World's Best Scientists 2026 revealed!
Award Badge
Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
117
Citations
71479
World Ranking
629
National Ranking
383

Medicine

D-Index
118
Citations
81767
World Ranking
3968
National Ranking
2170

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Sabina Signoretti is affiliated with Brigham and Women's Hospital in the United States. Their research spans multiple domains within medicine, with a particular emphasis on oncology, molecular biology, and immunology. Their work frequently addresses topics related to cancer treatment and diagnostics, notably focusing on renal and related cancers.

The scientist has contributed extensively to the understanding of renal cell carcinoma and cancer immunotherapy. Their primary topics of research include:

  • Renal cell carcinoma treatment
  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • Ferroptosis and cancer prognosis
  • Bladder and Urothelial Cancer Treatments
  • Renal and related cancers
  • CAR-T cell therapy research

Major fields of study for Signoretti's work include Medicine and Biochemistry, Genetics, and Molecular Biology. Within these, their notable subfields are:

  • Pulmonary and Respiratory Medicine
  • Oncology
  • Molecular Biology
  • Cancer Research
  • Immunology

They have a significant publication record in several scientific venues. Frequent publication venues include:

  • Journal of Clinical Oncology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Oncologist
  • Clinical Cancer Research

Their recent papers illustrate a focus on the interplay between tumor biology and the immune environment in advanced renal cell carcinoma. Selected recent publications are:

  • Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma, 2020, Nature Medicine
  • Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma, 2021, Cancer Cell
  • Progressive immune dysfunction with advancing disease stage in renal cell carcinoma, 2021, Cancer Cell
  • A pathology foundation model for cancer diagnosis and prognosis prediction, 2024, Nature
  • Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma, 2020, Clinical Cancer Research

Collaborative efforts feature prominently in their work, with frequent coauthors including:

  • Toni K. Choueiri
  • David A. Braun
  • David F. McDermott
  • Eliezer M. Van Allen
  • Thomas Denize

Best Publications

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • The landscape of somatic copy-number alteration across human cancers

    Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Renal cell carcinoma.

    James J. Hsieh;Mark P. Purdue;Sabina Signoretti;Charles Swanton

  • Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

    Bo Li;Eric Severson;Eric Severson;Jean Christophe Pignon;Haoquan Zhao

  • Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

    W. Marston Linehan;Paul T. Spellman;Christopher J. Ricketts;Chad J. Creighton

  • Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

    Diana Miao;Diana Miao;Claire A. Margolis;Claire A. Margolis;Wenhua Gao;Martin H. Voss;Martin H. Voss

  • High-throughput oncogene mutation profiling in human cancer

    Roman K. Thomas;Alissa C. Baker;Ralph M. DeBiasi;Ralph M. DeBiasi;Wendy Winckler;Wendy Winckler

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion

    Arnold H. Zea;Paulo C. Rodriguez;Michael B. Atkins;Claudia Hernandez

  • Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

    Priscilla K. Brastianos;Scott L. Carter;Scott L. Carter;Sandro Santagata;Sandro Santagata;Daniel P. Cahill

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

    Caleb F. Davis;Christopher J. Ricketts;Min Wang;Lixing Yang

  • Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis

    Shidong Jia;Zhenning Liu;Sen Zhang;Pixu Liu

  • p63 Is a Prostate Basal Cell Marker and Is Required for Prostate Development

    Sabina Signoretti;David Waltregny;James Dilks;Beth Isaac

  • The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

    Christopher J Ricketts;Aguirre A De Cubas;Huihui Fan;Christof C Smith

Frequent Co-Authors

Toni K. Choueiri
Toni K. Choueiri Harvard University
David F. McDermott
David F. McDermott Beth Israel Deaconess Medical Center
Massimo Loda
Massimo Loda Cornell University
Michael B. Atkins
Michael B. Atkins Georgetown University
Eliezer M. Van Allen
Eliezer M. Van Allen Harvard University
William G. Kaelin
William G. Kaelin Harvard University
Rameen Beroukhim
Rameen Beroukhim Harvard University
Levi A. Garraway
Levi A. Garraway Roche (United States)
Matthew Meyerson
Matthew Meyerson Harvard University
Gordon J. Freeman
Gordon J. Freeman Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're considering a career in medicine but are open to alternative healthcare fields, online degrees in nursing offer flexible and affordable options. Many students explore nurse practitioner programs online to gain advanced clinical skills and expand their scope of practice. These programs let working RNs advance their careers and even specialize in areas like family medicine or pediatrics.

For those looking to complete their bachelor's degree, the cheapest rn to bsn online programs can be completed while working, helping nurses upgrade their credentials affordably. Many people are also interested in the cheapest online dnp programs to pursue leadership, education, or clinical research roles, taking their impact on healthcare to the next level.

Costs are often a deciding factor. It's important to compare the average cost of rn to bsn programs, as tuition varies between institutions. Online pathways make it easier for healthcare professionals to balance work, education, and personal commitments while moving up the career ladder.

Best Scientists Citing Sabina Signoretti

Trending Scientists

Recently Published Articles