World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
68
Citations
16720
World Ranking
6519
National Ranking
475

Overview

Claus A.M. Seidel is affiliated with Heinrich Heine University Düsseldorf in Germany. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a total of 106 publications in these areas. Subfields within their work notably include molecular biology, biophysics, materials chemistry, structural biology, and cell biology.

Their scientific contributions cover several main topics, including:

  • Advanced Fluorescence Microscopy Techniques
  • Protein Structure and Dynamics
  • RNA Research and Splicing
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • RNA and protein synthesis mechanisms
  • Advanced Electron Microscopy Techniques and Applications

Seidel has contributed frequently to several publication venues, among them:

  • Biophysical Journal
  • Zenodo (CERN European Organization for Nuclear Research)
  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Their recent notable papers include:

  • "FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices" (2021) published in eLife
  • "Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions" (2022) published in Proceedings of the National Academy of Sciences
  • "Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins" (2023) published in Nature Methods
  • "PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends" (2024) published in Cell
  • "Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues" (2021) published in Chemical Society Reviews

Seidel collaborates regularly with several researchers, with frequent co-authors including:

  • Ralf Kühnemuth
  • Anders Barth
  • Suren Felekyan
  • Thomas-Otavio Peulen
  • Hugo Sanabria

Best Publications

  • NUCLEOBASE-SPECIFIC QUENCHING OF FLUORESCENT DYES. 1. NUCLEOBASE ONE-ELECTRON REDOX POTENTIALS AND THEIR CORRELATION WITH STATIC AND DYNAMIC QUENCHING EFFICIENCIES

    Claus A. M. Seidel;Andreas Schulz and;Markus H. M. Sauer

  • Photobleaching of Fluorescent Dyes under Conditions Used for Single-Molecule Detection: Evidence of Two-Step Photolysis.

    C. Eggeling;J. Widengren;R. Rigler;C. A. M. Seidel

  • Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

    Björn Hellenkamp;Björn Hellenkamp;Sonja Schmid;Sonja Schmid;Olga Doroshenko;Oleg Opanasyuk

  • A toolkit and benchmark study for FRET-restrained high-precision structural modeling

    Stanislav Kalinin;Thomas Peulen;Simon Sindbert;Paul J Rothwell

  • Proton-powered subunit rotation in single membrane-bound F0F1-ATP synthase.

    Manuel Diez;Boris Zimmermann;Michael Börsch;Marcelle König

  • Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy.

    C. Eggeling;J. R. Fries;L. Brand;R. Günther

  • Moderation of Arabidopsis Root Stemness by CLAVATA1 and ARABIDOPSIS CRINKLY4 Receptor Kinase Complexes

    Yvonne Stahl;Stephanie Grabowski;Andrea Bleckmann;Ralf Kühnemuth

  • Photochromicity and fluorescence lifetimes of green fluorescent protein

    George Striker;Vinod Subramaniam;Claus A. M. Seidel;Andreas Volkmer

  • Stem Cell Signaling in Arabidopsis Requires CRN to Localize CLV2 to the Plasma Membrane

    Andrea Bleckmann;Stefanie Weidtkamp-Peters;Claus A.M. Seidel;Ruݶdiger Simon

  • Accurate Single-Molecule FRET Studies Using Multiparameter Fluorescence Detection

    Evangelos Sisamakis;Alessandro Valeri;Stanislav Kalinin;Paul J Rothwell

  • Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1.

    M. Margittai;Jerker Widengren;E. Schweinberger;G. F. Schroder

  • Data registration and selective single-molecule analysis using multi-parameter fluorescence detection.

    C. Eggeling;S. Berger;L. Brand;J.R. Fries

  • Molecular photobleaching kinetics of Rhodamine 6G by one- and two-photon induced confocal fluorescence microscopy.

    Christian Eggeling;Andreas Volkmer;Claus A. M. Seidel

  • Accurate distance determination of nucleic acids via Förster resonance energy transfer: implications of dye linker length and rigidity.

    Simon Sindbert;Stanislav Kalinin;Hien Nguyen;Andrea Kienzler

  • Strategies to improve photostabilities in ultrasensitive fluorescence spectroscopy.

    Jerker Widengren;Andriy Chmyrov;Christian Eggeling;Per-Ake Löfdahl

  • An experimental comparison of the maximum likelihood estimation and nonlinear least-squares fluorescence lifetime analysis of single molecules.

    M Maus;M Cotlet;J Hofkens;T Gensch

  • FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

    Eitan Lerner;Anders Barth;Jelle Hendrix;Benjamin Ambrose

  • Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase:primer/template complexes

    Paul James Rothwell;Sylvia Berger;Oliver Kensch;Suren Felekyan

  • Separating structural heterogeneities from stochastic variations in fluorescence resonance energy transfer distributions via photon distribution analysis.

    Matthew Antonik;Suren Felekyan;and Alexander Gaiduk;Claus A. M. Seidel

  • Quantitative identification of different single molecules by selective time-resolved confocal fluorescence spectroscopy.

    J. R. Fries;L. Brand;C. Eggeling;M. Koellner

  • Single-molecule detection and identification of multiple species by multiparameter fluorescence detection.

    Jerker Widengren;Volodymyr Kudryavtsev;Matthew Antonik;Sylvia Berger

  • Identification of Single Molecules in Aqueous Solution by Time-Resolved Fluorescence Anisotropy

    J. Schaffer;A. Volkmer;C. Eggeling;V. Subramaniam

  • Single-molecule FRET measures bends and kinks in DNA

    Anna K. Woźniak;Gunnar F. Schröder;Helmut Grubmüller;Claus A. M. Seidel

Frequent Co-Authors

Holger Gohlke
Holger Gohlke Heinrich Heine University Düsseldorf
Christian Herrmann
Christian Herrmann Ruhr University Bochum
Don C. Lamb
Don C. Lamb Ludwig-Maximilians-Universität München
Benjamin Schuler
Benjamin Schuler University of Zurich
Peter Tompa
Peter Tompa Vrije Universiteit Brussel
Philip Tinnefeld
Philip Tinnefeld Ludwig-Maximilians-Universität München
Edward A. Lemke
Edward A. Lemke Johannes Gutenberg University of Mainz
Rüdiger Simon
Rüdiger Simon Heinrich Heine University Düsseldorf
Karl-Erich Jaeger
Karl-Erich Jaeger Heinrich Heine University Düsseldorf
Helmut Grubmüller
Helmut Grubmüller Max Planck Society

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a Chemistry degree in the USA opens doors to various career options, many of which offer online learning pathways. For those interested in legal aspects of chemistry, pursuing a paralegal degree can provide a foundation in compliance and regulatory work.

Chemistry graduates often consider roles in healthcare, such as pharmaceutical sales. Understanding how much do pharmaceutical sales reps make is crucial for those weighing this lucrative career against others in the science sector.

For a more clinical path, becoming a pharmacist is closely aligned with chemistry but requires dedication, as seen in discussions on is it hard to become a pharmacist. This career involves rigorous education and licensing, but offers strong job stability.

Alternatively, roles such as an autopsy technician blend chemistry knowledge with forensic science. Learning autopsy technician career requirements can help graduates decide if this behind-the-scenes profession fits their skills and interests.

Best Scientists Citing Claus A.M. Seidel

Trending Scientists