Edward K. Geissler

Best Publications

• LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

  Almut Brand;Katrin Singer;Gudrun E. Koehl;Marlene Kolitzus

  1850
  Citations

• Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion.

  Elke Eggenhofer;Volker Benseler;Alexander Kroemer;Felix Popp

  874
  Citations

• Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation.

  Markus Guba;Christian Graeb;Karl-Walter Jauch;Edward K. Geissler

  454
  Citations

• Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment.

  Kathrin Renner;Katrin Singer;Gudrun E. Koehl;Edward K. Geissler

  424
  Citations

• Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

  Birgit Sawitzki;Paul N Harden;Petra Reinke;Aurélie Moreau

  411
  Citations

• Immunomodulatory effects of mesenchymal stem cells in a rat organ transplant model.

  Seiichiro Inoue;Felix C Popp;Gudrun E Koehl;Pompiliu Piso

  364
  Citations

• Induction of IL-13 Triggers TGF-β1-Dependent Tissue Fibrosis in Chronic 2,4,6-Trinitrobenzene Sulfonic Acid Colitis

  Stefan Fichtner-Feigl;Stefan Fichtner-Feigl;Ivan J. Fuss;Cheryl A. Young;Tomohiro Watanabe

  277
  Citations

• Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

  James A. Hutchinson;James A. Hutchinson;Paloma Riquelme;Paloma Riquelme;Birgit Sawitzki;Birgit Sawitzki;Stefan Tomiuk;Stefan Tomiuk

  275
  Citations

• Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate.

  F.C. Popp;E. Eggenhofer;P. Renner;P. Slowik

  263
  Citations

• Standardization of whole blood immune phenotype monitoring for clinical trials: panels and methods from the ONE study

  Mathias Streitz;Tewfik Miloud;Michael Kapinsky;Michael R Reed

  234
  Citations

• IL-13 Signaling via IL-13Rα2 Induces Major Downstream Fibrogenic Factors Mediating Fibrosis in Chronic TNBS Colitis

  Stefan Fichtner-Feigl;Cheryl A Young;Atsushi Kitani;Edward K Geissler

  209
  Citations

• Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.

  Sven A. Lang;Christian Moser;Andreas Gaumann;Dagmar Klein

  194
  Citations

• Hurdles in therapy with regulatory T cells

  Piotr Trzonkowski;Rosa Bacchetta;Manuela Battaglia;David Berglund

  171
  Citations

• Conversion of Th17 into IL-17A(neg) regulatory T cells: a novel mechanism in prolonged allograft survival promoted by mesenchymal stem cell-supported minimized immunosuppressive therapy.

  Nataša Obermajer;Felix C. Popp;Yorick Soeder;Jan Haarer

  169
  Citations

• IFN-γ-induced iNOS expression in mouse regulatory macrophages prolongs allograft survival in fully immunocompetent recipients.

  Unknown

  169
  Citations

• Inhibition of heat shock protein 90 impairs epidermal growth factor–mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo

  Sven A. Lang;Dagmar Klein;Christian Moser;Andreas Gaumann

  167
  Citations

• A primary tumor promotes dormancy of solitary tumor cells before inhibiting angiogenesis.

  Markus Guba;Grigore Cernaianu;Gudrun Koehl;Edward K. Geissler

  164
  Citations

• Targeting FGFR/PDGFR/VEGFR impairs tumor growth, angiogenesis, and metastasis by effects on tumor cells, endothelial cells, and pericytes in pancreatic cancer

  Johannes Taeger;Christian Moser;Claus Hellerbrand;Maria E Mycielska

  162
  Citations

• Mesenchymal stem cells require a sufficient, ongoing immune response to exert their immunosuppressive function.

  P. Renner;E. Eggenhofer;A. Rosenauer;F.C. Popp

  160
  Citations

• The ONE Study compares cell therapy products in organ transplantation: introduction to a review series on suppressive monocyte-derived cells.

  Edward K Geissler

  153
  Citations