World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9172
World Ranking
13452
National Ranking
960

Overview

Markus Kaiser is affiliated with the University of Duisburg-Essen in Germany. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Plant Science, Oncology, Biotechnology, and Cell Biology.

The scientist's research topics cover a range of subjects including:

  • Ubiquitin and proteasome pathways
  • Plant-Microbe Interactions and Immunity
  • Peptidase Inhibition and Analysis
  • Legume Nitrogen Fixing Symbiosis
  • Microbial Natural Products and Biosynthesis
  • Advanced Proteomics Techniques and Applications
  • 14-3-3 protein interactions

Markus Kaiser's frequent co-authors include:

  • Farnusch Kaschani (71 collaborations)
  • Renier A. L. van der Hoorn (23 collaborations)
  • David Podlesainski (14 collaborations)
  • Sabrina Ninck (10 collaborations)
  • Robert Huber (10 collaborations)

Publication venues where Markus Kaiser has frequently published are:

  • bioRxiv (Cold Spring Harbor Laboratory) - 29 publications
  • Nature Communications - 8 publications
  • Angewandte Chemie International Edition - 3 publications
  • Communications Biology - 3 publications
  • Journal of Biological Chemistry - 3 publications

Notable papers authored by or associated with Markus Kaiser include:

  • BacPROTACs mediate targeted protein degradation in bacteria, published in 2022 in Cell
  • Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method, published in 2020 in Biomolecules
  • Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions, published in 2020 in Nature Communications
  • Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival, published in 2023 in Cell
  • Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis, published in 2021 in Cell Reports

Best Publications

  • HTRA proteases: regulated proteolysis in protein quality control

    Tim Clausen;Markus Kaiser;Robert Huber;Michael Ehrmann;Michael Ehrmann

  • Fluorescence-based melting assays for studying quadruplex ligands

    Anne De Cian;Lionel Guittat;Markus Kaiser;Barbara Saccà

  • A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism

    Michael Groll;Barbara Schellenberg;André S. Bachmann;Crystal R. Archer

  • Small-molecule stabilization of protein-protein interactions: an underestimated concept in drug discovery?

    Philipp Thiel;Markus Kaiser;Christian Ottmann

  • LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B Encode Hydroxyalkyl α-Pyrone Synthases Required for Pollen Development and Sporopollenin Biosynthesis in Arabidopsis thaliana

    Sung Soo Kim;Etienne Grienenberger;Benjamin Lallemand;Che C. Colpitts

  • Biology-inspired synthesis of compound libraries

    Markus Kaiser;Stefan Wetzel;Kamal Kumar;Herbert Waldmann

  • Protein Quality Control in the Bacterial Periplasm

    Melisa Merdanovic;Tim Clausen;Markus Kaiser;Robert Huber

  • Substrate-induced remodeling of the active site regulates human HTRA1 activity.

    Linda Truebestein;Annette Tennstaedt;Timon Mönig;Tobias Krojer

  • Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition

    Jérôme Clerc;Michael Groll;Damir J. Illich;André S. Bachmann

  • Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.

    Manuela Molzan;Benjamin Schumacher;Corinna Ottmann;Angela Baljuls

  • Discovery of a New Class of Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B by Biology‐Oriented Synthesis

    Andrea Nören-Müller;Wolfram Wilk;Krishna Saxena;Harald Schwalbe

  • Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides.

    Pierre Buscaill;Balakumaran Chandrasekar;Nattapong Sanguankiattichai;Jiorgos Kourelis

  • An apoplastic peptide activates salicylic acid signalling in maize.

    Sebastian Ziemann;Karina van der Linde;Karina van der Linde;Urs Lahrmann;Beyda Acar

  • VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.

    Johannes van den Boom;Markus Wolf;Lena Weimann;Nina Schulze

  • The core structure of TMC-95A is a promising lead for reversible proteasome inhibition.

    Markus Kaiser;Michael Groll;Christian Renner;Robert Huber

  • Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3

    Christian Ottmann;Rolf Rose;Franziska Huttenlocher;Anna Cedzich

  • Determinants of amyloid fibril degradation by the PDZ protease HTRA1

    Simon Poepsel;Andreas Sprengel;Barbara Sacca;Farnusch Kaschani

  • N-Acylation during Glidobactin Biosynthesis by the Tridomain Nonribosomal Peptide Synthetase Module GlbF

    Heidi J. Imker;Daniel Krahn;Jérôme Clerc;Markus Kaiser

  • TMC-95-based inhibitor design provides evidence for the catalytic versatility of the proteasome

    Michael Groll;Marion Götz;Markus Kaiser;Elisabeth Weyher

  • Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 Expression.

    Diana Klein;Jennifer Steens;Alina Wiesemann;Florian Schulz

Frequent Co-Authors

Michael Ehrmann
Michael Ehrmann University of Duisburg-Essen
Renier A. L. van der Hoorn
Renier A. L. van der Hoorn University of Oxford
Michael Groll
Michael Groll Technical University of Munich
Robert Huber
Robert Huber University of Duisburg-Essen
Luis Moroder
Luis Moroder Max Planck Society
Herbert Waldmann
Herbert Waldmann Max Planck Society
Tim Clausen
Tim Clausen Research Institute of Molecular Pathology
Robert Dudler
Robert Dudler University of Zurich
Erich Kombrink
Erich Kombrink Max Planck Society
Herman S. Overkleeft
Herman S. Overkleeft Leiden University

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