Claus Hellerbrand

Overview

Best Publications

• Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

  Patricio Godoy;Nicola J. Hewitt;Ute Albrecht;Melvin E. Andersen

  1158
  Citations

• A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

  Stephan Buch;Felix Stickel;Eric Trépo;Michael Way

  580
  Citations

• NFkappaB prevents apoptosis and liver dysfunction during liver regeneration.

  Y Iimuro;T Nishiura;C Hellerbrand;K E Behrns

  545
  Citations

• Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes

  Katrin Dietl;Kathrin Renner;Katja Dettmer;Birgit Timischl

  493
  Citations

• Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

  Peter Dietrich;Claus Hellerbrand

  491
  Citations

• The role of TGFβ1 in initiating hepatic stellate cell activation in vivo

  Claus Hellerbrand;Branko Stefanovic;Branko Stefanovic;Branko Stefanovic;Frank Giordano;Frank Giordano;Frank Giordano;Elmar R Burchardt;Elmar R Burchardt;Elmar R Burchardt

  472
  Citations

• Intestinal fungi contribute to development of alcoholic liver disease

  An Ming Yang;Tatsuo Inamine;Tatsuo Inamine;Katrin Hochrath;Peng Chen

  465
  Citations

• PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

  Marcus Mühlbauer;Martin Fleck;Christian Schütz;Thomas Weiss

  451
  Citations

• Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis

  Oliver Krenkel;Tobias Puengel;Olivier Govaere;Ali T. Abdallah

  442
  Citations

• GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis

  Thomas Amann;Ulrike Maegdefrau;Arndt Hartmann;Abbas Agaimy

  385
  Citations

• Functional Contribution of Elevated Circulating and Hepatic Non-Classical CD14+CD16+ Monocytes to Inflammation and Human Liver Fibrosis

  Henning W. Zimmermann;Sebastian Seidler;Jacob Nattermann;Nikolaus Gassler

  373
  Citations

• Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans

  Sonja Hillebrandt;Sonja Hillebrandt;Hermann E Wasmuth;Ralf Weiskirchen;Claus Hellerbrand

  356
  Citations

• DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

  Erwin Gäbele;Karin Dostert;Claudia Hofmann;Reiner Wiest

  336
  Citations

• Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

  Thomas Amann;Frauke Bataille;Thilo Spruss;Marcus Mühlbauer

  324
  Citations

• Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells.

  Hella Wobser;Christoph Dorn;Thomas S Weiss;Thomas Amann

  298
  Citations

• Ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhosis

  Michael Schepke;Gerhard Kleber;Dieter Nürnberg;Jörg Willert

  295
  Citations

• Inhibition of Proinflammatory Molecule Production by Adenovirus-Mediated Expression of a Nuclear Factor κB Super-Repressor in Human Intestinal Epithelial Cells

  Christian Jobin;Asit Panja;Claus Hellerbrand;Yuji Iimuro

  279
  Citations

• Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells.

  B Stefanovic;C Hellerbrand;M Holcik;M Briendl

  279
  Citations

• Animal models of chronic liver diseases.

  Yan Liu;Christoph Meyer;Chengfu Xu;Honglei Weng

  256
  Citations

• 1183 GENETIC VARIATION IN THE PNPLA3 GENE IS ASSOCIATED WITH ALCOHOLIC LIVER INJURY IN CAUCASIANS

  F. Stickel;S. Buch;K. Lau;H. Meyer zu Schwabedissen

  2
  Citations