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Sarah E. O'Connor

Sarah E. O'Connor

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
14125
World Ranking
9705
National Ranking
707

Overview

Sarah E. O'Connor is affiliated with the Max Planck Society in Germany, where their research primarily focuses on biochemistry, genetics, and molecular biology. Their scholarly output includes 163 publications in these fields, with a strong emphasis on molecular biology, pharmacology, plant science, organic chemistry, and biochemistry.

The scientist's work covers several key topics related to plant biochemistry and natural products. These topics include alkaloids synthesis and pharmacology, plant tissue culture and regeneration, microbial natural products and biosynthesis, chemical synthesis and alkaloids, berberine and alkaloids research, and traditional and medicinal uses of the Annonaceae family.

Several recent papers illustrate their research focus and publication record. These include:

  • F1000Research, 2025, published in F1000Research
  • A microbial supply chain for production of the anti-cancer drug vinblastine, 2022, published in Nature
  • Single-cell multi-omics in the medicinal plant Catharanthus roseus, 2023, published in Nature Chemical Biology
  • Biosynthesis of strychnine, 2022, published in Nature
  • The evolutionary origins of the cat attractant nepetalactone in catnip, 2020, published in Science Advances

O'Connor frequently collaborates with several co-authors. These include Lorenzo Caputi with 44 joint publications, Vincent Courdavault with 30, Benke Hong with 24, Nicolas Papon with 23, and Yoko Nakamura with 21.

Their research has been disseminated through a variety of publication venues. The most frequent are bioRxiv (Cold Spring Harbor Laboratory) with 26 publications, Nature Chemical Biology with 7, HAL (Le Centre pour la Communication Scientifique Directe) with 6, Proceedings of the National Academy of Sciences with 5, and New Phytologist with 5.

Best Publications

  • Chemistry and biology of monoterpene indole alkaloid biosynthesis

    Sarah E. O'Connor;Justin J. Maresh

  • Effect of N-linked glycosylation on glycopeptide and glycoprotein structure.

    Barbara Imperiali;Sarah E O’Connor

  • De novo production of the plant-derived alkaloid strictosidine in yeast

    Stephanie Brown;Marc Clastre;Vincent Courdavault;Sarah E. O’Connor

  • An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

    Fernando Geu-Flores;Nathaniel H. Sherden;Vincent Courdavault;Vincent Burlat;Vincent Burlat

  • Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

    Frédéric H. Vaillancourt;Ellen Yeh;David A. Vosburg;David A. Vosburg;Sarah E. O'Connor;Sarah E. O'Connor

  • Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

    Lorenzo Caputi;Jakob Franke;Scott C. Farrow;Khoa Chung

  • Standards for plant synthetic biology: a common syntax for exchange of DNA parts.

    Nicola J. Patron;Nicola J. Patron;Diego Orzaez;Sylvestre Marillonnet;Heribert Warzecha

  • Modulation of protein structure and function by asparagine-linked glycosylation

    Sarah E. O'Connor;Barbara Imperiali

  • Genome‐guided investigation of plant natural product biosynthesis

    Franziska Kellner;Jeongwoon Kim;Bernardo J. Clavijo;John P. Hamilton

  • Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme.

    Justin J. Maresh;Lesley Ann Giddings;Anne Friedrich;Elke A. Loris

  • Integrating carbon–halogen bond formation into medicinal plant metabolism

    Weerawat Runguphan;Xudong Qu;Xudong Qu;Sarah E. O’Connor

  • The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

    Alex Van Moerkercke;Alex Van Moerkercke;Priscille Steensma;Fabian Schweizer;Fabian Schweizer;Jacob Pollier;Jacob Pollier

  • Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species.

    Elsa Gongora-Castillo;Kevin L. Childs;Greg Fedewa;John P. Hamilton

  • Opportunities in metabolic engineering to facilitate scalable alkaloid production.

    Effendi Leonard;Weerawat Runguphan;Sarah E. O'Connor;Kristala Jones Prather

  • Engineering of Secondary Metabolism.

    Sarah E O'Connor

  • Formation of β-Hydroxy Histidine in the Biosynthesis of Nikkomycin Antibiotics

    Huawei Chen;Brian K Hubbard;Sarah E O'Connor;Christopher T Walsh

  • A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus

    Lesley Ann Giddings;David K. Liscombe;John P. Hamilton;Kevin L. Childs

  • A molecular basis for glycosylation-induced conformational switching.

    Sarah E. O'Connor;Barbara Imperiali

  • A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology

    Arturo Casini;Fang Yuan Chang;Raissa Eluere;Andrew M. King

  • A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus.

    David K. Liscombe;Sarah E. O’Connor;Sarah E. O’Connor

Frequent Co-Authors

C. Robin Buell
C. Robin Buell University of Georgia
Vincent Burlat
Vincent Burlat Paul Sabatier University
Brieanne Vaillancourt
Brieanne Vaillancourt Michigan State University
Alain Goossens
Alain Goossens Ghent University
Douglas E. Soltis
Douglas E. Soltis University of Florida
Jacob Pollier
Jacob Pollier Ghent University
Kevin L. Childs
Kevin L. Childs Michigan State University
Anne Osbourn
Anne Osbourn John Innes Centre

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