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Thalia Papayannopoulou

Thalia Papayannopoulou

D-Index & Metrics

Biology and Biochemistry

D-Index
94
Citations
33110
World Ranking
2005
National Ranking
1093

Overview

Thalia Papayannopoulou is affiliated with the University of Washington in the United States. Their research primarily explores the fields of biochemistry, genetics, molecular biology, and medicine. Within these broader domains, their work focuses on genetics, molecular biology, physiology, endocrinology, diabetes and metabolism, and immunology.

The scientist has contributed extensively to virus-based gene therapy research, erythrocyte function and pathophysiology, CRISPR and genetic engineering, hemoglobinopathies and related disorders, RNA interference and gene delivery, blood disorders and treatments, and prenatal screening and diagnostics.

Frequent venues for their publications include Blood, Experimental Hematology, Molecular Therapy - Methods & Clinical Development, Blood Advances, and Haematologica.

  • Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors (2021), Molecular Therapy - Methods & Clinical Development
  • Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo (2021), Blood
  • Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements (2020), JCI Insight
  • Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice (2021), Blood Advances
  • Patients with hypercortisolemic Cushing disease possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis (2022), Haematologica

Thalia Papayannopoulou has collaborated frequently with several researchers, including Evangelia Yannaki, André Lieber, Sucheol Gil, Alister P. W. Funnell, and Anna Ritá Migliaccio.

Best Publications

  • A comparative encyclopedia of DNA elements in the mouse genome

    Feng Yue;Feng Yue;Yong Cheng;Alessandra Breschi;Jeff Vierstra

  • Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin.

    Kenneth Kaushansky;Si Lok;Richard D. Holly;Virginia C. Broudy

  • Hematopoietic commitment during embryonic stem cell differentiation in culture.

    G Keller;M Kennedy;T Papayannopoulou;M V Wiles

  • HEL cells: a new human erythroleukemia cell line with spontaneous and induced globin expression

    Paul Martin;Thalia Papayannopoulou

  • Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin

    Thalia Papayannopoulou;Betty Nakamoto

  • The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen.

    Thalia Papayannopoulou;Charles Craddock;Betty Nakamoto;Gregory V. Priestley

  • Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

    William C. Forrester;Susumu Takegawa;Thalia Papayannopoulou;George Stamatoyannopoulos

  • Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoprotein.

    Jose A. Lopez;Dominic W. Chung;Kazuo Fujikawa;Frederick S. Hagen

  • Efficient Gene Transfer into Human CD34+ Cells by a Retargeted Adenovirus Vector

    Dmitry M. Shayakhmetov;Thalia Papayannopoulou;George Stamatoyannopoulos;André Lieber

  • Lineage-specific expression of a human β -globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells

    Elaine A. Dzierzak;Thalia Papayannopoulou;Richard C. Mulligan

  • Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2.

    Richard E. Person;Feng Qian Li;Zhijun Duan;Kathleen F. Benson

  • Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice

    Tariq Enver;Natacha Raich;Allen J. Ebens;Thalia Papayannopoulou

  • Marrow transplantation for thalassaemia.

    E Donnall Thomas;E Donnall Thomas;E Donnall Thomas;Jean E Sanders;Jean E Sanders;Jean E Sanders;C Dean Buckner;C Dean Buckner;C Dean Buckner;Thalia Papayannopoulou;Thalia Papayannopoulou;Thalia Papayannopoulou

  • Deletion of α4 Integrins from Adult Hematopoietic Cells Reveals Roles in Homeostasis, Regeneration, and Homing

    Linda M. Scott;Gregory V. Priestley;Thalia Papayannopoulou

  • Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy

    K. Kaushansky;V. C. Broudy;A. Grossmann;J. Humes

  • Erythropoietin receptor characteristics on primary human erythroid cells

    Virginia C. Broudy;Nancy Lin;Martha Brice;Betty Nakamoto

  • Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells

    Elizabeth A. Sweeney;Hugues Lortat-Jacob;Gregory V. Priestley;Betty Nakamoto

  • Anti–VLA4/VCAM-1—Induced Mobilization Requires Cooperative Signaling Through the kit/mkit Ligand Pathway

    Thalia Papayannopoulou;Gregory V. Priestley;Betty Nakamoto

  • Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.

    Eun Young Choi;Emmanouil Chavakis;Marcus A. Czabanka;Harald F. Langer

  • Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization.

    Thalia Papayannopoulou

Frequent Co-Authors

Halvard Bonig
Halvard Bonig Goethe University Frankfurt
André Lieber
André Lieber University of Washington
George Stamatoyannopoulos
George Stamatoyannopoulos University of Washington
John A. Stamatoyannopoulos
John A. Stamatoyannopoulos University of Washington
Anna Rita Migliaccio
Anna Rita Migliaccio University of Bologna
Zsuzsanna Izsvák
Zsuzsanna Izsvák Max Delbrück Center for Molecular Medicine
Mark Groudine
Mark Groudine Fred Hutchinson Cancer Research Center
Brent L. Wood
Brent L. Wood University of Washington
Hans Peter Kiem
Hans Peter Kiem Fred Hutchinson Cancer Research Center
Frederick R. Appelbaum
Frederick R. Appelbaum Fred Hutchinson Cancer Research Center

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