World's Best Scientists 2026 revealed!
Tarek Msadek

Tarek Msadek

D-Index & Metrics

Microbiology

D-Index
56
Citations
10664
World Ranking
3710
National Ranking
215

Genetics

D-Index
56
Citations
10498
World Ranking
3514
National Ranking
178

Overview

Tarek Msadek is affiliated with the Institut Pasteur in France and focuses their research primarily in the fields of Biochemistry, Genetics, Molecular Biology, and Medicine. Their work addresses key areas within Infectious Diseases, Molecular Biology, Genetics, and Ecology.

The scientist's research topics cover diverse issues related to microbial resistance and bacterial behavior. These include:

  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Bacterial Genetics and Biotechnology
  • Antifungal resistance and susceptibility
  • Bacteriophages and microbial interactions

Tarek Msadek has contributed to several publications with a focus on Staphylococcus aureus and its resistance mechanisms. Notable recent papers include:

  • Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms, 2022, Nature Communications
  • Timely excision of prophage Φ13 is essential for the Staphylococcus aureus infectious process, 2025, Infection and Immunity
  • MRSA emerges through natural transformation, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Programmed in vivo excision of prophage Φ13 is an essential timing device for the Staphylococcus aureus infectious process, 2025, bioRxiv (Cold Spring Harbor Laboratory)
  • In memoriam Julian Edmund Davies (1932-2025), 2025, Research in Microbiology

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Infection and Immunity, and Research in Microbiology.

Collaborations feature prominently in their work, with coauthors including Mais Maree, Le Thuy Thi Nguyen, Ryosuke L. Ohniwa, Masato Higashide, and Kazuya Morikawa, all of whom have coauthored multiple papers alongside them.

Best Publications

  • Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease.

    Philippe Glaser;Christophe Rusniok;Carmen Buchrieser;Fabien Chevalier

  • CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria

    Isabelle Derré;Georges Rapoport;Tarek Msadek

  • New Insights into the WalK/WalR (YycG/YycF) Essential Signal Transduction Pathway Reveal a Major Role in Controlling Cell Wall Metabolism and Biofilm Formation in Staphylococcus aureus

    Sarah Dubrac;Ivo Gomperts Boneca;Olivier Poupel;Tarek Msadek

  • A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway

    Sarah Dubrac;Paola Bisicchia;Kevin M. Devine;Tarek Msadek

  • Signal transduction pathway controlling synthesis of a class of degradative enzymes in Bacillus subtilis: expression of the regulatory genes and analysis of mutations in degS and degU

    T Msadek;F Kunst;D Henner;A Klier

  • Clp ATPases are required for stress tolerance, intracellular replication and biofilm formation in Staphylococcus aureus.

    Dorte Frees;Arnaud Chastanet;Saara Qazi;Karen Sørensen

  • Identification of Genes Controlled by the Essential YycG/YycF Two-Component System of Staphylococcus aureus

    Sarah Dubrac;Tarek Msadek

  • ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation.

    Tarek Msadek;Véronique Dartois;Frank Kunst;Marie‐Laure Herbaud

  • Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance

    Ulf Gerth;Elke Krüger;Isabelle Derré;Tarek Msadek

  • CovS/CovR of group B streptococcus: a two-component global regulatory system involved in virulence

    Marie-Cécile Lamy;Mohammed Zouine;Juliette Fert;Massimo Vergassola

  • Bacitracin and nisin resistance in Staphylococcus aureus: a novel pathway involving the BraS/BraR two-component system (SA2417/SA2418) and both the BraD/BraE and VraD/VraE ABC transporters

    Aurélia Hiron;Mélanie Falord;Mélanie Falord;Jaione Valle;Michel Débarbouillé;Michel Débarbouillé

  • Regulation of Streptococcus pneumoniae clp genes and their role in competence development and stress survival

    Arnaud Chastanet;Marc Prudhomme;Jean-Pierre Claverys;Tarek Msadek

  • The phosphorylation state of the DegU response regulator acts as a molecular switch allowing either degradative enzyme synthesis or expression of genetic competence in Bacillus subtilis.

    M K Dahl;T Msadek;F Kunst;G Rapoport

  • DegS-DegU and ComP-ComA modulator-effector pairs control expression of the Bacillus subtilis pleiotropic regulatory gene degQ.

    T Msadek;F Kunst;A Klier;G Rapoport

  • Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions

    Ulrike Mäder;Pierre Nicolas;Maren Depke;Jan Pané-Farré

  • MecB of Bacillus subtilis, a member of the ClpC ATPase family, is a pleiotropic regulator controlling competence gene expression and growth at high temperature.

    Tarek Msadek;Frank Kunst;Georges Rapoport

  • Genes controlled by the essential YycG/YycF two-component system of Bacillus subtilis revealed through a novel hybrid regulator approach.

    Alistair Howell;Sarah Dubrac;Kasper Krogh Andersen;David Noone

  • Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways.

    Mélanie Falord;Mélanie Falord;Ulrike Mäder;Aurélia Hiron;Aurélia Hiron;Michel Débarbouillé;Michel Débarbouillé

  • When the going gets tough: survival strategies and environmental signaling networks in Bacillus subtilis.

    Tarek Msadek

  • GraXSR Proteins Interact with the VraFG ABC Transporter To Form a Five-Component System Required for Cationic Antimicrobial Peptide Sensing and Resistance in Staphylococcus aureus

    Mélanie Falord;Gouzel Karimova;Gouzel Karimova;Aurélia Hiron;Aurélia Hiron;Tarek Msadek;Tarek Msadek

  • Differential activation of virulence gene expression by PrfA, the Listeria monocytogenes virulence regulator.

    B Sheehan;A Klarsfeld;T Msadek;P Cossart

Frequent Co-Authors

Georges Rapoport
Georges Rapoport Centre national de la recherche scientifique, CNRS
Frank Kunst
Frank Kunst Institut Pasteur
Michael Hecker
Michael Hecker University of Greifswald
Ulrike Mäder
Ulrike Mäder University of Greifswald
Olivier Dussurget
Olivier Dussurget Université Paris Cité
Claire Poyart
Claire Poyart Institut Cochin
Marie-Anne Nahori
Marie-Anne Nahori Institut Pasteur
Patrick Trieu-Cuot
Patrick Trieu-Cuot Institut Pasteur
Philippe Glaser
Philippe Glaser Institut Pasteur
Carmen Buchrieser
Carmen Buchrieser Institut Pasteur

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