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D-Index & Metrics

Molecular Biology

D-Index
51
Citations
12611
World Ranking
2485
National Ranking
58

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Joost Gribnau is affiliated with Erasmus University Rotterdam in the Netherlands. Their research primarily spans Biochemistry, Genetics, and Molecular Biology, with a significant number of publications also categorized under Medicine. Their subfields of study include Molecular Biology, Genetics, Cancer Research, Pediatrics, Perinatology and Child Health, and Pulmonary and Respiratory Medicine.

Their work covers a range of topics, notably Epigenetics and DNA Methylation, Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities, Renal and related cancers, CRISPR and Genetic Engineering, Genetics and Neurodevelopmental Disorders, Genomics and Chromatin Dynamics, and Cancer Genomics and Diagnostics.

Frequent publication venues for Joost Gribnau include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Clinical Epigenetics
  • Nature Communications
  • Scientific Reports

Some of the recent papers associated with or including Joost Gribnau are:

  • Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids (2020, Frontiers in Cell and Developmental Biology)
  • SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females (2021, The American Journal of Human Genetics)
  • Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation (2020, PLoS Pathogens)
  • Human kidney organoids produce functional renin (2020, Kidney International)
  • CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells (2021, Nature Cell Biology)

Joost Gribnau has collaborated frequently with several co-authors, including Ruben Boers, Joachim Boers, Wilfred F. J. van IJcken, Eric M. Bindels, and Beatrice F. Tan.

In recognition of their scientific contributions, Joost Gribnau has been named a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Spatial partitioning of the regulatory landscape of the X-inactivation centre

    Elphège P. Nora;Bryan R. Lajoie;Edda G. Schulz;Luca Giorgetti;Luca Giorgetti;Luca Giorgetti

  • Derivation of embryonic germ cells and male gametes from embryonic stem cells

    Niels Geijsen;Melissa Horoschak;Melissa Horoschak;Kitai Kim;Kitai Kim;Joost Gribnau

  • Intergenic Transcription and Developmental Remodeling of Chromatin Subdomains in the Human β-globin Locus

    Joost Gribnau;Karin Diderich;Sara Pruzina;Roberta Calzolari

  • The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

    Erik Splinter;Elzo de Wit;Elphège P. Nora;Petra Klous

  • Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

    Detlev Biniszkiewicz;Joost Gribnau;Bernard Ramsahoye;François Gaudet;François Gaudet

  • The role of EKLF in human beta-globin gene competition.

    Mark Wijgerde;Joost Gribnau;Tolleiv Trimborn;Beatriz Nuez

  • A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells

    Christa Buecker;Hsu Hsin Chen;Jose Maria Polo;Laurence Daheron

  • RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation

    Iris Jonkers;Tahsin Stefan Barakat;Eskeatnaf Mulugeta Achame;Kim Monkhorst

  • RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

    Cristina Gontan;Eskeatnaf Mulugeta Achame;Jeroen Demmers;Tahsin Stefan Barakat

  • CTCF regulates cell cycle progression of αβ T cells in the thymus

    Helen Heath;Claudia Ribeiro de Almeida;Frank Sleutels;Gemma Dingjan

  • A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells

    Nilhan Gunhanlar;G. Shpak;M. van der Kroeg;LA Gouty-Colomer

  • Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci.

    Tolleiv Trimborn;Joost Gribnau;Frank Grosveld;Peter Fraser

  • X inactivation Xplained

    Anton Wutz;Joost Gribnau

  • X Chromosome Inactivation Is Initiated in Human Preimplantation Embryos

    Ilse M. van den Berg;Joop S.E. Laven;Mary Stevens;Iris Jonkers

  • X Inactivation Counting and Choice Is a Stochastic Process: Evidence for Involvement of an X-Linked Activator

    Kim Monkhorst;Iris Jonkers;Eveline Rentmeester;Frank Grosveld

  • Xist regulation and function eXplored

    Daphne B. Pontier;Joost Gribnau

  • RNF12 activates Xist and is essential for X chromosome inactivation.

    Tahsin Stefan Barakat;Nilhan Gunhanlar;Cristina Gontan Pardo;Eskeatnaf Mulugeta Achame

  • Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization

    Joost Gribnau;Konrad Hochedlinger;Ken Hata;En Li

  • Chromatin interaction mechanism of transcriptional control in vivo

    Joost Gribnau;Ernie de Boer;Tolleiv Trimborn;Mark Wijgerde

  • Expression Pattern of the Rett Syndrome Gene MeCP2 in Primate Prefrontal Cortex

    Schahram Akbarian;Schahram Akbarian;Richard Z Chen;Joost Gribnau;Theodore P Rasmussen

Frequent Co-Authors

Frank Grosveld
Frank Grosveld Erasmus University Rotterdam
Edith Heard
Edith Heard Collège de France
J. Anton Grootegoed
J. Anton Grootegoed Erasmus University Rotterdam
Peter Fraser
Peter Fraser Florida State University
Joop S.E. Laven
Joop S.E. Laven Erasmus University Rotterdam
Martin J. Hoogduijn
Martin J. Hoogduijn Erasmus University Rotterdam
Carla C. Baan
Carla C. Baan Erasmus University Rotterdam
Stefan Sleijfer
Stefan Sleijfer Erasmus University Rotterdam
Emmanuel Barillot
Emmanuel Barillot Institute Curie

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