial with SLAMF7 CAR-T cells prepared by virus-free Sleeping Beauty gene transfer to treat multiple myeloma, 2021, Gene Therapy
  • Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia, 2021, Blood
  • Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4, 2020, Frontiers in Immunology
  • Severe impairment of T-cell responses to BNT162b2 immunization in patients with multiple myeloma, 2021, Blood

Their frequent collaborators include:

  • Peter Bader
  • Erhard Seifried
  • Evelyn Ullrich
  • Eva Rettinger
  • Andrea Jarisch

The focus of Halvard Bonig's work in CAR-T cell therapy research is reflected by a substantial number of publications, with 80 dedicated to this topic alone. Other significant research areas include hematopoietic stem cell transplantation with 54 related publications and immune cell function and interaction with 50 publications.

In summary, the research profile centers on advanced therapeutic approaches in oncology and hematology, emphasizing cellular therapies and immune system interactions. The body of work spans molecular biology techniques and clinical applications in hematologic malignancies and immune response modulation.

Best Publications

  • Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE)

    Ibrahim Yakoub-Agha;Christian Chabannon;Peter Bader;Grzegorz W. Basak

  • Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

    Kurt Schönfeld;Christiane Sahm;Congcong Zhang;Sonja Naundorf

  • Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B.

    Wolfgang Miesbach;Karina Meijer;Michiel Coppens;Peter Kampmann

  • Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab

    Halvard B. Bonig;Annette Wundes;Kai-Hsin Chang;Sylvia Lucas

  • CAR T-cells targeting FLT3 have potent activity against FLT3 - ITD + AML and act synergistically with the FLT3-inhibitor crenolanib

    Hardikkumar Jetani;Irene Garcia-Cadenas;Thomas Nerreter;Simone Thomas

  • Spleen Size Is Significantly Influenced by Body Height and Sex: Establishment of Normal Values for Spleen Size at US with a Cohort of 1200 Healthy Individuals.

    Kai Uwe Chow;Beate Luxembourg;Erhard Seifried;Halvard Bonig

  • Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT

    M Neuenhahn;J Albrecht;M Odendahl;F Schlott

  • Standardization of Good Manufacturing Practice–compliant production of bone marrow–derived human mesenchymal stromal cells for immunotherapeutic applications

    Patrick Wuchter;Karen Bieback;Hubert Schrezenmeier;Martin Bornhäuser

  • CARAMBA: a first-in-human clinical trial with SLAMF7 CAR-T cells prepared by virus-free Sleeping Beauty gene transfer to treat multiple myeloma.

    Sabrina Prommersberger;Michael Reiser;Michael Reiser;Julia Beckmann;Sophia Danhof

  • The role of G-protein signaling in hematopoietic stem/progenitor cell mobilization

    Thalia Papayannopoulou;Gregory V. Priestley;Halvard Bonig;Betty Nakamoto

  • Epigenetic Regulation of Endothelial Lineage Committed Genes in Pro-Angiogenic Hematopoietic and Endothelial Progenitor Cells

    kisho ohtani;Georgios J. Vlachojannis;Masamichi Koyanagi;Jes Niels Boeckel

  • Hematopoietic stem cell mobilization: updated conceptual renditions.

    H Bonig;T Papayannopoulou

  • Mesenchymal stromal cells from pooled mononuclear cells of multiple bone marrow donors as rescue therapy in pediatric severe steroid-refractory graft-versus-host disease: a multicenter survey.

    Zyrafete Kuçi;Halvard Bönig;Hermann Kreyenberg;Milica Bunos

  • Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.

    Yao Te Hsieh;Eun Ji Gang;Huimin Geng;Eugene Park

  • Hoxa9 and Meis1 cooperatively induce addiction to Syk signaling by suppressing miR-146a in acute myeloid leukemia.

    S Mohr;C Doebele;F Comoglio;T Berg

  • Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.

    Halvard Bonig;Gregory V. Priestley;Thalia Papayannopoulou

  • Effective treatment of steroid and therapy-refractory acute graft-versus-host disease with a novel mesenchymal stromal cell product (MSC-FFM).

    Peter Bader;Zyrafete Kuçi;Shahrzad Bakhtiar;Oliver Basu

  • Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis—Lessons From Pharmacological and Genetic Models

    Darja Karpova;Halvard Bonig

  • High interleukin-10 serum levels are associated with fatal outcome in patients after bone marrow transplantation

    L Hempel;D Körholz;P Nussbaum;H Bönig

  • Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies

    Paulina Nowakowska;Paulina Nowakowska;Annette Romanski;Annette Romanski;Nicole Miller;Marcus Odendahl

  • Automatic interface-controlled apheresis collection of stem/progenitor cells: results from an autologous donor validation trial of a novel stem cell apheresis device.

    Peter Reinhardt;Susanne Brauninger;Heike Bialleck;Kristin Thorausch

Frequent Co-Authors

Erhard Seifried
Erhard Seifried German Red Cross
Peter Bader
Peter Bader Goethe University Frankfurt
Thomas Klingebiel
Thomas Klingebiel Goethe University Frankfurt
Thalia Papayannopoulou
Thalia Papayannopoulou University of Washington
Torsten Tonn
Torsten Tonn TU Dresden
Hubert Serve
Hubert Serve Goethe University Frankfurt
Winfried S. Wels
Winfried S. Wels Goethe University Frankfurt
Peter Lang
Peter Lang University of Bern
Hermann Einsele
Hermann Einsele University of Würzburg

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