World's Best Scientists 2026 revealed!
Christian Herrmann

Christian Herrmann

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
13647
World Ranking
9245
National Ranking
676

Overview

Christian Herrmann is affiliated with Ruhr University Bochum in Germany. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with specific focus on Molecular Biology, Cell Biology, Immunology, Materials Chemistry, and Biophysics.

Their main research topics include:

  • Enzyme Structure and Function
  • Endoplasmic Reticulum Stress and Disease
  • Immune Response and Inflammation
  • Inflammasome and Immune Disorders
  • Interferon and Immune Responses
  • Protein Structure and Dynamics
  • Photosynthetic Processes and Mechanisms

Christian Herrmann has published research in various scientific venues, with multiple contributions to The EMBO Journal. Other frequent publication venues include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of Molecular Biology
  • FEBS Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent papers authored or co-authored by Herrmann feature investigations related to immune response mechanisms and protein interactions. Selected recent publications include:

  • "Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions" (2020) in The EMBO Journal
  • "LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro" (2023) in Proceedings of the National Academy of Sciences
  • "ATP-binding and hydrolysis of human NLRP3" (2022) in Communications Biology
  • "Conformational Preferences of an Intrinsically Disordered Protein Domain: A Case Study for Modern Force Fields" (2020) in The Journal of Physical Chemistry B
  • "Disordered Regions Flanking the Binding Interface Modulate Affinity between CBP and NCOA" (2022) in Journal of Molecular Biology

Collaboration is an important aspect of Herrmann's work, with several frequent co-authors including Miriam Kutsch, Linda Sistemich, Semra İnce, Julian Folz, and Claus A. M. Seidel. These partnerships indicate an active engagement in multidisciplinary research projects.

Best Publications

  • The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue.

    Nicolas Nassar;Gudrun Horn;Christian A. Herrmann;Anna Scherer

  • Quantitative Analysis of the Complex between p21ras and the Ras-binding Domain of the Human Raf-1 Protein Kinase (∗)

    Christian Herrmann;George A. Martin;Alfred Wittinghofer

  • Differential Interaction of the Ras Family GTP-binding Proteins H-Ras, Rap1A, and R-Ras with the Putative Effector Molecules Raf Kinase and Ral-Guanine Nucleotide Exchange Factor*

    Christian Herrmann;Gudrun Horn;Marcel Spaargaren;Alfred Wittinghofer

  • Dynamic properties of the Ras switch I region and its importance for binding to effectors.

    Michael Spoerner;Christian Herrmann;Ingrid R. Vetter;Hans Robert Kalbitzer

  • Protein denaturation by ionic liquids and the Hofmeister series: a case study of aqueous solutions of ribonuclease A.

    Diana Constantinescu;Hermann Weingärtner;Christian Herrmann

  • Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.

    Balaji Prakash;Gerrit J. K. Praefcke;Louis Renault;Alfred Wittinghofer

  • Protein Stabilization by Macromolecular Crowding through Enthalpy Rather Than Entropy

    Michael Senske;Lisa Törk;Benjamin Born;Martina Havenith

  • Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase.

    Michael Hothorn;Heinz Neumann;Esther D. Lenherr;Mark Wehner

  • How ionic liquids can help to stabilize native proteins.

    Hermann Weingärtner;Chiara Cabrele;Christian Herrmann

  • Ligand Discrimination by TPR Domains RELEVANCE AND SELECTIVITY OF EEVD-RECOGNITION IN Hsp70·Hop·Hsp90 COMPLEXES

    Achim Brinker;Clemens Scheufler;Florian von der Mülbe;Burkhard Fleckenstein

  • Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

    Matthias Geyer;Thomas Schweins;Christian Herrmann;Thomas Prisner

  • Patterns of protein unfolding and protein aggregation in ionic liquids.

    Diana Constatinescu;Christian Herrmann;Hermann Weingärtner

  • Ras/Rap effector specificity determined by charge reversal

    Nicolas Nassar;Gudrun Horn;Christian Herrmann;Christoph Block

  • Ras-effector interactions: after one decade.

    Christian Herrmann

  • How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP

    Agnidipta Ghosh;Gerrit J. K. Praefcke;Louis Renault;Alfred Wittinghofer

  • Recognizing and Defining True Ras Binding Domains I: Biochemical Analysis

    Sabine Wohlgemuth;Christina Kiel;Astrid Krämer;Luis Serrano

  • Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo

    Christoph Block;Ralf Janknecht;Christian Herrmann;Nicolas Nassar

  • The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria

    Thomas C. Marlovits;Winfried Haase;Christian Herrmann;Stephen G. Aller

  • Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily.

    Thomas Linnemann;Matthias Geyer;Birgit K. Jaitner;Christoph Block

  • Triphosphate structure of guanylate‐binding protein 1 and implications for nucleotide binding and GTPase mechanism

    Balaji Prakash;Louis Renault;Gerrit J.K. Praefcke;Christian Herrmann

Frequent Co-Authors

Alfred Wittinghofer
Alfred Wittinghofer Max Planck Society
Hans Robert Kalbitzer
Hans Robert Kalbitzer University of Regensburg
Claus A.M. Seidel
Claus A.M. Seidel Heinrich Heine University Düsseldorf
Matthias Geyer
Matthias Geyer University of Bonn
Ingrid R. Vetter
Ingrid R. Vetter Max Planck Society
Michael Stürzl
Michael Stürzl University of Erlangen-Nuremberg
Martin Engelhard
Martin Engelhard Max Planck Society
Martina Havenith
Martina Havenith Ruhr University Bochum
Burkhard König
Burkhard König University of Regensburg
Rolf Heumann
Rolf Heumann Ruhr University Bochum

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry opens the door to a diverse range of online degrees and careers in healthcare, research, and information management. For those interested in administrative paths, becoming a medical coder is a popular option. If you’re wondering how much does a medical coder make, salaries are competitive and offer room for advancement. However, it’s important to weigh whether is medical coding a good job for you, by considering both the pros (such as flexibility and demand) and the potential cons (like repetitive tasks).

Advancing your education can also lead to deeper roles in health data and patient information. Many universities now offer health information management degree online programs, allowing you to earn credentials without attending on-campus classes. For those more drawn to health sciences and human wellness, pursuing an online nutrition masters can prepare you for specialized jobs in nutrition counseling, research, or public health. With these online pathways, biology and biochemistry students have flexible, affordable ways to launch rewarding healthcare careers.

Best Scientists Citing Christian Herrmann

Trending Scientists

Recently Published Articles