World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Best Scientists

D-Index
171
Citations
127078
World Ranking
829
National Ranking
498

Biology and Biochemistry

D-Index
173
Citations
131293
World Ranking
79
National Ranking
61

Medicine

D-Index
173
Citations
131224
World Ranking
473
National Ranking
280

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Pier Paolo Pandolfi is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research contributions span key areas in biochemistry, genetics, and molecular biology, with a total of 93 publications in these primary fields. Medicine is another significant field of study, contributing 46 publications.

Their work covers several subfields, including molecular biology, cancer research, infectious diseases, oncology, and pulmonary and respiratory medicine. Specific research topics frequently addressed by Pandolfi include cancer-related molecular mechanisms, RNA modifications and cancer, microRNA in disease regulation, SARS-CoV-2 and COVID-19 research, RNA research and splicing, cancer under hypoxic conditions and metabolic processes, as well as the PI3K/AKT/mTOR signaling pathway in cancer.

Pandolfi has coauthored numerous papers with other researchers, frequently collaborating with John G. Clohessy, Giuseppe Novelli, Wenyi Wei, Jing Liu, and Tuan M. Nguyen. Their publications appear in a range of scientific venues, including bioRxiv (Cold Spring Harbor Laboratory), Cell Research, Blood, UNC Libraries, and Nature Genetics.

Key recent publications include:

  • "Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses" (2020), published in Cell Research
  • "Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner" (2021), published in Advanced Science
  • "Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs" (2021), published in Genome Biology
  • "The Tug1 lncRNA locus is essential for male fertility" (2020), published in Genome Biology
  • "Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle" (2020), published in Cell Research

Pier Paolo Pandolfi has received recognition including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2017 and is a member of the Association of American Physicians.

Best Publications

  • A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

    Leonardo Salmena;Laura Poliseno;Yvonne Tay;Lev Kats

  • The multilayered complexity of ceRNA crosstalk and competition

    Yvonne Tay;John L Rinn;Pier Paolo Pandolfi

  • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

    Laura Poliseno;Leonardo Salmena;JiangWen Zhang;Brett S Carver

  • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

    Zhenbang Chen;Lloyd C. Trotman;David Shaffer;Hui Kuan Lin

  • The functions and regulation of the PTEN tumour suppressor

    Min Sup Song;Leonardo Salmena;Leonardo Salmena;Pier Paolo Pandolfi

  • The p66shc adaptor protein controls oxidative stress response and life span in mammals

    Enrica Migliaccio;Marco Giorgio;Simonetta Mele;Giuliana Pelicci

  • Pten is essential for embryonic development and tumour suppression.

    Antonio Di Cristofano;Barbara Pesce;Carlos Cordon-Cardo;Pier Paolo Pandolfi

  • Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

    M Botto;C Dell'Agnola;A E Bygrave;E M Thompson

  • Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

    Arkaitz Carracedo;Li Ma;Li Ma;Li Ma;Julie Teruya-Feldstein;Federico Rojo

  • Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

    Steven L. Soignet;Peter Maslak;Zhu-Gang Wang;Suresh Jhanwar

  • Phosphorylation and Functional Inactivation of TSC2 by Erk: Implications for Tuberous Sclerosis and Cancer Pathogenesis

    Li Ma;Zhenbang Chen;Hediye Erdjument-Bromage;Paul Tempst;Paul Tempst

  • The Multiple Roles of PTEN in Tumor Suppression

    Antonio Di Cristofano;Pier Paolo Pandolfi

  • Crystal Structure of the PTEN Tumor Suppressor: Implications for Its Phosphoinositide Phosphatase Activity and Membrane Association

    J.-O. Lee;Haijuan Yang;M.-M. Georgescu;A. Di Cristofano

  • Tenets of PTEN tumor suppression.

    Leonardo Salmena;Arkaitz Carracedo;Pier Paolo Pandolfi

  • Does the ribosome translate cancer

    Davide Ruggero;Pier Paolo Pandolfi

  • Cancer metabolism: fatty acid oxidation in the limelight

    Arkaitz Carracedo;Lewis C. Cantley;Pier Paolo Pandolfi

  • Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity

    Wen Hong Shen;Adayabalam S. Balajee;Jianli Wang;Hong Wu

  • Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

    Yvonne Tay;Lev Kats;Leonardo Salmena;Dror Weiss

  • Essential role of Plzf in maintenance of spermatogonial stem cells

    José A Costoya;Robin M Hobbs;Maria Barna;Giorgio Cattoretti

  • Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

    Rosa Bernardi;Pier Paolo Pandolfi

Frequent Co-Authors

Julie Teruya-Feldstein
Julie Teruya-Feldstein Icahn School of Medicine at Mount Sinai
Carlos Cordon-Cardo
Carlos Cordon-Cardo Icahn School of Medicine at Mount Sinai
Arkaitz Carracedo
Arkaitz Carracedo University of the Basque Country
Lewis C. Cantley
Lewis C. Cantley Harvard University
Wenyi Wei
Wenyi Wei Beth Israel Deaconess Medical Center
John M. Asara
John M. Asara Beth Israel Deaconess Medical Center
Sabina Signoretti
Sabina Signoretti Brigham and Women's Hospital
Paolo Salomoni
Paolo Salomoni German Center for Neurodegenerative Diseases
Hui Kuan Lin
Hui Kuan Lin Wake Forest University
Taha Merghoub
Taha Merghoub Cornell University

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