World's Best Scientists 2026 revealed!

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Microbiology

D-Index
92
Citations
24692
World Ranking
633
National Ranking
294

Genetics

D-Index
91
Citations
24319
World Ranking
1053
National Ranking
511

Research.com Recognitions

  • 1990 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David Dubnau is affiliated with Rutgers, The State University of New Jersey in the United States. Their work primarily lies within the broad field of Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Molecular Biology, Genetics, Ecology, Molecular Medicine, and Materials Chemistry.

Their research covers a range of topics, notably:

  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing
  • Enzyme Structure and Function
  • Bacillus and Francisella bacterial research

Frequent publication venues for David Dubnau include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • Biophysical Journal
  • Nature Communications
  • Proceedings of the National Academy of Sciences

The scientist has a track record of collaboration with several co-authors who have contributed to their work multiple times. These include Jeanette Hahn, Ishtiyaq Ahmed, Matthew B. Neiditch, Micaela DeSantis, and Eugenie Dubnau.

Selected recent papers demonstrate their involvement in molecular and bacterial genetics research:

  • "Structure-function studies reveal ComEA contains an oligomerization domain essential for transformation in gram-positive bacteria," 2022, Nature Communications
  • "Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis," 2021, mBio
  • "Formation of a stable RNase Y-RicT (YaaT) complex requires RicA (YmcA) and RicF (YlbF)," 2023, mBio
  • "ComFB, a new widespread family of c-di-NMP receptor proteins," 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • "Formation of a stable RNase Y-RicT (YaaT) complex requires RicA (YmcA) and RicF (YlbF)," 2023, bioRxiv (Cold Spring Harbor Laboratory)

David Dubnau was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 1990.

Best Publications

  • Bistability in bacteria

    David Dubnau;Richard Losick;Richard Losick

  • DNA uptake during bacterial transformation

    Unknown

  • Noise in gene expression determines cell fate in Bacillus subtilis.

    Hédia Maamar;Arjun Raj;David Dubnau

  • Characterization of Staphylococcus aureus plasmids introduced by transformation into Bacillus subtilis.

    T J Gryczan;S Contente;D Dubnau

  • DNA uptake in bacteria.

    Unknown

  • Fate of transforming DNA following uptake by competent Bacillus subtilis. I. Formation and properties of the donor-recipient complex.

    David Dubnau;Rosa Davidoff-Abelson

  • The Ins and Outs of DNA Transfer in Bacteria

    Inês Chen;Peter J. Christie;David Dubnau

  • Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor

    Kürşad Turgay;Jeanette Hahn;Jan Burghoorn;David Dubnau

  • Bistability in the Bacillus subtilis K‐state (competence) system requires a positive feedback loop

    Hédia Maamar;David Dubnau

  • Genetic competence in Bacillus subtilis.

    Unknown

  • Fate of transforming DNA following uptake by competent Bacillus subtilis

    David Dubnau;Carol Cirigliano

  • Microarray analysis of the Bacillus subtilis K-state: genome-wide expression changes dependent on ComK.

    Randy M. Berka;Jeanette Hahn;Mark Albano;Irena Draskovic

  • Expression of competence genes in Bacillus subtilis.

    M. Albano;J. Hahn;David Dubnau

  • Genetic mapping in Bacillus subtilis.

    David Dubnau;Claire Goldthwaite;Issar Smith;Julius Marmur

  • Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis.

    Kürşad Turgay;Leendert W. Hamoen;Gerard Venema;David Dubnau

  • comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis

    Douwe van Sinderen;Amy Luttinger;Liyun Kong;David Dubnau

  • Gene conservation in Bacillus species. I. Conserved genetic and nucleic acid base sequence homologies

    David Dubnau;Issar Smith;Pierre Morell;Julius Marmur

  • A Bacillus subtilis regulatory gene product for genetic competence and sporulation resembles sensor protein members of the bacterial two-component signal-transduction systems.

    Y Weinrauch;R Penchev;E Dubnau;I Smith

  • Conformational alteration of mRNA structure and the posttranscriptional regulation of erythromycin-induced drug resistance.

    T.J. Gryczan;G. Grandi;J. Hahn;R. Grandi

  • Translational attenuation: the regulation of bacterial resistance to the macrolide-lincosamide-streptogramin B antibiotics.

    David Dubnau;Masayasu Nomura

  • Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.

    M Albano;R Breitling;D A Dubnau

  • ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA.

    M. Roggiani;David Dubnau

  • Specific activation of the Bacillus quorum-sensing systems by isoprenylated pheromone variants

    Mireille Ansaldi;Darja Marolt;Darja Marolt;Tina Stebe;Tina Stebe;Ines Mandic-Mulec

  • Genetic competence in Bacillus subtilis

    Unknown

Frequent Co-Authors

Issar Smith
Issar Smith Rutgers, The State University of New Jersey
Leendert W. Hamoen
Leendert W. Hamoen University of Amsterdam
Youji Sakagami
Youji Sakagami Nagoya University
Ileana M. Cristea
Ileana M. Cristea Princeton University
Guido Grandi
Guido Grandi University of Trento
Julius Marmur
Julius Marmur Albert Einstein College of Medicine
Nancy Guillén
Nancy Guillén Institut Pasteur
Abraham Pinter
Abraham Pinter Rutgers, The State University of New Jersey
Oscar P. Kuipers
Oscar P. Kuipers University of Groningen
Richard Losick
Richard Losick Harvard University

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