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Chemistry

D-Index
71
Citations
21344
World Ranking
5463
National Ranking
68

Research.com Recognitions

  • 1998 - Member of Academia Europaea
  • 1997 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Rudolf Rigler is affiliated with the Karolinska Institute in Sweden and has contributed to the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Biophysics, Radiology, Nuclear Medicine and Imaging, Cell Biology, and Genetics.

Their research mainly centers on advanced fluorescence microscopy and optical imaging techniques, with key topics including:

  • Advanced Fluorescence Microscopy Techniques
  • Optical Imaging and Spectroscopy Techniques
  • Epigenetics and DNA Methylation
  • Single-cell and spatial transcriptomics
  • Zebrafish Biomedical Research Applications
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics

Rudolf Rigler's recent papers highlight applications of fluorescence correlation spectroscopy and fluorescence lifetime imaging microscopy in live cell analysis. Notable publications include:

  • "A strategy for designing allosteric modulators of transcription factor dimerization," 2020, Proceedings of the National Academy of Sciences
  • "Dynamic Cellular Cartography: Mapping the Local Determinants of Oligodendrocyte Transcription Factor 2 (OLIG2) Function in Live Cells Using Massively Parallel Fluorescence Correlation Spectroscopy Integrated with Fluorescence Lifetime Imaging Microscopy (mpFCS/FLIM)," 2021, Analytical Chemistry
  • "Mapping the Direction of Nucleocytoplasmic Transport of Glucocorticoid Receptor (GR) in Live Cells Using Two-Foci Cross-Correlation in Massively Parallel Fluorescence Correlation Spectroscopy (mpFCS)," 2023, Analytical Chemistry
  • "Mapping the Spatiotemporal Heterogeneity of Biomolecules Concentration, Mobility and Local Environment in Live Cells using Quantitative Time-Resolved Confocal Fluorescence Microscopy Imaging Without Scanning and Fluorescence Lifetime Imaging Microscopy," 2020, Biophysical Journal
  • "Scanning-Free functional Fluorescence Microscopy Imaging Toward Spatial Mapping of Biomolecular Information in Live Cell," 2022, The FASEB Journal

Frequent co-authors in their research include Sho Oasa, Vladana Vukojević, Lars Terenius, Aleksandar J. Krmpot, and Stanko N. Nikolić.

Rudolf Rigler's work has been published primarily in venues such as:

  • Analytical Chemistry
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • The FASEB Journal

The scientist has received recognition through various memberships and awards, including:

  • Member of Academia Europaea, 1998
  • German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften for Biochemistry and Biophysics, 1997
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Sorting single molecules: application to diagnostics and evolutionary biotechnology

    Manfred Eigen;Rudolf Rigler

  • Fluorescence correlation spectroscopy with high count rate and low background: analysis of translational diffusion

    R. Rigler;Ü. Mets;Ü. Mets;J. Widengren;P. Kask

  • Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution

    P. Schwille;F.J. Meyer-Almes;R. Rigler

  • Fluorescence correlation spectroscopy of triplet states in solution: a theoretical and experimental study

    Jerker Widengren;Uelo Mets;Rudolf Rigler

  • Photobleaching of Fluorescent Dyes under Conditions Used for Single-Molecule Detection: Evidence of Two-Step Photolysis.

    C. Eggeling;J. Widengren;R. Rigler;C. A. M. Seidel

  • Fluorescence correlation spectroscopy : theory and applications

    Rudolf Rigler;Elliot Elson

  • Rotational brownian motion and fluorescence intensify fluctuations

    M. Ehrenberg;R. Rigler

  • Resolution of Fluorescence Correlation Measurements

    Ulrich Meseth;Thorsten Wohland;Rudolf Rigler;Horst Vogel

  • Specific binding of proinsulin C-peptide to human cell membranes

    R. Rigler;A. Pramanik;P. Jonasson;G. Kratz

  • Conformational transitions monitored for single molecules in solution

    Lars Edman;Ulo Mets;Rudolf Rigler

  • The Standard Deviation in Fluorescence Correlation Spectroscopy

    Thorsten Wohland;Rudolf Rigler;Horst Vogel

  • Fluorescence correlations, single molecule detection and large number screening Applications in biotechnology

    Rudolf Rigler

  • Structure and dynamics of a fluorescent DNA oligomer containing the EcoRI recognition sequence: fluorescence, molecular dynamics, and NMR studies.

    Nordlund Tm;Andersson S;Nilsson L;Rigler R

  • Ultrasensitive hybridization analysis using fluorescence correlation spectroscopy

    Masataka Kinjo;Rudolf Rigler

  • Mechanisms of photobleaching investigated by fluorescence correlation spectroscopy

    Jerker Widengren;Rudolf Rigler

  • The fluctuating enzyme: a single molecule approach

    Lars Edman;Zeno Földes-Papp;Stefan Wennmalm;Rudolf Rigler

  • Triplet-state monitoring by fluorescence correlation spectroscopy.

    Jerker Widengren;Rudolf Rigler;Ülo Mets

  • Fluorescence correlation spectroscopy

    Rudolf Rigler;Elliot S. Elson

  • Polarized fluorescence and rotational brownian motion

    M. Ehrenberg;R. Rigler

  • Memory landscapes of single-enzyme molecules.

    Lars Edman;Rudolf Rigler

  • A temperature‐jump apparatus for fluorescence measurements

    Rudolf Rigler;Carl‐Roland Rabl;Thomas M. Jovin

  • FLUORESCENCE CORRELATION SPECTROSCOPY AS A TOOL TO INVESTIGATE CHEMICAL REACTIONS IN SOLUTIONS AND ON CELL SURFACES

    J Widengren;R Rigler

Frequent Co-Authors

Lennart Nilsson
Lennart Nilsson Karolinska Institute
Lars Terenius
Lars Terenius Karolinska Institute
Horst Vogel
Horst Vogel Shenzhen Institutes of Advanced Technology
Masataka Kinjo
Masataka Kinjo Hokkaido University
Alexander D. MacKerell
Alexander D. MacKerell University of Maryland, Baltimore
Astrid Gräslund
Astrid Gräslund Stockholm University
Ülo Langel
Ülo Langel Stockholm University
Måns Ehrenberg
Måns Ehrenberg Uppsala University
Arne Elofsson
Arne Elofsson Science for Life Laboratory
Hans Jörnvall
Hans Jörnvall Karolinska Institute

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