Alexander Schleiffer focuses on Genetics, Cohesin, Establishment of sister chromatid cohesion, Homologous chromosome and Cohesin complex. Genetics is often connected to Protein structure in his work. His work deals with themes such as Meiosis II and Meiosis, which intersect with Homologous chromosome.
His Cohesin complex research incorporates elements of Separase, Anaphase and Cohesin loading. Anaphase and Cell biology are commonly linked in his work. His Cell biology study integrates concerns from other disciplines, such as SMC protein and Condensin complex.
Alexander Schleiffer mostly deals with Cell biology, Genetics, Homologous chromosome, Cohesin and Establishment of sister chromatid cohesion. Alexander Schleiffer interconnects Ubiquitin, Recombination, Mutant, Zebrafish and Regulator in the investigation of issues within Cell biology. His study in Genetics focuses on Anaphase, Transcription factor, Gene, Chromatin and Interkinesis.
His research investigates the connection with Anaphase and areas like Mitosis which intersect with concerns in Saccharomyces cerevisiae. His Homologous chromosome research is multidisciplinary, incorporating elements of Meiosis II, Meiosis and Genetic recombination. In his research on the topic of Separase, Prophase is strongly related with Cohesin loading.
Alexander Schleiffer spends much of his time researching Cell biology, Ubiquitin ligase, Ubiquitin, Recombination and Mutant. Many of his research projects under Cell biology are closely connected to Membrane protein with Membrane protein, tying the diverse disciplines of science together. His work in the fields of Ubiquitin ligase, such as Protein ubiquitination, overlaps with other areas such as Dynein and Cerebrovascular disorder.
His research in Recombination intersects with topics in Homologous recombination, Meiosis and Homologous chromosome. His Meiosis research focuses on DNA and how it relates to Cyclin-dependent kinase 2 and Chromosomal crossover. The Mutant study combines topics in areas such as Regulator and Apoptosis.
Alexander Schleiffer mainly focuses on Cell biology, PRDM9, Transcription Activation, Reading frame and Trans activation. His research on Cell biology focuses in particular on Endoplasmic-reticulum-associated protein degradation. PRDM9 combines with fields such as Meiosis, Homologous chromosome, Recombination, Homologous recombination and Pseudoautosomal region in his investigation.
With his scientific publications, his incorporates both Meiosis and Autosome. His work carried out in the field of Transcription Activation brings together such families of science as Regulation of gene expression, Transcription factor, Transcription and Computational biology.
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Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.
Attila Tóth;Rafal Ciosk;Frank Uhlmann;Marta Galova.
Genes & Development (1999)
Wapl Controls the Dynamic Association of Cohesin with Chromatin
Stephanie Kueng;Björn Hegemann;Beate H. Peters;Jesse J. Lipp.
Cell (2006)
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
James R. A. Hutchins;Yusuke Toyoda;Björn Hegemann;Ina Poser.
Science (2010)
Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl
Tomoko Nishiyama;Rene Ladurner;Julia Schmitz;Emanuel Kreidl.
Cell (2010)
A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction
Pawel Pasierbek;Michael Jantsch;Martin Melcher;Alexander Schleiffer.
Genes & Development (2001)
Functional Genomics Identifies Monopolin: A Kinetochore Protein Required for Segregation of Homologs during Meiosis I
Attila Tóth;Kirsten P. Rabitsch;Marta Gálová;Alexander Schleiffer.
Cell (2000)
A screen for genes required for meiosis and spore formation based on whole-genome expression
Kirsten P. Rabitsch;Attila Tóth;Marta Gálová;Alexander Schleiffer.
Current Biology (2001)
Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion.
Dmitri Ivanov;Alexander Schleiffer;Frank Eisenhaber;Karl Mechtler.
Current Biology (2002)
Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.
Alexander Schleiffer;Susanne Kaitna;Sebastian Maurer-Stroh;Michael Glotzer.
Molecular Cell (2003)
Human Scc4 Is Required for Cohesin Binding to Chromatin, Sister-Chromatid Cohesion, and Mitotic Progression
Erwan Watrin;Alexander Schleiffer;Koichi Tanaka;Frank Eisenhaber.
Current Biology (2006)
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