Tim Clausen

Overview

Best Publications

• The HtrA Family of Proteases: Implications for Protein Composition and Cell Fate

  Tim Clausen;Christopher Southan;Michael Ehrmann

  793
  Citations

• Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine

  Tobias Krojer;Marta Garrido-Franco;Robert Huber;Michael Ehrmann

  486
  Citations

• HTRA proteases: regulated proteolysis in protein quality control

  Tim Clausen;Markus Kaiser;Robert Huber;Michael Ehrmann;Michael Ehrmann

  485
  Citations

• Structural basis for the regulated protease and chaperone function of DegP

  Tobias Krojer;Justyna Sawa;Eva Schäfer;Helen R. Saibil

  431
  Citations

• Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.

  Corinna Wilken;Karina Kitzing;Robert Kurzbauer;Michael Ehrmann

  333
  Citations

• The role of human HtrA1 in arthritic disease.

  Sandra Grau;Peter J. Richards;Briedgeen Kerr;Clare Elizabeth Hughes

  327
  Citations

• Molecular Machines for Protein Degradation

  Michael Groll;Matthias Bochtler;Hans Brandstetter;Tim Clausen

  282
  Citations

• Proteolysis as a Regulatory Mechanism

  Michael Ehrmann;Tim Clausen

  272
  Citations

• Arginine phosphorylation marks proteins for degradation by a Clp protease

  Débora Broch Trentini;Marcin Józef Suskiewicz;Alexander Heuck;Robert Kurzbauer

  249
  Citations

• Implications of the serine protease HtrA1 in amyloid precursor protein processing

  Sandra Grau;Alfonso Baldi;Rossana Bussani;Xiaodan Tian

  245
  Citations

• Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.

  Tim Clausen;Robert Huber;Bernd Laber;Hans-Dieter Pohlenz

  232
  Citations

• Human CLP1 mutations alter tRNA biogenesis affecting both peripheral and central nervous system function

  Ender Karaca;Stefan Weitzer;Davut Pehlivan;Hiroshi Shiraishi

  219
  Citations

• The 1.3 Å Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes

  Karina Kitzing;Thérésa Bridget Fitzpatrick;Corinna Wilken;Justyna Sawa

  209
  Citations

• McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR

  Jakob Fuhrmann;Andreas Schmidt;Silvia Spiess;Anita Lehner

  201
  Citations

• Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.

  Jens T Kaiser;Tim Clausen;Gleb P Bourenkow;Hans-D Bartunik

  201
  Citations

• Mutations in the β-Tubulin Gene TUBB5 Cause Microcephaly with Structural Brain Abnormalities

  Martin Breuss;Julian Ik-Tsen Heng;Karine Poirier;Guoling Tian

  195
  Citations

• A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

  Madlen Stephani;Lorenzo Picchianti;Lorenzo Picchianti;Alexander Gajic;Rebecca Beveridge

  192
  Citations

• Protein Quality Control in the Bacterial Periplasm

  Melisa Merdanovic;Tim Clausen;Markus Kaiser;Robert Huber

  191
  Citations

• A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors

  Francesca Malvezzi;Gabriele Litos;Alexander Schleiffer;Alexander Heuck

  170
  Citations

• The HtrA Family of Proteases: Implications for Protein Composition and Cell Fate: Implications for Protein Composition and Cell Fate

  Michael Ehrmann;Tim Clausen;Chris Southan

  0
  Citations