2017 - Fellow of the American Academy of Arts and Sciences
2013 - Fellow of the Royal Society, United Kingdom
2006 - Member of Academia Europaea
2003 - Member of the National Academy of Sciences
1999 - Fellow, The World Academy of Sciences
Zhu Chen mainly investigates Acute promyelocytic leukemia, Genetics, Arsenic trioxide, Leukemia and Cancer research. His work carried out in the field of Acute promyelocytic leukemia brings together such families of science as Internal medicine and Tretinoin, Cellular differentiation. His research investigates the link between Genetics and topics such as Evolutionary biology that cross with problems in Haplotype and Y chromosome.
He combines subjects such as Combination therapy, Pathogenesis and Acute promyelocytic leukaemia with his study of Arsenic trioxide. His Leukemia research is multidisciplinary, incorporating perspectives in Myeloid and Myeloid leukemia. His Cancer research research incorporates elements of Mutation, Exome sequencing, Exome and Chemotherapy.
Zhu Chen mainly focuses on Cancer research, Acute promyelocytic leukemia, Leukemia, Molecular biology and Cell biology. His primary area of study in Cancer research is in the field of Myeloid leukemia. His biological study spans a wide range of topics, including Arsenic trioxide and Tretinoin, Cellular differentiation.
His Arsenic trioxide research incorporates themes from Gastroenterology and Internal medicine, Chemotherapy. In his research, CD34 is intimately related to Myeloid, which falls under the overarching field of Leukemia. His research integrates issues of Gene rearrangement, Chromosomal translocation, Fusion gene, Gene and Regulation of gene expression in his study of Molecular biology.
The scientist’s investigation covers issues in Cell biology, Cancer research, Leukemia, Haematopoiesis and Myeloid leukemia. His research in Cancer research intersects with topics in Mutation, Fusion gene, Acute promyelocytic leukemia, Promyelocytic leukemia protein and Genome. The Acute promyelocytic leukemia study combines topics in areas such as Internal medicine, Toxicity and Targeted therapy.
His studies in Leukemia integrate themes in fields like Myeloid and Immunophenotyping. His Myeloid leukemia research is multidisciplinary, incorporating elements of Molecular biology, Downregulation and upregulation and DOT1L. He interconnects Arsenic trioxide and Retinoic acid in the investigation of issues within Pharmacology.
Zhu Chen mostly deals with Cancer research, Leukemia, Internal medicine, Myeloid leukemia and Cell biology. His Cancer research study integrates concerns from other disciplines, such as Kinase activity, Targeted therapy, Gefitinib, Lung cancer and Promyelocytic leukemia protein. The concepts of his Leukemia study are interwoven with issues in Myeloid, Receptor, Immunophenotyping, CD19 and Immunotherapy.
His work deals with themes such as Gastroenterology and Antibody, which intersect with Internal medicine. His Myeloid leukemia research includes elements of Molecular biology and Downregulation and upregulation. His Gene expression research is multidisciplinary, relying on both Acute promyelocytic leukemia and Retinoic acid.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
A Human Genome Diversity Cell Line Panel
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Science (2002)
Acute promyelocytic leukemia: from highly fatal to highly curable.
Zhen-Yi Wang;Zhu Chen.
Blood (2008)
KCNQ1 gain-of-function mutation in familial atrial fibrillation
Yi-Han Chen;Shi-Jie Xu;Saı̈d Bendahhou;Xiao-Liang Wang.
Science (2003)
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
Guo-Qiang Chen;Jun Zhu;Xue-Geng Shi;Jian-Hua Ni.
Blood (1996)
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL) : I. As2O3 exerts dose-dependent dual effects on APL cells
Guo-Qiang Chen;Xue-Geng Shi;Wei Tang;Shu-Min Xiong.
Blood (1997)
Fusion between a novel Krüppel‐like zinc finger gene and the retinoic acid receptor‐alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.
Zhu Chen;Nigel J. Brand;Alex Chen;Sai Juan Chen.
The EMBO Journal (1993)
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
Xiao-Jing Yan;Jie Xu;Zhao-Hui Gu;Chun-Ming Pan.
Nature Genetics (2011)
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia
Lan Wang;Guang Biao Zhou;Guang Biao Zhou;Ping Liu;Jun Hong Song.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML
Xiao-Wei Zhang;Xiao-Jing Yan;Zi-Ren Zhou;Fei-Fei Yang.
Science (2010)
All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia.
Zhi-Xiang Shen;Zhan-Zhong Shi;Jing Fang;Bai-Wei Gu.
Proceedings of the National Academy of Sciences of the United States of America (2004)
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