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Molecular Biology
Netherlands
2026
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Genetics and Molecular Biology
Netherlands
2024

D-Index & Metrics

Molecular Biology

D-Index
137
Citations
64725
World Ranking
143
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Netherlands Leader Award
  • 2025 - Research.com Molecular Biology in Netherlands Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Netherlands Leader Award
  • 2023 - Research.com Molecular Biology in Netherlands Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Netherlands Leader Award
  • 1994 - Royal Netherlands Academy of Arts and Sciences
  • 1989 - Member of Academia Europaea

Overview

Frank Grosveld is affiliated with Erasmus University Rotterdam in the Netherlands. Their research spans multiple fields of study, primarily within Biochemistry, Genetics and Molecular Biology, and Medicine. Within these domains, they focus on subfields including Molecular Biology, Infectious Diseases, Genetics, Animal Science and Zoology, and Physiology.

Their main research topics cover a variety of specialized areas such as SARS-CoV-2 and COVID-19 research, Genomics and Chromatin Dynamics, RNA research and splicing, Animal Virus Infections Studies, Erythrocyte Function and Pathophysiology, Monoclonal and Polyclonal Antibodies Research, and COVID-19 Clinical Research Studies.

Frank Grosveld's publication record includes recent papers such as:

  • "A human monoclonal antibody blocking SARS-CoV-2 infection" (2020) published in Nature Communications
  • "A human monoclonal antibody blocking SARS-CoV-2 infection" (2020) published in bioRxiv (Cold Spring Harbor Laboratory)
  • "A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies" (2021) published in Nature Communications
  • "Transcriptional Regulation by (Super)Enhancers: From Discovery to Mechanisms" (2021) published in Annual Review of Genomics and Human Genetics
  • "Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection" (2020) published in Nature Communications

Frequent coauthors collaborating with Grosveld include Dubravka Drabek, Rien van Haperen, Berend-Jan Bosch, Frank J. M. van Kuppeveld, and Wentao Li.

Their work has appeared in a range of publication venues. The most common include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Research Square (Research Square), Methods in Molecular Biology, and Development.

Frank Grosveld has been recognized by professional scientific bodies, with awards such as membership in the Royal Netherlands Academy of Arts and Sciences in 1994 and as a Member of Academia Europaea in 1989.

Best Publications

  • Position-independent, high-level expression of the human β-globin gene in transgenic mice

    Frank Grosveld;Greet Blom van Assendelft;David R. Greaves;George Kollias

  • Looping and interaction between hypersensitive sites in the active β-globin locus

    Bas Tolhuis;Robert Jan Palstra;Erik Splinter;Frank Grosveld

  • A human monoclonal antibody blocking SARS-CoV-2 infection.

    Chunyan Wang;Wentao Li;Dubravka Drabek;Nisreen M.A. Okba

  • Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress

    Caroline Cheng;Dennie Tempel;Rien van Haperen;Arjen van der Baan

  • Development of hematopoietic stem cell activity in the mouse embryo

    Albrecht Müller;A. Medvinsky;John Strouboulis;Frank Grosveld

  • Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

    Marie Liesse Asselin-Labat;Kate D. Sutherland;Kate D. Sutherland;Holly Barker;Holly Barker;Richard Thomas

  • Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells.

    Jessica Zuin;Jesse R. Dixon;Michael I. J. A. van der Reijden;Zhen Ye;Zhen Ye

  • CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus

    Erik Splinter;Helen Heath;Jurgen Kooren;Robert-Jan Palstra

  • Gene expression-based classification of non-small cell lung carcinomas and survival prediction.

    Jun Hou;Joachim Aerts;Bianca den Hamer;Wilfred van IJcken

  • Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein)

    Tatiana Stepanova;Jenny Slemmer;Casper C. Hoogenraad;Gideon Lansbergen

  • Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

    P.P. Pandolfi;F. Sonati;R. Rivi;P. Mason

  • Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis.

    Pier Paolo Pandolfi;Pier Paolo Pandolfi;Matthew E. Roth;Alar Karis;Alar Karis;Mark W. Leonard

  • Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients

    Fred W. van Leeuwen;Dominique P. V. de Kleijn;Helma H. van den Hurk;Andrea Neubauer

  • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

    Beatriz Nuez;David Michalovich;A. Bygrave;Robert Ploemacher

  • Transcription Factor Sp1 Is Essential for Early Embryonic Development but Dispensable for Cell Growth and Differentiation

    Marisol Marin;Alar Karis;Pim Visser;Frank Grosveld

  • The beta-globin nuclear compartment in development and erythroid differentiation.

    Robert-Jan Palstra;Bas Tolhuis;Erik Splinter;Rian Nijmeijer

  • Role of PML in cell growth and the retinoic acid pathway

    Zhu Gang Wang;Laurent Delva;Laurent Delva;Mirella Gaboli;Mirella Gaboli;Roberta Rivi;Roberta Rivi

  • The transcription factor GATA6 is essential for early extraembryonic development.

    Manoussos Koutsourakis;An Langeveld;Roger Patient;Rosa Beddington

  • Transcription complex stability and chromatin dynamics in vivo

    Mark Wijgerde;Frank Grosveld;Frank Grosveld;Peter Fraser

  • CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

    Erik Splinter;Helen Heath;Jurgen Kooren;Robert-Jan Palstra

Frequent Co-Authors

Sjaak Philipsen
Sjaak Philipsen Erasmus University Rotterdam
Niels Galjart
Niels Galjart Erasmus University Rotterdam
Peter Fraser
Peter Fraser Florida State University
Boris Lenhard
Boris Lenhard Imperial College London
Anna Akhmanova
Anna Akhmanova Utrecht University
Wouter de Laat
Wouter de Laat Utrecht University
Dick Tibboel
Dick Tibboel Erasmus University Rotterdam
Joost Gribnau
Joost Gribnau Erasmus University Rotterdam

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