Mohammad Reza Ahmadian

Overview

Best Publications

• The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

  Klaus Scheffzek;Mohammad Reza Ahmadian;Wolfgang Kabsch;Lisa Wiesmüller

  2205
  Citations

• CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

  Imke Tiede;Gerhard Fritz;Susanne Strand;Daniela Poppe

  1024
  Citations

• GTPase-activating proteins: helping hands to complement an active site

  Klaus Scheffzek;Mohammad Reza Ahmadian;Alfred Wittinghofer

  597
  Citations

• Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

  Mohammad Reza Ahmadian;Patricia Stege;Klaus Scheffzek;Alfred Wittinghofer

  487
  Citations

• A restricted spectrum of NRAS mutations causes Noonan syndrome

  Ion C. Cirstea;Kerstin Kutsche;Radovan Dvorsky;Lothar Gremer

  354
  Citations

• Structural and mechanistic insights into the interaction between Rho and mammalian Dia

  Rolf Rose;Michael Weyand;Michael Lammers;Toshimasa Ishizaki

  337
  Citations

• Formation of a transition-state analog of the Ras GTPase reaction by Ras-GDP, tetrafluoroaluminate, and GTPase-activating proteins.

  Rohit Mittal;Mohammad Reza Ahmadian;Roger S. Goody;Alfred Wittinghofer

  267
  Citations

• Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules.

  Francis P.G. van Horck;M. Reza Ahmadian;Lars C. Haeusler;Wouter H. Moolenaar

  239
  Citations

• Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.

  Klaus Scheffzek;Alfred Lautwein;Wolfgang Kabsch;Mohammad Reza Ahmadian

  228
  Citations

• Structural analysis of the GAP‐related domain from neurofibromin and its implications

  Klaus Scheffzek;Mohammad Reza Ahmadian;Lisa Wiesmüller;Wolfgang Kabsch

  210
  Citations

• Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase.

  Dennis Fiegen;Lars−Christian Haeusler;Lars Blumenstein;Ulrike Herbrand

  209
  Citations

• GTPase activating proteins: structural and functional insights 18 years after discovery

  Klaus Scheffzek;Mohammad Reza Ahmadian

  207
  Citations

• Selective Disactivation of Neurofibromin GAP Activity in Neurofibromatosis Type 1 (NF1)

  A. Klose;M. R. Ahmadian;M. Schuelke;K. Scheffzek

  206
  Citations

• Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network

  Aurélie Caye;Marion Strullu;Fabien Guidez;Bruno Cassinat

  201
  Citations

• Always look on the bright site of Rho: structural implications for a conserved intermolecular interface.

  Radovan Dvorsky;Mohammad Reza Ahmadian

  200
  Citations

• Rho-kinase: regulation, (dys)function, and inhibition.

  Ehsan Amin;Badri Nath Dubey;Si-Cai Zhang;Lothar Gremer

  200
  Citations

• Guanosine triphosphatase stimulation of oncogenic Ras mutants

  Mohammad Reza Ahmadian;Tsaffrir Zor;Dorothee Vogt;Wolfgang Kabsch

  196
  Citations

• Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders

  Lothar Gremer;Torsten Merbitz-Zahradnik;Radovan Dvorsky;Ion Cristian Cirstea

  195
  Citations

• Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy

  Mohammad Reza Ahmadian;Ulrike Hoffmann;Roger S. Goody;Alfred Wittinghofer

  189
  Citations

• The interaction of Ras with GTPase-activating proteins

  Alfred Wittinghofer;Klaus Scheffzek;Mohammad Reza Ahmadian

  180
  Citations