Zhu Chen

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in China Leader Award
• 2017 - Fellow of the American Academy of Arts and Sciences
• 2013 - Fellow of the Royal Society, United Kingdom
• 2006 - Member of Academia Europaea
• 2003 - Member of the National Academy of Sciences
• 1999 - Fellow, The World Academy of Sciences

Overview

Best Publications

• A Human Genome Diversity Cell Line Panel

  Howard M. Cann;Claudia De Toma;Lucien Cazes;Marie Fernande Legrand

  2346
  Citations

• Effectiveness of convalescent plasma therapy in severe COVID-19 patients.

  Kai Duan;Bende Liu;Cesheng Li;Huajun Zhang

  2160
  Citations

• Acute promyelocytic leukemia: from highly fatal to highly curable.

  Zhen-Yi Wang;Zhu Chen

  1655
  Citations

• In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

  Guo-Qiang Chen;Jun Zhu;Xue-Geng Shi;Jian-Hua Ni

  1169
  Citations

• Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL) : I. As2O3 exerts dose-dependent dual effects on APL cells

  Guo-Qiang Chen;Xue-Geng Shi;Wei Tang;Shu-Min Xiong

  1017
  Citations

• Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.

  Xiao-Jing Yan;Jie Xu;Zhao-Hui Gu;Chun-Ming Pan

  973
  Citations

• Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

  Zhu Chen;Nigel J. Brand;Alex Chen;Sai Juan Chen

  896
  Citations

• Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia

  Lan Wang;Guang Biao Zhou;Guang Biao Zhou;Ping Liu;Jun Hong Song

  874
  Citations

• Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML

  Xiao-Wei Zhang;Xiao-Jing Yan;Zi-Ren Zhou;Fei-Fei Yang

  861
  Citations

• Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

  Haitao Yang;Weiqing Xie;Xiaoyu Xue;Xiaoyu Xue;Kailin Yang;Kailin Yang

  773
  Citations

• All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia.

  Zhi-Xiang Shen;Zhan-Zhong Shi;Jing Fang;Bai-Wei Gu

  748
  Citations

• Molecular Evolution of the SARS Coronavirus, during the Course of the SARS Epidemic in China

  Jian Feng He;Guo Wen Peng;Jun Min;De Wen Yu

  695
  Citations

• Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients.

  Chao Niu;Hua Yan;Ting Yu;Hui-Ping Sun

  686
  Citations

• The Schistosoma japonicum genome reveals features of host-parasite interplay

  Yan Zhou;Huajun Zheng;Yangyi Chen;Lei Zhang

  644
  Citations

• Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2.

  Jiaqi Tang;Changjun Wang;Youjun Feng;Weizhong Yang

  626
  Citations

• Y-Chromosome Evidence for a Northward Migration of Modern Humans into Eastern Asia during the Last Ice Age

  Bing Su;Junhua Xiao;Peter Underhill;Ranjan Deka

  606
  Citations

• Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia

  Jun Zhu;Marcel H. M. Koken;Frédérique Quignon;Mounira K. Chelbi-Alix

  604
  Citations

• Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

  Zhu Chen

  598
  Citations

• Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

  Jiong Hu;Yuan Fang Liu;Chuan Feng Wu;Fang Xu

  541
  Citations

• Challenges to effective cancer control in China, India, and Russia

  Paul E. Goss;Kathrin Strasser-Weippl;Brittany L. Lee-Bychkovsky;Brittany L. Lee-Bychkovsky;Lei Fan;Lei Fan

  528
  Citations