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Carla Ghelardini

Carla Ghelardini

D-Index & Metrics

Chemistry

D-Index
69
Citations
16067
World Ranking
6230
National Ranking
136

Overview

Carla Ghelardini is affiliated with the University of Florence in Italy and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their published work spans multiple subfields including molecular biology, physiology, pharmacology, organic chemistry, and oncology.

The main topics investigated by Ghelardini encompass pain mechanisms and treatments, cancer treatment and pharmacology, enzyme function and inhibition, pharmacological effects of natural compounds, adenosine and purinergic signaling, cholinesterase and neurodegenerative diseases, and gastrointestinal motility and disorders.

Frequent publication venues for Carla Ghelardini include:

  • International Journal of Molecular Sciences
  • European Journal of Medicinal Chemistry
  • Pharmaceutics
  • Frontiers in Pharmacology
  • Journal of Medicinal Chemistry

Some of the recent notable papers authored or co-authored by Carla Ghelardini include:

  • Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients, 2020, Microbiome
  • The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1, 2020, Oxidative Medicine and Cellular Longevity
  • Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10, 2021, Journal of Clinical Investigation
  • VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody, 2021, Journal of Experimental & Clinical Cancer Research
  • Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist, 2020, Frontiers in Pharmacology

Frequent collaborators in Carla Ghelardini's research include:

  • Lorenzo Di Cesare Mannelli
  • Laura Micheli
  • Elena Lucarini
  • Alessandra Toti
  • Alessandra Pacini

Ghelardini's research output is characterized by interdisciplinary approaches combining molecular biology and pharmacology to address issues related to pain, cancer, enzyme functions, and the biological actions of natural compounds.

Best Publications

  • MENTHOL: A NATURAL ANALGESIC COMPOUND

    Nicoletta Galeotti;Lorenzo Di Cesare Mannelli;Gabriela Mazzanti;Alessandro Bartolini

  • Local anaesthetic activity of β-caryophyllene ☆

    C. Ghelardini;N. Galeotti;L. Di Cesare Mannelli;G. Mazzanti

  • Local Anaesthetic Activity of the Essential Oil of Lavandula angustifolia

    Carla Ghelardini;Nicoletta Galeotti;Giuseppe Salvatore;Gabriela Mazzanti

  • Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients.

    Alfonsina D’Amato;Lorenzo Di Cesare Mannelli;Elena Lucarini;Angela L. Man

  • A Smart Platform for Hyperthermia Application in Cancer Treatment: Cobalt-Doped Ferrite Nanoparticles Mineralized in Human Ferritin Cages

    Elvira Fantechi;Claudia Innocenti;Matteo Zanardelli;Maria Fittipaldi

  • Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh.

    Piero Dolara;Barbara Corte;Carla Ghelardini;Anna Maria Pugliese

  • Development, characterization and in vivo evaluation of benzocaine-loaded liposomes.

    Paola Mura;Francesca Maestrelli;Maria Luisa González-Rodríguez;Ilaria Michelacci

  • Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism. Protective effect of silibinin.

    Lorenzo Di Cesare Mannelli;Matteo Zanardelli;Paola Failli;Carla Ghelardini

  • Morphologic Features and Glial Activation in Rat Oxaliplatin-Dependent Neuropathic Pain

    Lorenzo Di Cesare Mannelli;Alessandra Pacini;Laura Bonaccini;Matteo Zanardelli

  • Role of histamine in rodent antinociception.

    Petra Malmberg-Aiello;Claudia Lamberti;Carla Ghelardini;Alberto Giotti

  • Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

    Haylie K. Romero;Sean B. Christensen;Lorenzo Di Cesare Mannelli;Joanna Gajewiak

  • Role of muscarinic receptor subtypes in central antinociception.

    A. Bartolini;C. Ghelardini;L. Fantetti;M. Malcangio

  • A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects

    Fabrizio Carta;Lorenzo Di Cesare Mannelli;Melissa Pinard;Carla Ghelardini

  • Glial role in oxaliplatin-induced neuropathic pain

    Lorenzo Di Cesare Mannelli;Alessandra Pacini;Laura Micheli;Alessia Tani

  • Design, characterization and in vivo evaluation of nanostructured lipid carriers (NLC) as a new drug delivery system for hydrochlorothiazide oral administration in pediatric therapy.

    Marzia Cirri;Lavinia Maestrini;Francesca Maestrelli;Natascia Mennini

  • Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism

    L. Di Cesare Mannelli;G. D'Agostino;A. Pacini;R. Russo

  • Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs.

    Fulvio Gualtieri;Dina Manetti;Maria Novella Romanelli;Carla Ghelardini

  • [(3-Chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents.

    Maria Paola Giovannoni;Claudia Vergelli;Carla Ghelardini;Nicoletta Galeotti

  • Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis.

    Silvia Bua;Lorenzo Di Cesare Mannelli;Daniela Vullo;Carla Ghelardini

  • The pharmacological basis of opioids.

    Ghelardini C;Di Cesare Mannelli L;Bianchi E

  • Local anaesthetic activity of monoterpenes and phenylpropanes of essential oils.

    Carla Ghelardini;Nicoletta Galeotti;Gabriela Mazzanti

  • Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels.

    Lorenzo Di Cesare Mannelli;Elena Lucarini;Laura Micheli;Ilaria Mosca

  • Oxaliplatin-induced oxidative stress in nervous system-derived cellular models: Could it correlate with in vivo neuropathy?

    L. Di Cesare Mannelli;M. Zanardelli;P. Failli;C. Ghelardini

  • Development of solid lipid nanoparticles as carriers for improving oral bioavailability of glibenclamide.

    L.M.D. Gonçalves;F. Maestrelli;L. Di Cesare Mannelli;C. Ghelardini

  • Local anaesthetic activity of (+)- and (-)-menthol.

    Nicoletta Galeotti;Carla Ghelardini;Lorenzo Di Cesare Mannelli;Gabriela Mazzanti

  • CGP 35348, a new GABAB antagonist, prevents antinociception and muscle-relaxant effect induced by baclofen.

    M. Malcangio;C. Ghelardini;A. Giotti;P. Malmberg-Aiello

Frequent Co-Authors

Nicoletta Galeotti
Nicoletta Galeotti University of Florence
Anna Rita Bilia
Anna Rita Bilia University of Florence
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Lidia Sautebin
Lidia Sautebin University of Naples Federico II
Fabrizio Carta
Fabrizio Carta University of Florence
Paola Mura
Paola Mura University of Florence
Alessandro Quattrone
Alessandro Quattrone University of Trento
Claudia Martini
Claudia Martini University of Pisa
Katia Varani
Katia Varani University of Ferrara
Stefano Pallanti
Stefano Pallanti Albert Einstein College of Medicine

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