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Immunology

D-Index
62
Citations
11702
World Ranking
3164
National Ranking
123

Overview

Martin J. Hoogduijn is affiliated with Erasmus University Rotterdam in the Netherlands. Their research output spans several interconnected fields in biomedical science, with a focus on medicine and biochemistry, genetics, and molecular biology. The main subfields of their work include surgery, molecular biology, genetics, transplantation, and pulmonary and respiratory medicine.

The core topics covered in Hoogduijn's research involve:

  • Mesenchymal stem cell research
  • Organ transplantation techniques and outcomes
  • Renal transplantation outcomes and treatments
  • Renal and related cancers
  • Tissue engineering and regenerative medicine
  • Extracellular vesicles in disease
  • Renal cell carcinoma treatment

They have published frequently in a range of scientific journals and venues, including:

  • Transplantation (11 publications)
  • Cytotherapy (8 publications)
  • Frontiers in Immunology (5 publications)
  • Transplant International (4 publications)
  • Scientific Reports (3 publications)

Recent publications authored or co-authored by Hoogduijn reflect active involvement in multiple aspects of stem cell and kidney research. Representative papers include:

  • "Editorial: Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies," 2020, Frontiers in Immunology
  • "Human kidney organoids produce functional renin," 2020, Kidney International
  • "Safety and feasibility of 2 h of normothermic machine perfusion of donor kidneys in the Eurotransplant Senior Program," 2021, BJS Open
  • "Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system," 2022, Scientific Reports
  • "An imaging flow cytometry-based methodology for the analysis of single extracellular vesicles in unprocessed human plasma," 2022, Communications Biology

In terms of collaborative work, Hoogduijn has frequent co-authors who contribute substantially to their research network. These include:

  • Carla C. Baan (40 collaborations)
  • Robert C. Minnee (19 collaborations)
  • Marlies E. J. Reinders (18 collaborations)
  • Sander S. Korevaar (16 collaborations)
  • Ana Merino (16 collaborations)

Across their research portfolio, Hoogduijn engages deeply with clinical and translational approaches within medicine, emphasizing transplantation surgery and regenerative therapies. Their work, often published in specialized biomedical journals, provides data-driven insights into mesenchymal stem cell therapies, organoid modeling, and renal transplant strategies.

Best Publications

  • Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion.

    Elke Eggenhofer;Volker Benseler;Alexander Kroemer;Felix Popp

  • Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells.

    Samantha F.H. de Witte;Franka Luk;Jesus M. Sierra Parraga;Madhu Gargesha

  • The life and fate of mesenchymal stem cells

    Elke Eggenhofer;Franka Luk;Marc H. Dahlke;Martin J. Hoogduijn

  • Multipotent Stromal Cells Induce Human Regulatory T Cells Through a Novel Pathway Involving Skewing of Monocytes Toward Anti-inflammatory Macrophages

    Sara M. Melief;Ellen Schrama;Martijn H. Brugman;Machteld M. Tiemessen

  • Embryonic Stem Cell Marker Expression Pattern in Human Mesenchymal Stem Cells Derived from Bone Marrow, Adipose Tissue, Heart and Dermis

    Una Riekstina;Inese Cakstina;Vadims Parfejevs;Martin Hoogduijn

  • THE IMMUNOMODULATORY PROPERTIES OF MESENCHYMAL STEM CELLS AND THEIR USE FOR IMMUNOTHERAPY

    Martin J. Hoogduijn;Felix Popp;Richard Verbeek;Mojgan Masoodi

  • Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells.

    Janis Ancans;Desmond J. Tobin;Martin J. Hoogduijn;Nico P. Smit

  • Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation

    Patricia Luz-Crawford;Farida Djouad;Farida Djouad;Karine Toupet;Karine Toupet;Claire Bony;Claire Bony

  • Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells.

    M. J. Crop;C. C. Baan;S. S. Korevaar;J. N. M. IJzermans

  • Human Heart, Spleen, and Perirenal Fat-Derived Mesenchymal Stem Cells Have Immunomodulatory Capacities

    M.J. Hoogduijn;M.J. Crop;A.M.A. Peeters;G.J.V.M. Van Osch

  • Human adipose tissue-derived mesenchymal stem cells abrogate plasmablast formation and induce regulatory B cells independently of T helper cells.

    Marcella Franquesa;Fane Mensah;Ruth Huizinga;Tanja Strini

  • Immunomodulatory effect of mesenchymal stem cells on B cells.

    Marcella Franquesa;Martin Johannes Hoogduijn;Oriol Bestard;Josep M Grinyó

  • Mesenchymal stem cell-educated macrophages

    Elke Eggenhofer;Martin J Hoogduijn

  • Cryopreserved or Fresh Mesenchymal Stromal Cells: Only a Matter of Taste or Key to Unleash the Full Clinical Potential of MSC Therapy?

    Guido Moll;Sven Geißler;Rusan Catar;Lech Ignatowicz

  • Comparative characterization of hair follicle dermal stem cells and bone marrow mesenchymal stem cells.

    Martin J Hoogduijn;Erwin Gorjup;Paul G Genever

  • Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes

    Sally James;James Fox;Farinaz Afsari;Jennifer Lee

  • Effects of hypoxia on the immunomodulatory properties of adipose tissue-derived mesenchymal stem cells

    Marieke Roemeling-van Rhijn;Fane K. F. Mensah;Sander S. Korevaar;Maarten J. Leijs

  • Inactivated Mesenchymal Stem Cells Maintain Immunomodulatory Capacity

    Franka Luk;Samantha F H de Witte;Sander S Korevaar;Marieke Roemeling-van Rhijn

  • Long-Term Expansion, Enhanced Chondrogenic Potential, and Suppression of Endochondral Ossification of Adult Human MSCs via WNT Signaling Modulation

    Roberto Narcisi;Mairéad A. Cleary;Mairéad A. Cleary;Pieter A.J. Brama;Martin J. Hoogduijn

  • Donor-derived mesenchymal stem cells suppress alloreactivity of kidney transplant patients.

    Meindert J. Crop;Carla C. Baan;Sander S. Korevaar;Jan N.M. IJzermans

  • Human adipose tissue-derived mesenchymal stem cells induce explosive T-Cell proliferation

    Meindert J. Crop;Carla C. Baan;Sander S. Korevaar;Jan N.M. Ijzermans

  • Mesenchymal Stromal Cells Anno 2019: Dawn of the Therapeutic Era? Concise Review

    Martin J. Hoogduijn;Eleuterio Lombardo

Frequent Co-Authors

Carla C. Baan
Carla C. Baan Erasmus University Rotterdam
Willem Weimar
Willem Weimar Erasmus University Rotterdam
Jan N. M. IJzermans
Jan N. M. IJzermans Erasmus University Rotterdam
Rutger J. Ploeg
Rutger J. Ploeg University of Oxford
Philip N. Newsome
Philip N. Newsome University of Birmingham
Luc J. W. van der Laan
Luc J. W. van der Laan Erasmus University Rotterdam
Hans J. Schlitt
Hans J. Schlitt University of Regensburg
Josep M. Grinyó
Josep M. Grinyó University of Barcelona
Ton J. Rabelink
Ton J. Rabelink Leiden University Medical Center
Edward K. Geissler
Edward K. Geissler University of Regensburg

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