Bernard D. Santarsiero focuses on Stereochemistry, Biochemistry, Quinone, Absolute configuration and Protease. He is interested in Bicyclic molecule, which is a branch of Stereochemistry. His research in Quinone intersects with topics in Quinone Reductases, Menadione, Physalis and Isothermal titration calorimetry.
His Absolute configuration research is multidisciplinary, relying on both Glycoside and Carbon-13 NMR. In his research on the topic of Protease, Viral replication, Virology and Proteases is strongly related with Papain. In his study, Crystallography and Double bond is inextricably linked to Molecular geometry, which falls within the broad field of Carbene.
His scientific interests lie mostly in Stereochemistry, Crystal structure, Crystallography, Biochemistry and Medicinal chemistry. Bernard D. Santarsiero focuses mostly in the field of Stereochemistry, narrowing it down to matters related to Pharmacognosy and, in some cases, Terpenoid. Bernard D. Santarsiero has included themes like Inorganic compound, X-ray, X-ray crystallography, Molecule and Nuclear magnetic resonance spectroscopy in his Crystal structure study.
Bernard D. Santarsiero combines subjects such as Inorganic chemistry, Crystallization and Steric effects with his study of Crystallography. Biochemistry is represented through his Enzyme, Reductase and Hydrolase research. He regularly links together related areas like Carbon monoxide in his Medicinal chemistry studies.
His main research concerns Stereochemistry, Biochemistry, Crystal structure, Absolute configuration and Reductase. His study of Circular dichroism is a part of Stereochemistry. While the research belongs to areas of Biochemistry, he spends his time largely on the problem of Antibacterial activity, intersecting his research to questions surrounding Oxygenase, Structure–activity relationship and Tularemia.
His Crystal structure research is classified as research in Crystallography. The various areas that Bernard D. Santarsiero examines in his Absolute configuration study include Cancer, Human breast and Molecular conformation. His work carried out in the field of Reductase brings together such families of science as Porphyromonas gingivalis, Fatty acid synthesis and Antimicrobial, Microbiology.
Bernard D. Santarsiero mainly focuses on Stereochemistry, Biochemistry, Reductase, Cytotoxic T cell and Human melanoma. His work on Stereochemistry is being expanded to include thematically relevant topics such as Cell culture. His Racemic mixture research extends to Biochemistry, which is thematically connected.
His Reductase study combines topics from a wide range of disciplines, such as Glutathione peroxidase, Microbiology and Benzimidazole. His work in Cytotoxic T cell addresses subjects such as Molecular conformation, which are connected to disciplines such as Absolute configuration. His research in Human melanoma intersects with topics in Moiety and Cytotoxicity.
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Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.
Jill D. Dombrauckas;Bernard D. Santarsiero;Andrew D. Mesecar.
Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme
Kiira Ratia;Kumar Singh Saikatendu;Bernard D. Santarsiero;Naina Barretto.
Proceedings of the National Academy of Sciences of the United States of America (2006)
An approach to rapid protein crystallization using nanodroplets
B. D. Santarsiero;D. T. Yegian;C. C. Lee;G. Spraggon.
Journal of Applied Crystallography (2002)
Structural basis of autoregulation of phenylalanine hydroxylase
Bostjan Kobe;Ian G. Jennings;Colin M. House;Colin M. House;Belinda J. Michell.
Nature Structural & Molecular Biology (1999)
Methods and apparatus for performing array microcrystallizations
Сантарсьеро Бернард Д. (Us);Шультц Петер Г. (Us);Йеджиан Дерек Т. (Us);Нордмейер Роберт А. (Us).
New Chemical Constituents of Euphorbia quinquecostata and Absolute Configuration Assignment by a Convenient Mosher Ester Procedure Carried Out in NMR Tubes
Bao Ning Su;Eun Jung Park;Zakaria H. Mbwambo;Bernard D. Santarsiero.
Journal of Natural Products (2002)
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris.
Bang Yeon Hwang;Bao Ning Su;Heebyung Chai;Qiuwen Mi.
Journal of Organic Chemistry (2004)
Pleiotropic mechanisms facilitated by resveratrol and its metabolites
Barbara Calamini;Kiira Ratia;Michael G. Malkowski;Muriel Cuendet.
Biochemical Journal (2010)
Enantioselective synthesis of α-amino acid derivatives via the stereoselective alkylation of a homochiral glycine enolate synthon
Joseph F. Dellaria;Bernard D. Santarsiero.
Journal of Organic Chemistry (1989)
Kinetics and mechanism of the insertion of olefins into niobium- and tantalum-hydride bonds: a study of the competition between steric and electronic effects
Barbara J. Burger;Bernard D. Santarsiero;Mark S. Trimmer;John E. Bercaw.
Journal of the American Chemical Society (1988)
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